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Methyl 6-broMo-3-Methoxypicolinate

Product Name
Methyl 6-broMo-3-Methoxypicolinate
CAS No.
945954-94-9
Chemical Name
Methyl 6-broMo-3-Methoxypicolinate
Synonyms
Methyl 6-broMo-3-Methoxypicolinate;methyl 6-bromo-3-methoxypyridine-2-carboxylate;methyl 6-bromo-3-methoxypyridine-2-carboxylate - [AC80521];2-Pyridinecarboxylic acid, 6-bromo-3-methoxy-, methyl ester
CBNumber
CB62549552
Molecular Formula
C8H8BrNO3
Formula Weight
246.06
MOL File
945954-94-9.mol
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Methyl 6-broMo-3-Methoxypicolinate Property

Boiling point:
338.2±37.0 °C(Predicted)
Density 
1.530±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
-1.56±0.10(Predicted)
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Matrix Scientific
Product number
143724
Product name
Methyl 6-bromo-3-methoxypicolinate
Packaging
250.00mg
Price
$39
Updated
2026/05/18
Matrix Scientific
Product number
143724
Product name
Methyl 6-bromo-3-methoxypicolinate
Packaging
1.00g
Price
$109
Updated
2026/05/18
Matrix Scientific
Product number
143724
Product name
Methyl 6-bromo-3-methoxypicolinate
Packaging
5.00g
Price
$367
Updated
2026/05/18
Synthonix
Product number
AC80521
Product name
methyl 6-bromo-3-methoxypyridine-2-carboxylate
Purity
96%
Packaging
250mg
Price
$51.71
Updated
2026/05/06
Synthonix
Product number
AC80521
Product name
methyl 6-bromo-3-methoxypyridine-2-carboxylate
Purity
96%
Packaging
500mg
Price
$79.56
Updated
2026/05/06
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Methyl 6-broMo-3-Methoxypicolinate Chemical Properties,Usage,Production

Synthesis

321601-48-3

74-88-4

945954-94-9

General procedure for the synthesis of methyl 6-bromo-3-methoxypyridine carboxylate from methyl 6-bromo-3-hydroxypyridine-2-carboxylate and iodomethane: Methyl 6-bromo-3-hydroxypyridine-2-carboxylate (4 g, 17.2 mmol), iodomethane (7.15 g, 34.5 mmol) and potassium carbonate (4.76 g, 34.5 mmol) were dissolved in N,N- dimethylformamide (50 mL) and the reaction was stirred at room temperature for 3 hours. After completion of the reaction, the reaction mixture was concentrated under reduced pressure, diluted with water and extracted with ethyl acetate (50 mL x 3). The organic layers were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product methyl 6-bromo-3-methoxypyridinecarboxylate (4 g, yield: 90%). The product was identified by NMR hydrogen spectroscopy (CDCl3, 400 MHz): δ 7.56 (d, J = 8.0 Hz, 1H), 7.25 (d, J = 8.0 Hz, 1H), 3.94 (s, 3H), 3.90 (s, 3H). Mass spectrum (M + H)+: 256/258.

References

[1] Patent: WO2014/121418, 2014, A1. Location in patent: Page/Page column 45
[2] Patent: EP3255042, 2017, A2. Location in patent: Paragraph 0180; 0183
[3] Patent: WO2007/89031, 2007, A1. Location in patent: Page/Page column 84-85
[4] Patent: WO2014/209727, 2014, A1. Location in patent: Page/Page column 39
[5] Patent: WO2014/205593, 2014, A1. Location in patent: Page/Page column 41; 42

Methyl 6-broMo-3-Methoxypicolinate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 6-broMo-3-Methoxypicolinate Suppliers

JinYan Chemicals(ShangHai) Co.,Ltd.
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