ETHYL IMIDAZO[1,5-A]PYRIDINE-3-CARBOXYLATE
- Product Name
- ETHYL IMIDAZO[1,5-A]PYRIDINE-3-CARBOXYLATE
- CAS No.
- 81803-60-3
- Chemical Name
- ETHYL IMIDAZO[1,5-A]PYRIDINE-3-CARBOXYLATE
- Synonyms
- ethyl imidazo(1,5)-pyridine-3-carboxylate;Ethyl 3-Imidazo[1,5-a]pyridinecarboxylate;ETHYL IMIDAZO[1,5-A]PYRIDINE-3-CARBOXYLATE;ethyl 1H-imidazo[1,5-a]pyridine-3-carboxylate;Imidazo[1,5-a]pyridine-3-carboxylic acid ethyl ester
- CBNumber
- CB52454620
- Molecular Formula
- C10H10N2O2
- Formula Weight
- 190.2
- MOL File
- 81803-60-3.mol
ETHYL IMIDAZO[1,5-A]PYRIDINE-3-CARBOXYLATE Property
- Density
- 1.22±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 3.98±0.30(Predicted)
- Appearance
- Light yellow to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- E940180
- Product name
- EthylImidazo[1,5-A]pyridine-3-carboxylate
- Packaging
- 500mg
- Price
- $285
- Updated
- 2021/12/16
- Product number
- CHM0392644
- Product name
- ETHYL IMIDAZO[1,5-A]PYRIDINE-3-CARBOXYLATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.93
- Updated
- 2021/12/16
- Product number
- CM123865
- Product name
- ethylimidazo[1,5-a]pyridine-3-carboxylate
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $54
- Updated
- 2021/12/16
- Product number
- CM123865
- Product name
- ethylimidazo[1,5-a]pyridine-3-carboxylate
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $69
- Updated
- 2021/12/16
- Product number
- CM123865
- Product name
- ethylimidazo[1,5-a]pyridine-3-carboxylate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $206
- Updated
- 2021/12/16
ETHYL IMIDAZO[1,5-A]PYRIDINE-3-CARBOXYLATE Chemical Properties,Usage,Production
Synthesis
46460-25-7
81803-60-3
General procedure for the synthesis of ethyl imidazo[1,5-a]pyridine-3-carboxylate from ethyl 2-oxo-2-((pyridin-2-ylmethyl)amino)acetate: ethyl [(pyridin-2-ylmethyl)carbamoyl]formate (1.00 g, 4.80 mmol, 1.00 equiv) and phosphorus pentoxide (3.41 g, 24.02 mmol, 5.00 equiv) were dissolved in phosphoryl chloride (30 mL). ) were dissolved in phosphoryl chloride (30 mL) and the reaction was stirred at 110°C for 5 hours. After completion of the reaction, the mixture was concentrated under reduced pressure. The residue was purified by silica gel column chromatography with ethyl acetate/petroleum ether (1:1, v/v) as eluent. 635 mg (70% yield) of the target product, ethyl imidazo[1,5-a]pyridine-3-carboxylate, was finally obtained as a yellow solid.LC-MS (ESI, m/z): 191 [M + H]+.
References
[1] Patent: WO2015/25025, 2015, A1. Location in patent: Page/Page column 411; 412
[2] Patent: WO2008/85302, 2008, A1. Location in patent: Page/Page column 96
[3] Organic Letters, 2013, vol. 15, # 9, p. 2290 - 2293
[4] Synthesis (Germany), 2016, vol. 48, # 23, p. 4269 - 4277
ETHYL IMIDAZO[1,5-A]PYRIDINE-3-CARBOXYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
ETHYL IMIDAZO[1,5-A]PYRIDINE-3-CARBOXYLATE Suppliers
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