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PI 828

Product Name
PI 828
CAS No.
942289-87-4
Chemical Name
PI 828
Synonyms
PI 828;PI 828,PI828;LY 294002, 4′-NH2;LY 294002, 4-NH - CAS 942289-87-4 - Calbiochem;8-(4-aminophenyl)-2-morpholin-4-ylchromen-4-one;8-(4-Aminophenyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one;2-(4-Morpholinyl)-8-(4-aminopheny)l-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 8-(4-aminophenyl)-2-(4-morpholinyl)-
CBNumber
CB52455753
Molecular Formula
C19H18N2O3
Formula Weight
322.36
MOL File
942289-87-4.mol
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PI 828 Property

Boiling point:
534.2±50.0 °C(Predicted)
Density 
1.316±0.06 g/cm3(Predicted)
storage temp. 
Store at +4°C
solubility 
DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: slightly soluble
pka
4.14±0.10(Predicted)
form 
Off-white solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
440206
Product name
LY 294002, 4-NH - CAS 942289-87-4 - Calbiochem<br />A cell-permeable LY 294002 4'-amino derivative with enhanced potency against p110α/β/δ/γ.
Packaging
5mg
Price
$251
Updated
2023/01/07
Cayman Chemical
Product number
21811
Product name
PI-828
Purity
≥98%
Packaging
1mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
21811
Product name
PI-828
Purity
≥98%
Packaging
5mg
Price
$135
Updated
2024/03/01
Cayman Chemical
Product number
21811
Product name
PI-828
Purity
≥98%
Packaging
10mg
Price
$235
Updated
2024/03/01
Tocris
Product number
2814
Product name
PI828
Purity
≥98%(HPLC)
Packaging
1
Price
$106
Updated
2021/12/16
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PI 828 Chemical Properties,Usage,Production

Definition

ChEBI: 8-(4-aminophenyl)-2-(4-morpholinyl)-1-benzopyran-4-one is a member of chromones.

General Description

A cell-permeable LY 294002 (Cat. Nos. 440202 & 440204) 4′-amino derivative with enhanced potency against p110α/β/δ/γ (IC50 in nM/-fold increase in potency = 183/2.7-, 98/5.7-, 1227/.5-, and 1967/1.9-, respectively). The molecule has been immobilized on epoxy-containing solid surface via the 4′-amine for binding studies and shown to interact with non-PI3K cellular proteins, such as mTOR, ALDH1, Brd4, GSK3β, and CKIIα.

Biological Activity

PI 3-Kinase inhibitor (IC 50 values are 0.098, 0.183, 0.227 and 1.967 μ M for p110 β , p110 α , p110 δ and p110 γ respectively) that displays higher potency than LY 294002 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride). Can be immobilized onto a solid phase.

storage

Store at +4°C

PI 828 Preparation Products And Raw materials

Raw materials

Preparation Products

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PI 828 Suppliers

China 24 United Kingdom 1 United States 10 USA 1 Global 36
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8449
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 15618227136
Fax
21-5161 9052
Email
info@SuperLan-chem.com
Country
China
ProdList
9748
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12308
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9730
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11289
Advantage
58
Suzhou Chenrui Biotechnology Co. LTD
Tel
17625585511
Fax
qq：1580084073
Email
1580084073@qq.com
Country
China
ProdList
462
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8141
Advantage
58

942289-87-4, PI 828Related Search:

Phenyl carbamate 2-(Dimethylamino)-8-phenyl-4H-1-benzopyran-4-one LY 294002 HYDROCHLORIDE PI 828 4H-1-Benzopyran-4-one, 2-(diethylamino)- 2-(Diethylamino)-8-phenyl-4H-1-benzopyran-4-one 2-(Etilmetilammino)-8-fenilcromone [Italian]

  • PI 828
  • 2-(4-Morpholinyl)-8-(4-aminopheny)l-4H-1-benzopyran-4-one
  • 8-(4-Aminophenyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one
  • LY 294002, 4′-NH2
  • 8-(4-aminophenyl)-2-morpholin-4-ylchromen-4-one
  • LY 294002, 4-NH - CAS 942289-87-4 - Calbiochem
  • PI 828,PI828
  • 4H-1-Benzopyran-4-one, 8-(4-aminophenyl)-2-(4-morpholinyl)-
  • 942289-87-4