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Ginsenoside Rb1

Product Name
Ginsenoside Rb1
CAS No.
41753-43-9
Chemical Name
Ginsenoside Rb1
Synonyms
GYPENOSIDE;GINSENOSIDE GINSENOSIDE-RB1;(3beta,12beta)-20-[(6-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl2-o-beta-d-glucopyranosyl-beta-d-glucopyranoside;NSC 310103;Gypenoside I;arasaponine1;gynosaponinc;Gypenoside Ⅲ;gypenosideiii;panaxsaponine
CBNumber
CB7237661
Molecular Formula
C54H92O23
Formula Weight
1109.29
MOL File
41753-43-9.mol
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Ginsenoside Rb1 Property

Melting point:
197.5°C
Boiling point:
766.35°C (rough estimate)
Density 
1.0971 (rough estimate)
refractive index 
1.6500 (estimate)
storage temp. 
2-8°C
solubility 
methanol: soluble9.80 - 10.20 mg/mL, clear, colorless to faintly yellow
pka
12.85±0.70(Predicted)
color 
Off-White to Pale Beige
Stability:
Hygroscopic
InChI
InChI=1/C54H92O23/c1-23(2)10-9-14-54(8,77-48-44(69)40(65)37(62)29(74-48)22-70-46-42(67)38(63)34(59)26(19-55)71-46)24-11-16-53(7)33(24)25(58)18-31-51(5)15-13-32(50(3,4)30(51)12-17-52(31,53)6)75-49-45(41(66)36(61)28(21-57)73-49)76-47-43(68)39(64)35(60)27(20-56)72-47/h10,24-49,55-69H,9,11-22H2,1-8H3/t24-,25+,26+,27+,28+,29+,30-,31+,32-,33-,34+,35+,36+,37+,38-,39-,40-,41-,42+,43+,44+,45+,46+,47-,48-,49-,51-,52+,53+,54-/s3
InChIKey
GZYPWOGIYAIIPV-VOKNSFSUNA-N
SMILES
[C@]12([H])C[C@H]([C@]3([H])[C@]([H])(CC[C@@]3(C)[C@]1(C)CC[C@@]1([H])C(C)(C)[C@@H](O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O[C@H]3[C@H](O)[C@H]([C@H](O)[C@@H](CO)O3)O)CO)CC[C@]21C)[C@](C)(CC/C=C(\C)/C)O[C@H]1[C@H](O)[C@H]([C@H](O)[C@@H](CO[C@H]2[C@H](O)[C@H]([C@H](O)[C@@H](CO)O2)O)O1)O)O |&1:0,3,4,6,10,12,16,21,23,25,26,28,30,32,33,35,36,38,47,49,58,59,61,62,64,67,68,70,71,73,r|
LogP
2.900 (est)
CAS DataBase Reference
41753-43-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi,T,F
Risk Statements 
20/21/22-39/23/24/25-23/24/25-11
Safety Statements 
26-36-45-36/37-16-7
WGK Germany 
3
RTECS 
LZ5856000
HS Code 
29389090
Toxicity
oms-rat-ipr 50 mg/kg CPBTAL 24,2400,76
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G0777
Product name
Ginsenoside-Rb1 from Panax ginseng (Korean ginseng) root
Purity
triterpenoid saponin
Packaging
5mg
Price
$652
Updated
2024/03/01
Sigma-Aldrich
Product number
00170580
Product name
Ginsenoside Rb1
Purity
primary pharmaceutical reference standard
Packaging
10mg
Price
$766
Updated
2024/03/01
Cayman Chemical
Product number
15319
Product name
Ginsenoside Rb1
Purity
≥98%
Packaging
5mg
Price
$93
Updated
2024/03/01
Cayman Chemical
Product number
15319
Product name
Ginsenoside Rb1
Purity
≥98%
Packaging
10mg
Price
$176
Updated
2024/03/01
Sigma-Aldrich
Product number
Y0001347
Product name
Ginsenoside Rb1
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0001347
Price
$220
Updated
2024/03/01
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Ginsenoside Rb1 Chemical Properties,Usage,Production

Uses

A major bioactive component of panax ginseng that promotes neurotransmitter release by modulating phosphorylation of synapsins through a cAMP-dependent protein kinase pathway. It has been reported to display immunostimulatory and anticancer effects.

Uses

Reference standard in the analysis of herbal medicinal products.

Definition

ChEBI: Ginsenoside Rb1 is a ginsenoside found in Panax ginseng and Panax japonicus var. major that is ginsenoside Rd in which the beta-D-glucopyranoside group at position 20 is replaced by a beta-D-glucopyranosyl-beta-D-glucopyranoside group. It has a role as a neuroprotective agent, an anti-obesity agent, an anti-inflammatory drug, an apoptosis inhibitor, a radical scavenger and a plant metabolite. It is a ginsenoside, a glycoside and a tetracyclic triterpenoid. It is functionally related to a ginsenoside Rd.

General Description

Ginsenoside Rb1 (Gypenoside Ⅲ) is a protopanaxadiol that has diverse in vitro and in vivo effects, including neuroprotective, anti-inflammatory, and anti-obesity actions. Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65. Ginsenoside Rb1 reduces the expressions of TLR3, TLR4 and TRAF-6, and down-regulates the levels of TNF-α, IFN-β and iNOS.

Biochem/physiol Actions

Triterpene saponin found in ginseng.

Safety Profile

Poison by intravenous route. Moderately toxic by intraperitoneal route. Mutation data reported. Whenheated to decomposition it emits acrid smoke and irritating fumes.

target

p38MAPK | JNK | GLUT | Akt | IFN-γ | IL Receptor | GSK-3 | HO-1 | PKA | Estrogen receptor | Progestogen receptor

Ginsenoside Rb1 Preparation Products And Raw materials

Raw materials

Preparation Products

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Ginsenoside Rb1 Suppliers

Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
7059
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55
Nanjing Yuanzhi Biotechnology Co. Ltd.
Tel
15805159960
Email
1211550495@qq.com
Country
China
ProdList
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58
Nanjing Digger Medical Technology Co. Ltd.
Tel
025-025-51191215 18013836722
Fax
025-51191215
Email
2399235533@qq.com
Country
China
ProdList
4933
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Nanjing puyi biotechnology co., LTD
Tel
025-58886740; 13814510036
Email
927565933@qq.com
Country
China
ProdList
1930
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58
Weifang Huazhi Biological Technology Co., Ltd.
Tel
025-84430028 13815430202
Email
sale02@cqherb.com
Country
China
ProdList
47
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58
Nanjing Dasf Biotechnology Co., Ltd.
Tel
025-+86-02585846866 +86-18094231287
Fax
025-83144123
Email
eric@dasfbio.com
Country
China
ProdList
1987
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Shanghai Yanchun Biopharmaceutical Technology Co., Ltd
Tel
4001-009266 17349750668
Email
product@sci-e.com
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China
ProdList
2812
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J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6013
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61
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
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61
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View Lastest Price from Ginsenoside Rb1 manufacturers

Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
Product
Ginsenoside Rb1 41753-43-9
Price
US $0.00/kg
Min. Order
0.1kg
Purity
50%-98% HPLC
Supply Ability
100kg
Release date
2024-03-14
Henan Fengda Chemical Co., Ltd
Product
Ginsenoside Rb1 41753-43-9
Price
US $34.00-1.40/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-26
Shaanxi Haibo Biotechnology Co., Ltd
Product
Ginsenoside Rb1 41753-43-9
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000ton
Release date
2023-08-21

41753-43-9, Ginsenoside Rb1 Related Search:


  • GINSENOSIDE GINSENOSIDE-RB1
  • GINSENOSIDE RB1
  • GINSENOSIDE RBL
  • (3beta,12beta)-20-[(6-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl2-o-beta-d-glucopyranosyl-beta-d-glucopyranoside
  • 2-O-beta-glucopyranosyl-(3beta,12beta)-20-[(6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl-beta-D-glucopyranoside
  • Ginsenoside Rb1 std.
  • ginsenoside-rb1from panax quinquefolium (american ginseng)root
  • Ginsenoside Rb1 (CAS# 41753-43-9)
  • GinsenosideRB1,SanchinosideE1
  • GINSENOSIDE Rb1 hplc
  • Gensenoside Rb1
  • GINSENOSIDE RB1 WITH HPLC
  • glucopyranosyl-β-D-glucopyranosyl)oxy]-12-
  • hydroxydammar-24-en-3-yl2-O-β-D-glucopyra
  • Notoginsenoside Rb1
  • Panaxoside Rb1
  • β-D-Glucopyranoside, (3β,12β)-20-[(6-O-β-D-
  • Gypenoside I
  • hydroxydammar-24-en-3-yl O-6-deoxy-α-L-
  • mannopyranosyl-(1→6)-O-[β-D-
  • (20S)-3β-[2-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyloxy]-20-[6-O-(β-D-glucopyranosyl)-β-D-glucopyranosyloxy]dammara-24-ene-12β-ol
  • [20-[(6-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)oxy]-12β-hydroxydammar-24-en-3β-yl]2-O-β-D-glucopyranosyl-β-D-glucopyranoside
  • 3β-[2-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyloxy]-20-[6-O-(β-D-glucopyranosyl)-β-D-glucopyranosyloxy]dammara-24-ene-12β-ol
  • ginsenoside-Rb1 standard
  • Ginsenoside Rb1 41753-43-9
  • (3-beta,12-beta)-20-((6-o-beta-d-glucopyranosyl-beta-d-beta-d-glucopyranosid
  • arasaponine1
  • glucopyranosyl)oxy)-12-hydroxydammar-24-en-3-yl2-o-beta-d-glucopyranosyl-
  • gynosaponinc
  • gypenosideiii
  • panaxsaponine
  • pseudoginsenosided
  • SANCHINOSIDE E1
  • GYPENOSIDE
  • Ginsenoside Rb1 ,98%
  • (3β,12β)-20-[(6-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydaMMar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
  • Purity of Ginsenoside Rg1
  • NSC 310103
  • Sanchinoside Rb1
  • Ginsenoside Rb1, froM Panax ginseng
  • Ginsenoside Rb1 (saponin of panax ginseng)
  • Ginsenoside-Rb1 from Panax ginseng (Korean ginseng) root
  • 2-O-β-Glucopyranosyl-(3β,12β)-20-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl β-D-glucopyranoside
  • Ginsenoside Rb1, 98%, from Panax ginseng C. A. Mey.
  • (3beta,12beta)-20-[(6-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl2-O-beta-D-glucopyranosyl-beta-D-glucopyranosi
  • Ginsenoside Rb1 CRS
  • Ginsenoside Rb1 RS
  • Gypenoside Ⅲ
  • β-D-Glucopyranoside, (3β,12β)-20-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-
  • (2R,3R,4S,5S,6R)-2-[[(2R,3S,4S,5R,6S)-6-[(2S)-2-[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-3-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-12-hydroxy-4,4,8,10,14-pentamethyl-2,3,
  • (2R,3R,4S,5S,6R)-2-[[(2R,3S,4S,5R,6S)-6-[(2S)-2-[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-3-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-12-hydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-en-2-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
  • (2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-4,5-Dihydroxy-2-(((3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-((S)-6-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)hept-5-en-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • Rb1 Ginsenoside Rb1
  • 41753-43-9
  • 41753-53-9
  • C54H92O23
  • C60H102O27
  • chemical reagent