ChemicalBook > CAS DataBase List > THIOPERAMIDE MALEATE

THIOPERAMIDE MALEATE

Product Name
THIOPERAMIDE MALEATE
CAS No.
106243-16-7
Chemical Name
THIOPERAMIDE MALEATE
Synonyms
Thiop;MR 12842;thioperamide;THIOPERAMIDE MALEATE;THIOPERAMIDE MALEATE SALT;THIOPERAMIDE MALEATE (MR 12842) POTENT A ND SELECTIVE;N-Cyclohexyl-4-(imidazol-4-yl)-1-piperidinecarbothioamide;N-Cyclohexyl-4-(1H-imidazol-4-yl)-1-piperidinecarbothioamide;N-CYCLOHEXYL-4-(1H-IMIDAZOL-5-YL)-1-PIPERIDINECARBOTHIOAMIDE;N-Cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide
CBNumber
CB5245732
Molecular Formula
C15H24N4S
Formula Weight
292.44
MOL File
106243-16-7.mol
More
Less

THIOPERAMIDE MALEATE Property

storage temp. 
Store at -20°C
solubility 
H2O: 10 mg/mL
form 
solid
color 
white
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Tocris
Product number
0644
Product name
Thioperamide
Purity
≥99%(HPLC)
Packaging
10
Price
$123
Updated
2021/12/16
Tocris
Product number
0644
Product name
Thioperamide
Purity
≥99%(HPLC)
Packaging
50
Price
$515
Updated
2021/12/16
TRC
Product number
T344808
Product name
Thioperamide
Packaging
10mg
Price
$110
Updated
2021/12/16
Usbiological
Product number
256923
Product name
Thioperamide
Packaging
10mg
Price
$389
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007635
Product name
THIOPERAMIDE
Purity
95.00%
Packaging
100MG
Price
$2116.25
Updated
2021/12/16
More
Less

THIOPERAMIDE MALEATE Chemical Properties,Usage,Production

Uses

Thioperamide is a highly potent and selective ligand for histamine H3-receptors.

Definition

ChEBI: Thioperamide is a primary aliphatic amine.

Biological Activity

Potent histamine H 3 and H 4 antagonist/inverse agonist. K i values are 25 and 27 nM for human recombinant H 3 and H 4 receptors respectively. Blocks eosinophil shape change (IC 50 = 1.4 μ M) and chemotaxis (IC 50 = 519 nM) induced by histamine. Freely crosses the blood-brain barrier. Also available as part of the Histamine H 3 Receptor Tocriset™ .

in vivo

Thioperamide (5-20 mg/kg; i.p.) is able to facilitate reconsolidation of a contextually-conditioned fear memory in C57BL/6J mice[3].

Animal Model:Naive female C57BL/6J mice[3]
Dosage:5, 10 or 20 mg/kg
Administration:Injections (i.p.)
Result:Facilitated reconsolidation of a contextually-conditioned fear memory.

IC 50

H3 Receptor

storage

Store at -20°C

THIOPERAMIDE MALEATE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

THIOPERAMIDE MALEATE Suppliers

China 19 Europe 1 Germany 2 Japan 1 Switzerland 1 United Kingdom 6 United States 9 USA 1 Global 40
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
Beijin Yangguang Furui Chemical co.,Ltd.
Tel
010-57495520 13521095525
Email
zhw512@foxmail.com
Country
China
ProdList
488
Advantage
55
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9125
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
Shanghai Universal Biotech Co.,Ltd
Tel
15921930842 15921930842
Email
yh-wang@univ-bio.com
Country
China
ProdList
25004
Advantage
58
QUALITY CONTROL SOLUTIONS LTD.
Tel
+86-0755-66853366 +86-13670046396
Email
export03@qcsrm.com
Country
China
ProdList
24342
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Nantong QuanYi Biotechnology Co., Ltd
Tel
0513-66337626 18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
5929
Advantage
58
Shanghai Fine Biotech Co.，Ltd
Tel
18221172427
Email
sale@fine-biotech.com
Country
China
ProdList
2746
Advantage
58
R&D Systems, Inc
Tel
18003437475
Fax
1-612-656-4400
Email
rdname@qq.com
Country
China
ProdList
6960
Advantage
58
Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
Advantage
58
Guangzhou Ruifeng Biotechnology Co., Ltd.
Tel
14715141318
Country
CHINA
ProdList
181
Advantage
58
Foshan Minghua Biotechnology Co., Ltd.
Tel
18312287787
Country
CHINA
ProdList
196
Advantage
58
Neobioscience Co., Ltd.
Tel
--
Fax
--
Email
info@neobioscience.com
Country
CHINA
ProdList
6207
Advantage
58
Absin Bioscience Inc.
Tel
--
Fax
--
Email
chenjw@absin.cn
Country
CHINA
ProdList
6208
Advantage
58
Advanced Technology & Industrial Co., Ltd.
Tel
--
Fax
--
Email
sales@advtechind.com
Country
China
ProdList
6523
Advantage
75

106243-16-7, THIOPERAMIDE MALEATERelated Search:

1,3-Dibutyl-2-thiourea 1-CYCLOHEXYL-2-THIOUREA 4-(1H-IMIDAZOL-4-YL)-1-METHYL-PIPERIDINE 4-(1H-IMIDAZOLE-4(5)-YL) PIPERIDINE N,N-DIETHYLTHIOUREA 1-PIPERIDINETHIOCARBOXAMIDE THIOPERAMIDE MALEATE N,N'-DI-N-PROPYLTHIOUREA

  • N-CYCLOHEXYL-4-(1H-IMIDAZOL-4-YL)-1-PIPERIDINECARBOTHIOAMIDE MALEATE
  • MR 12842
  • THIOPERAMIDE MALEATE
  • THIOPERAMIDE MALEATE SALT
  • THIOPERAMIDE MALEATE (MR 12842) POTENT A ND SELECTIVE
  • N-Cyclohexyl-4-(1H-imidazol-4-yl)-1-piperidinecarbothioamide
  • Thiop
  • N-Cyclohexyl-4-(imidazol-4-yl)-1-piperidinecarbothioamide
  • thioperamide
  • N-CYCLOHEXYL-4-(IMIDAZOL-4-YL)-1-PIPERIDINECARBOTHIOAMIDE MALEATE
  • N-CYCLOHEXYL-4-(1H-IMIDAZOL-5-YL)-1-PIPERIDINECARBOTHIOAMIDE
  • N-Cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide
  • 1-Piperidinecarbothioamide, N-cyclohexyl-4-(1H-imidazol-5-yl)-
  • 106243-16-7
  • C15H24N4SC4H4O4
  • Potent and selective H3 histamine receptor antagonist that crosses the blood-brain barrier.
  • Histamine receptor
  • Histamine