KURARINONE
- Product Name
- KURARINONE
- CAS No.
- 34981-26-5
- Chemical Name
- KURARINONE
- Synonyms
- Marini;Kurarinon;KURARINONE;Kurarinone >=98% (HPLC);2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-(5-methyl-2-prop-1-en-2-ylhex-4-enyl)-2,3-dihydrochromen-4-one;(S)-2-(2,4-Dihydroxyphenyl)-7-hydroxy-5-methoxy-8-((R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl)chroman-4-one;2-(2,4-Dihydroxyphenyl)-2,3-dihydro-7-hydroxy-5-methoxy-8-[5-methyl-2-(1-methylethenyl)-4-hexenyl]-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one,2-(2,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-5-methoxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-,(2S)-
- CBNumber
- CB5230365
- Molecular Formula
- C26H30O6
- Formula Weight
- 438.51
- MOL File
- 34981-26-5.mol
KURARINONE Property
- Melting point:
- 117-119℃
- Boiling point:
- 651.4±55.0 °C(Predicted)
- Density
- 1?+-.0.06 g/cm3(Predicted)
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 7.49±0.40(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- PXT0001896
- Product name
- KURARINONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.75
- Updated
- 2021/12/16
- Product number
- JR8-N1225
- Product name
- Kurarinone(NewProduct)
- Purity
- 98%(HPLC)
- Packaging
- 250mg
- Price
- $628
- Updated
- 2021/12/16
- Product number
- 34981265
- Product name
- (S)-2-(2,4-Dihydroxyphenyl)-7-hydroxy-5-methoxy-8-((R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl)chroman-4-one
- Packaging
- 25mg
- Price
- $631.62
- Updated
- 2021/12/16
- Product number
- 4295
- Product name
- Kurarinone
- Packaging
- 20mg
- Price
- $690
- Updated
- 2021/12/16
- Product number
- JR8-N1225
- Product name
- Kurarinone(NewProduct)
- Purity
- 98%(HPLC)
- Packaging
- 500mg
- Price
- $998
- Updated
- 2021/12/16
KURARINONE Chemical Properties,Usage,Production
Definition
ChEBI: (2S)-(-)-kurarinone is a trihydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 7, 2' and 4', a lavandulyl group at position 8 and a methoxy group at position 5. Isolated from the roots of Sophora flavescens, it exhibits cytotoxicity against human myeloid leukemia HL-60 cells. It has a role as a metabolite and an antineoplastic agent. It is a trihydroxyflavanone, a monomethoxyflavanone and a member of 4'-hydroxyflavanones. It is functionally related to a (2S)-flavanone.
Biological Activity
Kurarinone, a flavonoid isolated from Sophora flavescens, inhibits the pathogenesis of experimental autoimmune encephalomyelitis by inhibiting the differentiation of Th1 and Th17 cells.
Physiological effects
Kurarinon has an anti-endothelial cell proliferative activity, and it has a significant inhibitory effect on endothelial cell proliferation with a median inhibitory concentration (IC50) of 12ug/ml.
KURARINONE Preparation Products And Raw materials
Raw materials
Preparation Products
KURARINONE Suppliers
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View Lastest Price from KURARINONE manufacturers
- Product
- Kurarinone 34981-26-5
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-03-27