PROTEIN TYROSINE PHOSPHATASE 1B

Product Name: PROTEIN TYROSINE PHOSPHATASE 1B
Chemical Name: PROTEIN TYROSINE PHOSPHATASE 1B
Synonyms: PTPN1;PTP1B;PTP-1B, AGAROSE;Human PTPN1 Protein, His Tag;PTP1B full length Active human;PROTEIN TYROSINE PHOSPHATASE 1B;PTP1B (1-321)/PTPN1 Active human;PTP1B (1-321)/PTPN1 Active from rat;PROTEIN TYROSINE PHOSPHATASE 1B HUMAN;PTP1B (1-321)/PTPN1 Active from mouse
CBNumber: CB5237056
Formula Weight: 0
MOL File: Mol file

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PROTEIN TYROSINE PHOSPHATASE 1B Property

storage temp.: −70°C
form: buffered aqueous solution
biological source: rabbit
Specific Activity: ≥20units/mg protein

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Safety

WGK Germany: 1
HS Code: 3504009000
Storage Class: 10 - Combustible liquids

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SRP0215
Product name: PTP1B full length Active human
Purity: recombinant, expressed in E. coli, ≥55% (SDS-PAGE)
Packaging: 20μG
Price: $531
Updated: 2026/03/19

Sigma-Aldrich

Product number: SRP0215
Product name: PTP1B full length Active human
Purity: recombinant, expressed in <I>E. coli</I>, ≥55% (SDS-PAGE), aqueous solution
Packaging: 50 μg
Price: $739
Updated: 2026/03/19

Sigma-Aldrich

Product number: SRP0212
Product name: PTP1B (1-321)/PTPN1 Active human
Purity: recombinant, expressed in <I>E. coli</I>, ≥90% (SDS-PAGE)
Packaging: 50 μg
Price: $542
Updated: 2026/03/19

Sigma-Aldrich

Product number: SRP0212
Product name: PTP1B (1-321)/PTPN1 Active human
Purity: recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Packaging: 20μG
Price: $560
Updated: 2026/03/19

Sigma-Aldrich

Product number: SAB4502525
Product name: Anti-PTP1B antibody produced in rabbit
Purity: affinity isolated antibody
Packaging: 100μg
Price: $560
Updated: 2026/03/19

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PROTEIN TYROSINE PHOSPHATASE 1B Chemical Properties,Usage,Production

Uses

Protein Tyrosine Phosphatase 1B (PTP1B) human has been used in treating cell lysate prior to immunoprecipitation and protein pull-down studies. It has also been used in PTP1B activity assay and also for the evaluation of inhibitors like betulinic acid (BA) and sodium orthovanadate (Na3VO4), and 6-chloro-3-formyl-7-methylchromone (CFM) on PTP1B.

General Description

Protein tyrosine phosphatase 1B human (PTP1B) is encoded by the gene PTPN1. In human chromosome, the gene PTPN1 is localized on 20q13.13. The protein has 37 kDa catalytic domain and the C-terminal hydrophobic residues targets the protein to the cytoplasmic side of the endoplasmic reticulum membrane.

Biochem/physiol Actions

PTP-1B is a recombinant, non-transmembrane protein expressed in E. coli containing amino acid residues 1-322 of human PTP-1B. It has a molecular mass of 37.4 kDa. It is an abundant intracellular enzyme that is thought to act as a negative regulator of certain signaling pathways. It dephosphorylates tyrosine-phosphorylated proteins and peptides, and is usually localized in the cytostolic domain of the ER.

PROTEIN TYROSINE PHOSPHATASE 1B Preparation Products And Raw materials

Raw materials

Preparation Products

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PROTEIN TYROSINE PHOSPHATASE 1B Suppliers

China 38 Japan 1 Switzerland 1 United Kingdom 2 United States 4 Global 46

Sigma-Aldrich

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ACROBiosystems

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Enzo Biochem Inc

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Merck KGaA

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Signalway Antibody LLC

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Beijing Biosynthesis Biotechnology Co Ltd

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Shanghai Yubo Biotechnology Co., Ltd

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PROTEIN TYROSINE PHOSPHATASE 1BRelated Search:

gp330 Huntingtin Sorbitol-Maconkey agar base FCGR3A Fibronectin Protein H-2Db&B2M Microfibrillar-associated protein 5 EC 2.6.1.2 Cathepsin E E8L (MPXV)

ANTI-PTP1B antibody produced in rabbit

MONOCLONAL ANTI-PTP1B antibody produced in mouse

ANTI-PTP1B (N-TERMINAL) antibody produced in rabbit

PROTEIN TYROSINE PHOSPHATASE 1B, HUMAN, RECOMBINANT, E COLI

PROTEIN TYROSINE PHOSPHATASE 1B HUMAN

PROTEIN TYROSINE PHOSPHATASE 1B

PTP1B

PTP-1B, AGAROSE

PROTEIN TYROSINE PHOSPHATASE 1B, AGAROSE

Recombinant Human Protein Tyrosine Phosphatase 1B

PTPN1

Tyrosine-protein phosphatase non-receptor type 1

PTP1B full length Active human

PTP1B (1-321)/PTPN1 Active from rat

PTP1B (1-321)/PTPN1 Active human

Protein tyrosine phosphatase, non-receptor type 1

PTP1B (1-321)/PTPN1 Active from mouse

Human PTPN1 Protein, His Tag

BioChemical

Cell Signaling and Neuroscience

Cell Biology

Tyrosine Phosphatases

Tyrosine Phosphatase (TP)

Kinase/Phosphatase Biology

protein kinase