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Ginsenoside Re

Product Name
Ginsenoside Re
CAS No.
52286-59-6
Chemical Name
Ginsenoside Re
Synonyms
DCR-020;Panaxoside;NSC 308877;ginsenosideb2;GINSENOSIDE RE;Sanchinoside Re;98%byHPLC/CH90650;Re Ginsenoside Re;Ginsenoside Re-RM;Ginsenoside Re (P)
CBNumber
CB5210824
Molecular Formula
C48H82O18
Formula Weight
947.17
MOL File
52286-59-6.mol
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Ginsenoside Re Property

Melting point:
201～203℃
Boiling point:
1011.8±65.0 °C(Predicted)
Density 
1.38±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
pka
12.85±0.70(Predicted)
form 
Solid
color 
White to Off-White
InChIKey
PWAOOJDMFUQOKB-WCZZMFLVSA-N
LogP
4.750 (est)
CAS DataBase Reference
52286-59-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22
Safety Statements 
26-36
WGK Germany 
3
RTECS 
LY9536700
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL89212
Product name
Ginsenoside Re
Purity
phyproof? Reference Substance
Packaging
10mg
Price
$240
Updated
2024/03/01
Sigma-Aldrich
Product number
77960
Product name
Ginsenoside Re
Purity
analytical standard
Packaging
10mg
Price
$388
Updated
2024/03/01
Sigma-Aldrich
Product number
03000590
Product name
Ginsenoside Re
Purity
primary pharmaceutical reference standard
Packaging
10mg
Price
$270.8
Updated
2024/03/01
TCI Chemical
Product number
G0551
Product name
Ginsenoside Re
Packaging
50MG
Price
$169
Updated
2024/03/01
TCI Chemical
Product number
G0551
Product name
Ginsenoside Re
Packaging
250MG
Price
$522
Updated
2024/03/01
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Ginsenoside Re Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

Ginsenoside Re is an extract from ginger, responsible for some of the pharmacological functions. It displays cardiac contractility, anti-ischemic and anti-arrythmic activities.

Definition

ChEBI: Ginsenoside Re is a ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. It has a role as a plant metabolite, an antioxidant, a neuroprotective agent, an anti-inflammatory agent, an antineoplastic agent and a nephroprotective agent. It is a 12beta-hydroxy steroid, a 3beta-hydroxy steroid, a beta-D-glucoside, a ginsenoside, a tetracyclic triterpenoid, a disaccharide derivative and a 3beta-hydroxy-4,4-dimethylsteroid. It derives from a hydride of a dammarane.

in vivo

Ginsenoside Re reduces insulin resistance in 3T3-L1 adipocytes and high-fat diet (HFD) rats through inhibition of JNK and NF-κB activation[2]. Intraperitoneal injection of lipopolysaccharide (LPS) at a dose of 20 mg/kg is lethal to mice, and 70% to 80% of the mice die within 60 h. However, pretreatment of the mice with Rg1 or Ginsenoside Re increases their survival rates in a dose-dependent manner. With the doses of Rg1 or Ginsenoside Re increase from 2.5 to 5 mg/kg, the survival rate is elevated from 60% to 90% (Rg1) or from 30% to 40% (Ginsenoside Re). All the mice administered Rg1 at a minimal dose of 10 mg/kg are protected from death compared to 80% survival of mice treated with an equal dose of Ginsenoside Re. To protect all the mice, 20 mg/kg Ginsenoside Re is needed. To investigate the anti-inflammatory potential of Rg1 and Ginsenoside Re, 1 mg/kg Rg1 or Ginsenoside Re is injected into rats and then challenged the animals with LPS. The injection procedure itself causes a transient stress-induced increase in body temperature of ~1.2°C in each group. Thereafter, LPS-challenged rats without pretreatment develope a robust biphasic fever, with the first peak reaching ~1.5°C at 2 h and the second peak reaching 1.8°C at 4 h. In contrast, the temperature changes for the Rg1-, Ginsenoside Re-, and TAK-242-treated groups are only 0.9, 1.2, and 0.8°C at 2 h and 1.3, 1.4, and 1.0°C at 4 h, respectively. Pretreatment with Rg1, Ginsenoside Re, or TAK-242 significantly attenuates LPS-induced alterations in body temperature[3].

target

AMPK | TLR | p38MAPK | HO-1 | TNF-α | Potassium Channel | NO | Calcium Channel | ERK | Akt | mTOR | CD4 | Calcium Channel | c-Src | NOS

IC 50

Aβ1-40; Aβ1-42; NF-κB; JNK

Ginsenoside Re Preparation Products And Raw materials

Raw materials

Preparation Products

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Ginsenoside Re Suppliers

Americas 1 China 268 Europe 1 France 2 Germany 3 India 3 Japan 1 United Kingdom 8 United States 26 Global 313
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
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+86-27-84254680
Email
aileen@chemfaces.com
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China
ProdList
6905
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55
Nanjing Yuanzhi Biotechnology Co. Ltd.
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15805159960
Email
1211550495@qq.com
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China
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Nanjing Digger Medical Technology Co. Ltd.
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025-025-51191215 18013836722
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025-51191215
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2399235533@qq.com
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China
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4933
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Nanjing Spring & Autumn Biological Engineering Co., Ltd.
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025-84430028 13815430202
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sale02@cqherb.com
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China
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Chengdu Nakeli Biotechnology Co., Ltd.
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028-61983833 19138982515
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3265827856
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3265827856@qq.com
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China
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1542
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58
Nanjing bingcheng Biotechnology Co., Ltd.
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18805194892
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2727751293@qq.com
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China
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Chengdu Biopurify Phytochemicals Ltd.
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+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
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China
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2376
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J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
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94657
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future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
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sales@jonln.com
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China
ProdList
1995
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Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
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6005
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View Lastest Price from Ginsenoside Re manufacturers

Apeloa production Co.,Limited
Product
Ginsenoside Re 52286-59-6
Price
US $1.00/g
Min. Order
1g
Purity
98%
Supply Ability
1000
Release date
2024-06-20
Shanghai Standard Technology Co., Ltd.
Product
Ginsenoside Re 52286-59-6
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-10-14
Shanghai Standard Technology Co., Ltd.
Product
Ginsenoside Re 52286-59-6
Price
US $0.00/mg
Min. Order
5mg
Purity
Analytical Standard
Supply Ability
10 g
Release date
2019-10-14

52286-59-6, Ginsenoside ReRelated Search:

GinsenosideRo Ginsenoside Rb1 Ginsenoside Rg1 20(R)-Ginsenoside Rg3 Ginsenoside Rh2 Ginseng extract TRIBULOSIDE ginsenoside Rh3 Ginsenoside Rc GINSENOSIDE F2 Panaxadiol Panaxatriol Ginsenoside-Rg5 Ginsenoside Rf GINSENOSIDE RB2 20R-Ginsenoside Rh2 Ginsenoside Rk3 GINSENOSIDEF1

  • chikusetsusaponinivc
  • b-D-Glucopyranoside, (3b,6a,12b)-20-(b-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl2-O-(6-deoxy-a-L-mannopyranosyl)-
  • (3β,6α,12β)-20-(β-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
  • DCR-020
  • DCR-020;PANAXOSIDE RE;GINSENOSIDE B2;CHIKUSETSUSAPONIN IVC
  • Ginsenoside Re 52286-59-6
  • ginsenosideb2
  • GINSENOSIDE GINSENOSIDE-RE
  • GINSENOSIDE RE
  • 2-O-(6-deoxy-alpha-L-mannopyranosyl)-(3beta,6alpha,12beta)-20-(beta-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl-beta-D-glucopyranoside
  • Ginsenoside Re std.
  • 98%byHPLC/CH90650
  • Panaxoside
  • GINSENOSIDE RE WITH HPLC
  • GINSENOSIDE-RE (GINSENOSIDE B2)
  • NSC 308877
  • Sanchinoside Re
  • Panaxoside RE, Ginsenoside B2, Chikusetsusaponin IVc
  • glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl2-O-(6-deoxy-α-L-mannopyranosyl)-
  • β-D-Glucopyranoside,(3β,6α,12β)-20-(β-D-
  • [20-(β-D-Glucopyranosyloxy)-3β,12β-dihydroxy-5α-dammar-24-en-6α-yl]2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
  • [20-(β-D-Glucopyranosyloxy)-3β,12β-dihydroxydammar-24-en-6α-yl]2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
  • 20-(β-D-Glucopyranosyloxy)-3β,12β-dihydroxy-5α-dammar-24-en-6α-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
  • ginsenoside-Re standard
  • Ginsenoside Re ,97%
  • β-D-Glucopyranoside, (3β,6α,12β)-20-(β-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-
  • (2S,3R,4R,5R,6S)-2-(((1R,2S,3R,4R,6R)-6-(((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-17-((S)-1-hydroxy-5-methyl-1-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hex-4-en-1-yl)-4,4,8,10,14-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthren-6-yl)oxy)-2,3-dihydroxy-4-(hydroxymethyl)cyclohexyl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol
  • (2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-2-(((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-((S)-6-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hept-5-en-2-yl)hexadecahydro-1H-cycl
  • (3beta,6alpha,12beta)-20-(beta-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-6-Deoxy-alpha-L-mannopyranosyl-beta-D-glucopyranoside
  • (2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-methyloxane-3,4,5-triol
  • 4-?Dihydroxyphenyl)?ethanone
  • Ginsenoside Re (P)
  • (2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-2-(((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-Dihydroxy-4,4,8,10,14-pentamethyl-17-((S)-6-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hept-5-en-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-6-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol
  • Re Ginsenoside Re
  • Ginsenoside Re(AS)
  • Ginsenoside Re-RM
  • β-?D-?Glucopyranoside, (3β,?6α,?12β)?-?20-?(β-?D-?glucopyranosyloxy)?-?3,?12-?dihydroxydammar-?24-?en-?6-?yl 2-?O-?(6-?deoxy-?α-?L-?mannopyranosyl)?-
  • 52286-59-6
  • 197-70-5
  • C48H82O18
  • Inhibitors
  • Ginsenoside series
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • The group of Ginsenosides
  • Saponins