METHYL 2-(2-BROMOPHENYL)ACETATE

Product Name: METHYL 2-(2-BROMOPHENYL)ACETATE
CAS No.: 57486-69-8
Chemical Name: METHYL 2-(2-BROMOPHENYL)ACETATE
Synonyms: 2-broMobenzyl acetate;Methyl 2-bromophenylacetate;Methyl 2-(2-bromophenyl);Methyl o-bromophenylacetate;Methyl 2-bromobenzeneacetate;(2-BroMophenyl)Methyl acetate;METHYL 2-(2-BROMOPHENYL)ACETATE;Methyl 2-bromophenylacetate 98%;2-(2-bromophenyl) methyl acetate;Methyl 2-(2-bromophenyl)acetate 98%
CBNumber: CB9346695
Molecular Formula: C9H9BrO2
Formula Weight: 229.07
MOL File: 57486-69-8.mol

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METHYL 2-(2-BROMOPHENYL)ACETATE Property

Boiling point:: 264℃
Density: 1.445
Flash point:: 114℃
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
form: liquid
color: Pale yellow
InChI: InChI=1S/C9H9BrO2/c1-12-9(11)6-7-4-2-3-5-8(7)10/h2-5H,6H2,1H3
InChIKey: AMVCFIFDMKEIRE-UHFFFAOYSA-N
SMILES: C1(CC(OC)=O)=CC=CC=C1Br

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Safety

Hazard Codes: Xi
Hazard Note: Irritant/Keep Cold
HS Code: 2916399090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC

Product number: M295210
Product name: Methyl2-(2-Bromophenyl)acetate
Packaging: 1g
Price: $95
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2723-9-X6
Product name: Methyl 2-(2-bromophenyl)acetate
Purity: 98%
Packaging: 5G
Price: $24
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2723-9-X6
Product name: Methyl 2-(2-bromophenyl)acetate
Purity: 98%
Packaging: 25g
Price: $68
Updated: 2021/12/16

AK Scientific

Product number: B229
Product name: Methyl2-(2-bromophenyl)acetate
Packaging: 100g
Price: $227
Updated: 2021/12/16

Matrix Scientific

Product number: 129845
Product name: (2-Bromo-phenyl)-aceticacidmethylester
Purity: 95%+
Packaging: 1g
Price: $234
Updated: 2021/12/16

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METHYL 2-(2-BROMOPHENYL)ACETATE Chemical Properties,Usage,Production

Uses

Methyl 2-(2-bromophenyl)acetate is a reagent in the synthesis of 2,3,3a,12b-Tetradehydro Asenapine (T291630). 2,3,3a,12b-Tetradehydro Asenapine is a degredation product of Asenapine (A788000), a combined serotonin (5HT2) and dopamine (D2) receptor antagonist; structurally related to Mianserin. Antipsychotic.

Synthesis

67-56-1

18698-97-0

57486-69-8

General method: o-Bromophenylacetic acid (5.0 g, 18.18 mmol) was dissolved in methanol (50 mL) containing a catalytic amount of concentrated sulfuric acid and the reaction was refluxed for 30 minutes. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure to remove the solvent. Water (30 mL) was added to the residue, which was subsequently extracted with dichloromethane (3 x 20 mL). The organic layers were combined, dried over anhydrous sodium sulfate and the solvent was evaporated under reduced pressure to give the corresponding methyl 2-(2-bromophenyl)acetate products. The products were: methyl 2-(2-bromo-4,5-dimethoxyphenyl)acetate (S5a, 5.19 g, 99%, brown oil); methyl 2-(2-bromo-5-methoxyphenyl)acetate (S5b, 2.09 g, 99%, brown oil); methyl 2-(2-bromo-4-methoxyphenyl)acetate (S5c, 2.09 g, 99%, brown oil ); methyl 2-(2-bromophenyl)acetate (S5d, 5.27g, 99%, clear oil).

References

[1] Journal of the American Chemical Society, 2003, vol. 125, # 11, p. 3268 - 3272
[2] Chemistry - An Asian Journal, 2011, vol. 6, # 8, p. 2040 - 2047
[3] Tetrahedron, 2013, vol. 69, # 42, p. 8914 - 8920
[4] Chemistry - A European Journal, 2016, vol. 22, # 34, p. 12166 - 12175
[5] Tetrahedron Letters, 2003, vol. 44, # 2, p. 331 - 334

METHYL 2-(2-BROMOPHENYL)ACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL 2-(2-BROMOPHENYL)ACETATE Suppliers

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View Lastest Price from METHYL 2-(2-BROMOPHENYL)ACETATE manufacturers

Career Henan Chemical Co

Product: METHYL 2-(2-BROMOPHENYL)ACETATE 57486-69-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-08

57486-69-8, METHYL 2-(2-BROMOPHENYL)ACETATERelated Search:

METHYL 2-(3-BROMOPHENYL)ACETATE METHYL ALPHA-BROMO-2-CHLOROPHENYLACETATE Ethyl 2-(2-bromophenyl)acetate METHYL 2-(2-BROMOPHENYL)ACETATE METHYL 2-(4-BROMOPHENYL)ACETATE METHYL ALPHA-BROMOPHENYLACETATE Methyl phenylacetate AMINO-(2-BROMO-PHENYL)-ACETIC ACID METHYL ESTER HYDROCHLORIDE METHYL-2-BROMO-4-METHOXYPHENYLACETATE methyl amino(3-bromophenyl)acetate hydrochloride AKOS AU36-M258 AKOS AU36-M434 AKOS AU36-M435 2-BROMO-3-CHLOROPHENYLACETIC ACID METHYL ESTER AURORA KA-7913 AKOS AU36-M431 RARECHEM AK ML 0189 AKOS AU36-M430

Methyl o-bromophenylacetate

2-broMobenzyl acetate

Methyl 2-(2-bromophenyl)

(2-BROMO-PHENYL)-ACETIC ACID METHYL ESTER

Methyl 2-bromophenylacetate

METHYL 2-(2-BROMOPHENYL)ACETATE

Methyl 2-(2-bromophenyl)acetate 98%

Benzeneacetic acid,2-bromo-, methyl ester

Methyl 2-bromophenylacetate 98%

(2-BroMophenyl)Methyl acetate

2-Bromobenzeneacetic acid methyl ester

Methyl 2-bromobenzeneacetate

2-(2-bromophenyl) methyl acetate

57486-69-8

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