6-BROMO-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
- Product Name
- 6-BROMO-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
- CAS No.
- 337463-88-4
- Chemical Name
- 6-BROMO-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
- Synonyms
- 6-Bromo-4H-pyrido[3,2-b][1,4]oxazin-3-one;6-BROMO-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE;2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 6-bromo-;6-broMo-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one
- CBNumber
- CB22455909
- Molecular Formula
- C7H5BrN2O2
- Formula Weight
- 229.03
- MOL File
- 337463-88-4.mol
6-BROMO-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE Property
- Boiling point:
- 423.1±45.0 °C(Predicted)
- Density
- 1.772±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 10.18±0.20(Predicted)
- Appearance
- White to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- B293340
- Product name
- 6-Bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CS-0039106
- Product name
- 6-Bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
- Purity
- 97.33%
- Packaging
- 100mg
- Price
- $62
- Updated
- 2021/12/16
- Product number
- FB144104
- Product name
- 6-Bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
- Packaging
- 250mg
- Price
- $85
- Updated
- 2021/12/16
- Product number
- CS-0039106
- Product name
- 6-Bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
- Purity
- 97.33%
- Packaging
- 250mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- Y3278
- Product name
- 6-Bromo-2H-pyridooxazin-3(4H)-one
- Packaging
- 100mg
- Price
- $142
- Updated
- 2021/12/16
6-BROMO-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE Chemical Properties,Usage,Production
Synthesis
443956-09-0
337463-88-4
Compound 3.1 (2.7 g, 8.85 mmol) was used as raw material and mixed with iron powder (2.48 g, 44.3 mmol) in acetic acid (40 mL). The reaction mixture was stirred at 100 °C for 2 hours. After the reaction was completed, it was cooled to room temperature and the reaction solution was filtered through diatomaceous earth. Water (100 mL) was added to the filtrate and extracted with dichloromethane (20 mL x 3). The organic phases were combined, dried over anhydrous sodium sulfate and concentrated. The residue was purified by silica gel column chromatography (petroleum ether/ethyl acetate= 3/1) to afford the target product, 6-bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one (Compound 3.2, 1.9 g, Yield: 95%) as a pale yellow liquid.
References
[1] Patent: CN108623615, 2018, A. Location in patent: Paragraph 0362; 0363; 0366
[2] Tetrahedron Letters, 2010, vol. 51, # 38, p. 5035 - 5037
[3] Synthetic Communications, 2013, vol. 43, # 24, p. 3315 - 3321
[4] Patent: EP2341052, 2011, A1. Location in patent: Page/Page column 35-36
[5] Patent: WO2017/199265, 2017, A1. Location in patent: Paragraph 000134
6-BROMO-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-BROMO-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE manufacturers
- Product
- 6-broMo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one 337463-88-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 0.0001kg
- Purity
- 98%min
- Supply Ability
- 100kgs/month
- Release date
- 2022-05-09
- Product
- 6-BROMO-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE 337463-88-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-08