2-AMINO-6-BROMOPYRIDIN-3-OL
- Product Name
- 2-AMINO-6-BROMOPYRIDIN-3-OL
- CAS No.
- 934758-27-7
- Chemical Name
- 2-AMINO-6-BROMOPYRIDIN-3-OL
- Synonyms
- 2-Amino-6-bromo-3-pyridinol;2-AMINO-6-BROMOPYRIDIN-3-OL;3-Pyridinol, 2-amino-6-bromo-;2-Amino-6-bromo-3-hydroxypyridine;2-AMINO-6-BROMOPYRIDIN-3-OL ISO 9001：2015 REACH
- CBNumber
- CB52456048
- Molecular Formula
- C5H5BrN2O
- Formula Weight
- 189.01
- MOL File
- 934758-27-7.mol
2-AMINO-6-BROMOPYRIDIN-3-OL Property
- Boiling point:
- 421.3±45.0 °C(Predicted)
- Density
- 1.898
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 4.59±0.23(Predicted)
- Appearance
- Off-white to light brown Solid
- InChI
- InChI=1S/C5H5BrN2O/c6-4-2-1-3(9)5(7)8-4/h1-2,9H,(H2,7,8)
- InChIKey
- JSRWVRYNUHTJOL-UHFFFAOYSA-N
- SMILES
- C1(N)=NC(Br)=CC=C1O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- A595815
- Product name
- 2-amino-6-bromopyridin-3-ol
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- A595815
- Product name
- 2-amino-6-bromopyridin-3-ol
- Packaging
- 100mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- FA143720
- Product name
- 2-Amino-6-bromopyridin-3-ol
- Packaging
- 250mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- Y3199
- Product name
- 2-Amino-6-bromo-3-pyridinol
- Packaging
- 250mg
- Price
- $118
- Updated
- 2021/12/16
- Product number
- FA143720
- Product name
- 2-Amino-6-bromopyridin-3-ol
- Packaging
- 500mg
- Price
- $120
- Updated
- 2021/12/16
2-AMINO-6-BROMOPYRIDIN-3-OL Chemical Properties,Usage,Production
Synthesis
443956-08-9
934758-27-7
General procedure for the synthesis of 2-amino-6-bromopyridin-3-ol from 6-bromo-2-nitropyridin-3-ol: 6-bromo-2-nitropyridin-3-ol (3 g, 13.7 mmol), iron powder (7657.88 mg, 136.99 mmol) and ammonium chloride (7329.1 mg, 136.99 mmol) were reacted with stirring at 75°C for 2 hours in a mixture of ethanol (100 mL) and water (100 mL) in a solvent mixture of ethanol (100 mL) and water, and the reaction was stirred at 75 °C for 2 h. The reaction mixture turned into a black suspension. After completion of the reaction, the mixture was cooled to room temperature and filtered through diatomaceous earth to remove insoluble impurities. The filtrate was concentrated under reduced pressure to afford the crude product 2-amino-6-bromopyridin-3-ol (2.5 g, 13.22 mmol, 96.55% yield) as a solid. The structure of the product was confirmed by 1H NMR (DMSO-d6, 400 MHz): δH= 9.71 (s, 1H), 6.74 (d, 1H), 6.50 (d, 1H), 5.92 (br s, 2H).
References
[1] Patent: WO2018/148745, 2018, A1. Location in patent: Page/Page column 163
[2] Patent: CN107188900, 2017, A. Location in patent: Paragraph 0039; 0042; 0043
[3] European Journal of Medicinal Chemistry, 2018, vol. 159, p. 255 - 266
[4] Patent: WO2018/93569, 2018, A1. Location in patent: Page/Page column 198; 199
[5] Journal of Medicinal Chemistry, 2010, vol. 53, # 3, p. 1222 - 1237
2-AMINO-6-BROMOPYRIDIN-3-OL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-AMINO-6-BROMOPYRIDIN-3-OL manufacturers
- Product
- 2-AMINO-6-BROMOPYRIDIN-3-OL 934758-27-7
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-09-28
- Product
- 2-AMINO-6-BROMOPYRIDIN-3-OL 934758-27-7
- Price
- US $500.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2018-08-04