ChemicalBook > CAS DataBase List > (3-BROMOPHENYL)ACETIC ACID METHYL ESTER

(3-BROMOPHENYL)ACETIC ACID METHYL ESTER

Product Name
(3-BROMOPHENYL)ACETIC ACID METHYL ESTER
CAS No.
150529-73-0
Chemical Name
(3-BROMOPHENYL)ACETIC ACID METHYL ESTER
Synonyms
Methyl 3-bromophenylacetate;Methyl3-bromophenylacetate98%;Methyl 3-bromophenylacetate 98%;METHYL 2-(3-BROMOPHENYL)ACETATE;methyl 2-(3-bromophenyl)acetatee;Methyl 2-(3-bromophenyl)acetate, 97%;(3-BROMOPHENYL)ACETIC ACID METHYL ESTER;Benzeneacetic acid, 3-bromo-, methyl ester;3-Bromophenylacetic acid methyl ester, Methyl 2-(3-bromophenyl)ethanoate
CBNumber
CB2357050
Molecular Formula
C9H9BrO2
Formula Weight
229.07
MOL File
150529-73-0.mol
More
Less

(3-BROMOPHENYL)ACETIC ACID METHYL ESTER Property

Boiling point:
268.6±15.0 °C(Predicted)
Density 
1.445±0.06 g/cm3(Predicted)
refractive index 
1.5440 to 1.5480
storage temp. 
Sealed in dry,Room Temperature
form 
clear liquid
color 
Colorless to Almost colorless
More
Less

Safety

Hazard Codes 
Xi
Hazard Note 
Harmful/Irritant/Keep Cold
HS Code 
2916399090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
M2804
Product name
Methyl 3-Bromophenylacetate
Purity
>98.0%(GC)
Packaging
5g
Price
$77
Updated
2025/07/31
TCI Chemical
Product number
M2804
Product name
Methyl 3-Bromophenylacetate
Purity
>98.0%(GC)
Packaging
25g
Price
$230
Updated
2025/07/31
TRC
Product number
M294990
Product name
Methyl2-(3-bromophenyl)acetate
Packaging
100g
Price
$1210
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0026277
Product name
METHYL 2-(3-BROMOPHENYL)ACETATE
Purity
95.00%
Packaging
25G
Price
$1432.43
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0026277
Product name
METHYL 2-(3-BROMOPHENYL)ACETATE
Purity
95.00%
Packaging
1G
Price
$599.33
Updated
2021/12/16
More
Less

(3-BROMOPHENYL)ACETIC ACID METHYL ESTER Chemical Properties,Usage,Production

Uses

Methyl 2-(3-bromophenyl)acetate is used as a reagent to synthesize the methyl ester derivative of (R)-Flurbiprofen (F598730). (R)-Flurbiprofen is a nonsteroidal anti-inflammatory drug that exists as a racemate and also has potential application as a treatment for patients with Alzheimer’s Disease.

Synthesis

67-56-1

1878-67-7

150529-73-0

General procedure for the synthesis of methyl (3-bromophenyl)acetate from methanol and 3-bromophenylacetic acid: acetyl chloride (0.08 mL, 1.2 mmol, 0.5 eq.) and 3-bromophenylacetic acid (0.5 g, 2.3 mmol, 1.0 eq.) were added to methanol (10 mL), and the reaction mixture was refluxed for 2 hours. Upon completion of the reaction, the consumption of starting material was confirmed by TLC monitoring. The reaction mixture was concentrated and extracted with dichloromethane (DCM). The organic phases were combined, washed with saturated brine, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford methyl (3-bromophenyl)acetate as a colorless oil (0.525 g, 98.7% yield). The product was analyzed by LC-MS (ES), m/z = 229.0, 231.0 [M + H]+. 1H NMR (400 MHz, DMSO-d6) δ 3.61 (s, 3H), 3.70 (s, 2H), 7.26-7.30 (m, 2H), 7.43-7.46 (m, 1H), 7.48 (s, 1H).

References

[1] Bioorganic and Medicinal Chemistry, 2003, vol. 11, # 13, p. 2843 - 2866
[2] Journal of Medicinal Chemistry, 2008, vol. 51, # 3, p. 392 - 395
[3] Patent: EP1479681, 2004, A1. Location in patent: Page 111; 112
[4] Patent: US2007/3539, 2007, A1. Location in patent: Page/Page column 96
[5] Journal of Medicinal Chemistry, 1995, vol. 38, # 26, p. 4976 - 4984

(3-BROMOPHENYL)ACETIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(3-BROMOPHENYL)ACETIC ACID METHYL ESTER Suppliers

Americas 1 China 124 Europe 1 Germany 1 India 13 Japan 1 United Kingdom 3 United States 21 Global 165
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Changzhou Huanling Chemical Co., Ltd.
Tel
0519-89803565 13776850645
Fax
0519-89803575
Email
info4@huanlingchem.com
Country
China
ProdList
891
Advantage
68
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Tetranov Biopharm
Tel
13526569071
Email
sales@leadmedpharm.com
Country
China
ProdList
7892
Advantage
64
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
More
Less

View Lastest Price from (3-BROMOPHENYL)ACETIC ACID METHYL ESTER manufacturers

Career Henan Chemical Co
Product
(3-BROMOPHENYL)ACETIC ACID METHYL ESTER 150529-73-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000KGS
Release date
2020-01-02

150529-73-0, (3-BROMOPHENYL)ACETIC ACID METHYL ESTERRelated Search:

METHYL 2-(2-BROMOPHENYL)ACETATE 4-BROMOPHENYL ACETIC ACID METHYL ESTER METHYL ALPHA-BROMOPHENYLACETATE 3-Bromophenylacetic acid 3(3'-BROMOPHENYL)-6-CHLORO-4,7-DIMETHYLCOUMARIN 3(3'-BROMOPHENYL)-7-HYDROXY-4-METHYLCOUMARIN 3(3'-BROMOPHENYL)-4,6-DIMETHYLCOUMARIN 3(3'-BROMOPHENYL)COUMARIN 7-ALLYLOXY-3(3'-BROMOPHENYL)-4-PHENYL COUMARIN 6-BROMO-3(3'-BROMOPHENYL)-8-CHLORO-4-METHYLCOUMARIN 3(3'-BROMOPHENYL)-4-PHENYLCOUMARIN 3(3'-BROMOPHENYL)-7-HYDROXYCOUMARIN 3(3'-BROMOPHENYL)-7-METHOXY-4-METHYLCOUMARIN 6-BROMO-3(3'-BROMOPHENYL)-4-METHYLCOUMARIN 3(3'-BROMOPHENYL)-6-METHYL-4-PHENYLCOUMARIN 3(3'-BROMOPHENYL)-7-METHYL-4-PHENYLCOUMARIN 3(3'-BROMOPHENYL)-6,8-DICHLORO-4-METHYLCOUMARIN 8-BROMO-3(3'-BROMOPHENYL)-6-CHLORO-4-METHYLCOUMARIN

  • (3-BROMOPHENYL)ACETIC ACID METHYL ESTER
  • Methyl 3-bromophenylacetate 98%
  • Methyl 3-bromophenylacetate
  • 3-Bromophenylacetic acid methyl ester, Methyl 2-(3-bromophenyl)ethanoate
  • Methyl3-bromophenylacetate98%
  • METHYL 2-(3-BROMOPHENYL)ACETATE
  • methyl 2-(3-bromophenyl)acetatee
  • Benzeneacetic acid, 3-bromo-, methyl ester
  • Methyl 2-(3-bromophenyl)acetate, 97%
  • 150529-73-0
  • blocks
  • Bromides
  • Carboxes
  • pharmacetical