ChemicalBook > CAS DataBase List > PYRAZOLO[1,5-A]PYRIMIDINE

PYRAZOLO[1,5-A]PYRIMIDINE

Product Name
PYRAZOLO[1,5-A]PYRIMIDINE
CAS No.
274-71-5
Chemical Name
PYRAZOLO[1,5-A]PYRIMIDINE
Synonyms
pyrazolo[2,3-a]pyrimidine;PYRAZOLO[1,5-A]PYRIMIDINE;Pyrazolo[1,5-a]pyrimidine (8CI, 9CI, ACI)
CBNumber
CB52454983
Molecular Formula
C6H5N3
Formula Weight
119.12
MOL File
274-71-5.mol
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PYRAZOLO[1,5-A]PYRIMIDINE Property

Melting point:
105 °C
Density 
1.29±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
0.33±0.30(Predicted)
Appearance
White to off-white Solid
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Safety

Risk Statements 
20/21/22
Safety Statements 
36/37
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
P846520
Product name
Pyrazolo[1,5-a]pyrimidine
Packaging
100mg
Price
$60
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0096801
Product name
PYRAZOLO[1,5-A]PYRIMIDINE
Purity
95.00%
Packaging
1G
Price
$1024.78
Updated
2021/12/16
AK Scientific
Product number
X7988
Product name
Pyrazolo[1,5-a]pyrimidine
Packaging
5g
Price
$351
Updated
2021/12/16
Apolloscientific
Product number
OR301222
Product name
Pyrazolo[1,5-a]pyrimidine
Purity
98%
Packaging
1g
Price
$95
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-1-32
Product name
Pyrazolo[1,5-a]pyrimidine
Purity
96%
Packaging
1g
Price
$104
Updated
2021/12/16
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PYRAZOLO[1,5-A]PYRIMIDINE Chemical Properties,Usage,Production

Chemical Properties

Light yellow solid

Uses

Pyrazolo[1,5-a]pyrimidine is being researched as a protein kinase CK2 inhibitors.

Synthesis

1820-80-0

927-63-9

274-71-5

Preparation of compound 23a: 1H-pyrazol-3-ylamine (32 g, 0.386 mol) and (E)-3-dimethylaminoacrylaldehyde (38.2 g, 0.386 mol) were dissolved in ethanol (500 mL), and the reaction was carried out at reflux for 6 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure and the resulting residue was purified by column chromatography (eluent: petroleum ether/ethyl acetate = 10:1 to 2:1) to afford the target product, pyrazolo[1,5-a]pyrimidine 23a, as a white solid (30 g, 65% yield).

References

[1] Synthesis, 2006, # 1, p. 59 - 62
[2] Patent: WO2010/16005, 2010, A1. Location in patent: Page/Page column 116

PYRAZOLO[1,5-A]PYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from PYRAZOLO[1,5-A]PYRIMIDINE manufacturers

Career Henan Chemical Co
Product
PYRAZOLO[1,5-A]PYRIMIDINE 274-71-5
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
200kg
Release date
2018-12-24

274-71-5, PYRAZOLO[1,5-A]PYRIMIDINERelated Search:

PYRAZOLO[1,5-A]PYRIMIDINE-5-CARBOXYLICACID PYRAZOLO[1,5-A]PYRIDIN-2-OL 5-Hydroxypyrazolo[1,5-a]pyrimidine PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID ETHYL ESTER PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBONITRILE C-PYRAZOLO[1,5-A]PYRIDIN-7-YL-METHYLAMINE Pyrazolo[1,5-a]pyridine PYRAZOLO[1,5-A]PYRIDINE-2-CARBOXYLIC ACID AMIDE Pyrazolam 1H-Pyrrolo[2,3-c]pyridin-7-amine(9CI) 4,7-DIMETHYLPYRAZOLO(1,5-A)PYRIMIDINE-3-CARBOXYLIC ACID PYRAZOPHOS 1-[2-(4-CHLOROPHENYL)-7-METHYLPYRAZOLO[1,5-A]PYRIMIDIN-6-YL]ETHAN-1-ONE 6-(TERT-BUTYLSULFONYL)-2-METHYLPYRAZOLO[1,5-A]PYRIMIDIN-7-AMINE 7-Aminopyrazolo[1,5-a]pyrimidine-6-carbonitrile ETHYL 7-METHYL-2-(2-THIENYL)PYRAZOLO[1,5-A]PYRIMIDINE-6-CARBOXYLATE 7-PHENYLPYRAZOLO[1,5-A]PYRIMIDINE-3-CARBONITRILE ETHYL 7-METHYL-2-PHENYLPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBOXYLATE

  • PYRAZOLO[1,5-A]PYRIMIDINE
  • pyrazolo[2,3-a]pyrimidine
  • Pyrazolo[1,5-a]pyrimidine (8CI, 9CI, ACI)
  • 274-71-5