ChemicalBook > CAS DataBase List > 5-METHOXYGRAMINE

5-METHOXYGRAMINE

Product Name
5-METHOXYGRAMINE
CAS No.
16620-52-3
Chemical Name
5-METHOXYGRAMINE
Synonyms
NSC 88885;methoxygramine;5-METHOXYGRAMINE;TIMTEC-BB SBB003509;5-METHOXYGRAMINE 99%;5-Methoxygramine,99%;3-ETHYL-1H-PYRAZOL-5-AMINE HCL;2-dimethylaminomethyl-5-methoxyindole;5-methoxy-3-(dimethylaminomethyl)indole;3-(DIMETHYLAMINOMETHYL)-5-METHOXY-INDOLE
CBNumber
CB5245525
Molecular Formula
C12H16N2O
Formula Weight
204.27
MOL File
16620-52-3.mol
More
Less

5-METHOXYGRAMINE Property

Melting point:
123-126 °C (lit.)
Boiling point:
342.77°C (rough estimate)
Density 
1.0565 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
Refrigerator (+4°C)
pka
16.70±0.30(Predicted)
BRN 
170533
CAS DataBase Reference
16620-52-3(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
C,Xi
Risk Statements 
34-22
Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
NL7700000
F 
10
HS Code 
29339900
Toxicity
mouse,LD50,intraperitoneal,130mg/kg (130mg/kg),Psychopharmacologia Vol. 16, Pg. 385, 1970.
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M14870
Product name
5-Methoxygramine
Purity
99%
Packaging
5g
Price
$225
Updated
2023/06/20
TRC
Product number
M263278
Product name
5-Methoxygramine
Packaging
10mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
Y7751
Product name
N-[(5-Methoxy-1H-indol-3-yl)methyl]-N,N-dimethylamine
Packaging
1g
Price
$104
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0031161
Product name
5-METHOXYGRAMINE
Purity
95.00%
Packaging
1G
Price
$654.89
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0031161
Product name
5-METHOXYGRAMINE
Purity
95.00%
Packaging
5G
Price
$970.2
Updated
2021/12/16
More
Less

5-METHOXYGRAMINE Chemical Properties,Usage,Production

Chemical Properties

white to almost white crystalline powder

Uses

• ;Reactant for preparation of dopamine D2 receptor antagonists1• ;Reactant for asymmetric preparation of ethenyl(tetrahydro)carbazoledicarboxylates via gold(I)-catalyzed intramolecular Friedel-Crafts allylic alkylation reaction2• ;Reactant for preparation of N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ols as dopamine D2-like receptor ligands3• ;Reactant for preparation of substituted N-trimethoxybenzoyl indoles, indolines, and a tetrahydroquinoline via N-aroylation with trimethoxybenzoyl chloride or anhydride as antitubulin agents4• ;Reactant for preparation of in

Uses

  • Reactant for preparation of dopamine D2 receptor antagonists
  • Reactant for asymmetric preparation of ethenyl(tetrahydro)carbazoledicarboxylates via gold(I)-catalyzed intramolecular Friedel-Crafts allylic alkylation reaction
  • Reactant for preparation of N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ols as dopamine D2-like receptor ligands
  • Reactant for preparation of substituted N-trimethoxybenzoyl indoles, indolines, and a tetrahydroquinoline via N-aroylation with trimethoxybenzoyl chloride or anhydride as antitubulin agents
  • Reactant for preparation of indolylmethanesulfonamide and its methoxy derivatives

5-METHOXYGRAMINE Preparation Products And Raw materials

Raw materials

5-Methoxyindole Formaldehyde Diethyl ether Hydrochloric acid Acetic acid Sodium hydroxide Dimethylamine

Preparation Products

More
Less

5-METHOXYGRAMINE Suppliers

Belgium 2 China 29 Germany 1 India 1 Japan 1 South Korea 1 Switzerland 3 United Kingdom 8 United States 16 Global 62
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71

16620-52-3, 5-METHOXYGRAMINERelated Search:

Gramine 4-Methoxygramine 6-METHOXYGRAMINE 5-BENZYLOXYGRAMINE 3-DIMETHYLAMINOMETHYL-5-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID ETHYL ESTER 2-ACETYL-8-TRIFLUOROMETHOXY-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE (5-METHOXY-1H-INDOL-3-YL)(PIPERIDINO)METHANETHIONE Oxybis((5,3-indolylene)methylene)bis(trimethylammonium) bis(methyl sul fate) 5-METHOXY-2-METHYLGRAMINE 5-ETHYL-2-(5-METHOXY-1H-INDOL-3-YL)-7-METHYL-1,3-DIAZATRICYCLO[3.3.1.1~3,7~]DECAN-6-ONE 5-METHOXYGRAMINE 8-BENZYLOXY-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE AKOS JY2083007 2-ACETYL-8-METHOXY-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE 1-[(5-methoxy-1H-indol-3-yl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxylic acid AKOS JY2083279

  • 5-METHOXYGRAMINE 99%
  • 5-Methoxygramine, N,N-Dimethyl-(5-methoxy-1H-indol-3-yl)methylamine
  • methoxygramine
  • 5-Methoxygramine or 5-Methoxy-3-(Dimethylaminomethyl)-indole
  • (5-methoxy-1H-indol-3-yl)methyl-dimethylammonium
  • 3-ETHYL-1H-PYRAZOL-5-AMINE HCL
  • 5-Methoxygramine,99%
  • NSC 88885
  • 3-((dimethylamino)methyl)-5-methoxy-indol
  • 5-methoxy-3-(dimethylaminomethyl)indole
  • 5-methoxy-n,n-dimethyl-1h-indole-3-methanamin
  • TIMTEC-BB SBB003509
  • 3-[(Dimethylamino)methyl]-5-methoxy-1H-indole
  • 3-(DIMETHYLAMINOMETHYL)-5-METHOXY-INDOLE
  • (5-METHOXY-1H-INDOL-3-YLMETHYL)-DIMETHYL-AMINE
  • 5-METHOXYGRAMINE
  • 2-dimethylaminomethyl-5-methoxyindole
  • N-[(5-METHOXY-1H-INDOL-3-YL)METHYL]-N,N-DIMETHYLAMINE
  • 1H-Indole-3-methanamine, 5-methoxy-N,N-dimethyl-
  • 16620-52-3
  • Heterocyclic Building Blocks
  • Indoles
  • Building Blocks
  • Building Blocks
  • C12
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Indoles
  • Indoline & Oxindole
  • Heterocyclic Compounds
  • Indoles and derivatives