(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE
- Product Name
- (6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE
- CAS No.
- 151792-53-9
- Chemical Name
- (6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE
- Synonyms
- (6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE;(1R,4S)-2-Boc-3-oxo-2-azabicyclo[2.2.1]hept-5-ene;(1R,4S)-(-)-2-tert-Butoxycarbonyl-2-azabicyclo[2.2.1]hept-5-en-3-one;tert-butyl (1R,4S)-3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate;(1R,4S)-tert-butyl 3-oxo-2-aza-bicyclo[2.2.1]hept-5-ene-2-carboxylate;racemic-(1R,4S)-tert-butyl 3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate*;2-Methyl-2-Propanyl (1R,4S)-3-Oxo-2-Azabicyclo[2.2.1]Hept-5-Ene-2-Carboxylate;2-Azabicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-oxo-,1,1-diMethylethyl ester, (1R,4S)-;(1R,?4S)?-3-?Oxo-2-?azabicyclo[2.2.1]?hept-?5-?ene-?2-?carboxylic acid 1,?1-?Dimethylethyl Ester
- CBNumber
- CB52459670
- Molecular Formula
- C11H15NO3
- Formula Weight
- 209.24
- MOL File
- 151792-53-9.mol
(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE Property
- Melting point:
- 85.0-86.5 °C
- Boiling point:
- 339.8±31.0 °C(Predicted)
- Density
- 1?+-.0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- -2.32±0.20(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- O848430
- Product name
- (1R,4S)-3-Oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylicacid1,1-DimethylethylEster
- Packaging
- 10g
- Price
- $870
- Updated
- 2021/12/16
- Product number
- CCH0032302
- Product name
- (1R,4S)-TERT-BUTYL-3-OXO-2-AZABICYCLO-[2.2.1]-HEPT-5-ENE-2-CARBOXYLATE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $975.45
- Updated
- 2021/12/16
- Product number
- CS-M2481
- Product name
- (1R,4S)-tert-Butyl3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate
- Purity
- 99.95%
- Packaging
- 5g
- Price
- $450
- Updated
- 2021/12/16
- Product number
- CS-M2481
- Product name
- (1R,4S)-tert-Butyl3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate
- Purity
- 99.95%
- Packaging
- 100mg
- Price
- $74
- Updated
- 2021/12/16
- Product number
- CS-M2481
- Product name
- (1R,4S)-tert-Butyl3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate
- Purity
- 99.95%
- Packaging
- 250mg
- Price
- $90
- Updated
- 2021/12/16
(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE Chemical Properties,Usage,Production
Uses
(1R,?4S)?-3-?Oxo-2-?azabicyclo[2.2.1]?hept-?5-?ene-?2-?carboxylic acid 1,?1-?Dimethylethyl Ester is an intermediate in synthesizing ent-Abacavir (Abacavir EP Impurity A) (A105015), an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE manufacturers
- Product
- (6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE 151792-53-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-20