ChemicalBook > CAS DataBase List > KURARINONE

KURARINONE

Product Name
KURARINONE
CAS No.
34981-26-5
Chemical Name
KURARINONE
Synonyms
Marini;Kurarinon;KURARINONE;Kurarinone >=98% (HPLC);2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-(5-methyl-2-prop-1-en-2-ylhex-4-enyl)-2,3-dihydrochromen-4-one;(S)-2-(2,4-Dihydroxyphenyl)-7-hydroxy-5-methoxy-8-((R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl)chroman-4-one;2-(2,4-Dihydroxyphenyl)-2,3-dihydro-7-hydroxy-5-methoxy-8-[5-methyl-2-(1-methylethenyl)-4-hexenyl]-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one,2-(2,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-5-methoxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-,(2S)-
CBNumber
CB5230365
Molecular Formula
C26H30O6
Formula Weight
438.51
MOL File
34981-26-5.mol
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KURARINONE Property

Melting point:
117-119℃
Boiling point:
651.4±55.0 °C(Predicted)
Density 
1?+-.0.06 g/cm3(Predicted)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
7.49±0.40(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
PXT0001896
Product name
KURARINONE
Purity
95.00%
Packaging
5MG
Price
$503.75
Updated
2021/12/16
JR MediChem
Product number
JR8-N1225
Product name
Kurarinone(NewProduct)
Purity
98%(HPLC)
Packaging
250mg
Price
$628
Updated
2021/12/16
Alichem
Product number
34981265
Product name
(S)-2-(2,4-Dihydroxyphenyl)-7-hydroxy-5-methoxy-8-((R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl)chroman-4-one
Packaging
25mg
Price
$631.62
Updated
2021/12/16
AvaChem
Product number
4295
Product name
Kurarinone
Packaging
20mg
Price
$690
Updated
2021/12/16
JR MediChem
Product number
JR8-N1225
Product name
Kurarinone(NewProduct)
Purity
98%(HPLC)
Packaging
500mg
Price
$998
Updated
2021/12/16
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KURARINONE Chemical Properties,Usage,Production

Definition

ChEBI: (2S)-(-)-kurarinone is a trihydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 7, 2' and 4', a lavandulyl group at position 8 and a methoxy group at position 5. Isolated from the roots of Sophora flavescens, it exhibits cytotoxicity against human myeloid leukemia HL-60 cells. It has a role as a metabolite and an antineoplastic agent. It is a trihydroxyflavanone, a monomethoxyflavanone and a member of 4'-hydroxyflavanones. It is functionally related to a (2S)-flavanone.

Biological Activity

Kurarinone, a flavonoid isolated from Sophora flavescens, inhibits the pathogenesis of experimental autoimmune encephalomyelitis by inhibiting the differentiation of Th1 and Th17 cells.

Physiological effects

Kurarinon has an anti-endothelial cell proliferative activity, and it has a significant inhibitory effect on endothelial cell proliferation with a median inhibitory concentration (IC50) of 12ug/ml.

KURARINONE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from KURARINONE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
KURARINONE 34981-26-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-08-09
Shanghai Standard Technology Co., Ltd.
Product
Kurarinone 34981-26-5
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-03-27

34981-26-5, KURARINONERelated Search:

Sodium oxide Tanshinone I Potassium chloride Sorbitol Rituximab Luteolin TRIFOLIRHIZIN Ammothamnine Matrine Sophoridine 13,14-Didehydromatridin-15-one 2'-HYDROXYFLAVANONE 5-Methoxy-4-chromanone 2,3-Dihydro-7-hydroxy-5-methoxy-2-phenyl-4H-1-benzopyran-4-one KURARINONE 4-(2-ETHOXYPHENYL)-2-METHYL-1-BUTENE 1-(3-(BUT-3-ENYL)PHENYL)ETHANONE 5-Methoxyflavanone

  • KURARINONE
  • Kurarinon
  • Marini
  • 4H-1-Benzopyran-4-one,2-(2,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-5-methoxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-,(2S)-
  • 2-(2,4-Dihydroxyphenyl)-2,3-dihydro-7-hydroxy-5-methoxy-8-[5-methyl-2-(1-methylethenyl)-4-hexenyl]-4H-1-benzopyran-4-one
  • Kurarinone >=98% (HPLC)
  • 2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-(5-methyl-2-prop-1-en-2-ylhex-4-enyl)-2,3-dihydrochromen-4-one
  • (S)-2-(2,4-Dihydroxyphenyl)-7-hydroxy-5-methoxy-8-((R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl)chroman-4-one
  • 34981-26-5
  • 18837-52-8