ETHYL 2-(3-BROMOPHENYL)ACETATE
- Product Name
- ETHYL 2-(3-BROMOPHENYL)ACETATE
- CAS No.
- 14062-30-7
- Chemical Name
- ETHYL 2-(3-BROMOPHENYL)ACETATE
- Synonyms
- Ethyl 2-(3-bromophenyl);Ethyl 3-Bromophenylacetate;ETHYL 2-(3-BROMOPHENYL)ACETATE;Benzeneacetic acid, 3-broMo-, ethyl ester
- CBNumber
- CB52453193
- Molecular Formula
- C10H11BrO2
- Formula Weight
- 243.1
- MOL File
- 14062-30-7.mol
ETHYL 2-(3-BROMOPHENYL)ACETATE Property
- Boiling point:
- 132-134 °C(Press: 8 Torr)
- Density
- 1.3810 g/cm3
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Oil
- color
- Colourless
Safety
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B124678
- Product name
- Ethyl2-(3-Bromophenyl)acetate
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 078862
- Product name
- Ethyl3-bromophenylacetate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $12
- Updated
- 2021/12/16
- Product number
- J94756
- Product name
- Ethyl3-Bromophenylacetate
- Packaging
- 5g
- Price
- $32
- Updated
- 2021/12/16
- Product number
- FB61410
- Product name
- Ethyl 3-Bromophenylacetate
- Packaging
- 2g
- Price
- $40
- Updated
- 2021/12/16
- Product number
- 075367
- Product name
- Ethyl 3-bromophenylacetate
- Purity
- 95+%
- Packaging
- 5g
- Price
- $44
- Updated
- 2021/12/16
ETHYL 2-(3-BROMOPHENYL)ACETATE Chemical Properties,Usage,Production
Synthesis Reference(s)
Journal of Medicinal Chemistry, 43, p. 1508, 2000 DOI: 10.1021/jm990448e
Synthesis
64-17-5
1878-67-7
14062-30-7
To a 250 mL round bottom flask was added 3-bromophenylacetic acid (5 g, 23.25 mmol, 1.00 equiv) and ethanol (80 mL). With stirring at 0 °C, thionyl chloride (5.6 g, 46.28 mmol, 2.00 eq.) was added slowly and dropwise. The reaction mixture was heated to reflux and kept for 2 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure to remove the solvent. Subsequently, the reaction was quenched by the addition of water. The aqueous phase was extracted with ethyl acetate (3 × 30 mL) and the organic layers were combined. The organic layer was washed with saturated saline (50 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. 5.5 g (97% yield) of ethyl 2-(3-bromophenyl)acetate was finally obtained as a colorless oil.
References
[1] Journal of Medicinal Chemistry, 2000, vol. 43, # 8, p. 1508 - 1518
[2] Patent: US2013/190290, 2013, A1. Location in patent: Paragraph 1328; 1329; 1330
[3] Patent: WO2015/130957, 2015, A1. Location in patent: Page/Page column 77
[4] Patent: WO2010/127440, 2010, A1. Location in patent: Page/Page column 39-40
[5] Patent: WO2010/127448, 2010, A1. Location in patent: Page/Page column 26-27
ETHYL 2-(3-BROMOPHENYL)ACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
ETHYL 2-(3-BROMOPHENYL)ACETATE Suppliers
- Tel
- --
- Fax
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- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6005
- Advantage
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View Lastest Price from ETHYL 2-(3-BROMOPHENYL)ACETATE manufacturers
- Product
- ETHYL 2-(3-BROMOPHENYL)ACETATE 14062-30-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-25