ChemicalBook > CAS DataBase List > (6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE

(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE

Product Name
(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE
CAS No.
151792-53-9
Chemical Name
(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE
Synonyms
(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE;(1R,4S)-2-Boc-3-oxo-2-azabicyclo[2.2.1]hept-5-ene;(1R,4S)-(-)-2-tert-Butoxycarbonyl-2-azabicyclo[2.2.1]hept-5-en-3-one;tert-butyl (1R,4S)-3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate;(1R,4S)-tert-butyl 3-oxo-2-aza-bicyclo[2.2.1]hept-5-ene-2-carboxylate;racemic-(1R,4S)-tert-butyl 3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate*;2-Methyl-2-Propanyl (1R,4S)-3-Oxo-2-Azabicyclo[2.2.1]Hept-5-Ene-2-Carboxylate;2-Azabicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-oxo-,1,1-diMethylethyl ester, (1R,4S)-;(1R,?4S)?-3-?Oxo-2-?azabicyclo[2.2.1]?hept-?5-?ene-?2-?carboxylic acid 1,?1-?Dimethylethyl Ester
CBNumber
CB52459670
Molecular Formula
C11H15NO3
Formula Weight
209.24
MOL File
151792-53-9.mol
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(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE Property

Melting point:
85.0-86.5 °C
Boiling point:
339.8±31.0 °C(Predicted)
Density 
1?+-.0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
-2.32±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
O848430
Product name
(1R,​4S)​-3-​Oxo-2-​azabicyclo[2.2.1]​hept-​5-​ene-​2-​carboxylicacid1,​1-​DimethylethylEster
Packaging
10g
Price
$870
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0032302
Product name
(1R,4S)-TERT-BUTYL-3-OXO-2-AZABICYCLO-[2.2.1]-HEPT-5-ENE-2-CARBOXYLATE
Purity
95.00%
Packaging
1G
Price
$975.45
Updated
2021/12/16
ChemScene
Product number
CS-M2481
Product name
(1R,4S)-tert-Butyl3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate
Purity
99.95%
Packaging
5g
Price
$450
Updated
2021/12/16
ChemScene
Product number
CS-M2481
Product name
(1R,4S)-tert-Butyl3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate
Purity
99.95%
Packaging
100mg
Price
$74
Updated
2021/12/16
ChemScene
Product number
CS-M2481
Product name
(1R,4S)-tert-Butyl3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate
Purity
99.95%
Packaging
250mg
Price
$90
Updated
2021/12/16
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(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE Chemical Properties,Usage,Production

Uses

(1R,?4S)?-3-?Oxo-2-?azabicyclo[2.2.1]?hept-?5-?ene-?2-?carboxylic acid 1,?1-?Dimethylethyl Ester is an intermediate in synthesizing ent-Abacavir (Abacavir EP Impurity A) (A105015), an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE Suppliers

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View Lastest Price from (6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE manufacturers

Career Henan Chemical Co
Product
(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE 151792-53-9
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2019-12-20

151792-53-9, (6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONERelated Search:

tert-butyl (3aS,6aR)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,3a,4,6a-tetrahydrocyclopenta[c]pyrrole-2(1H)-carboxylate 3-N-Boc-Cis-Tetrahydrofuran-3,4-Diamine tert-butyl (3aR,5s,6aS)-5-(hydroxymethyl)hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate exo-3-Boc-3-azabicyclo[3.1.0]hexane-6-methanol Carbamic acid, [(3S,4S)-4-aminotetrahydro-3-furanyl]-, 1,1-dimethylethyl ester tert-butyl ((3S,4S)-4-aminotetrahydrofuran-3-yl)carbamate rel tert-butyl ((3R,4R)-4-hydroxytetrahydro-2H-pyran-3-yl)carbamate tert-Butyl 5-(hydroxymethyl)hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate rel-(3r,4r)-3-(boc-amino)-5-fluoropiperidine (2S,4R)-4-hydroxy-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester tert-butyl ((3R,4R)-4-aminotetrahydrofuran-3-yl)carbamate N-BOC-(3S,4S)-3,4-PYRROLIDINEDIOL tert-butyl (3S)-3-(hydroxymethyl)-2-azabicyclo[3.1.0]hexane-2-carboxylate tert-butyl (3R,4S)-3-amino-4-methylpyrrolidine-1-carboxylate tert-butyl (3R)-3-aMino-4-(hydroxyMethyl)pyrrolidine-1-carboxyla (R)-1-BOC-3-(Hydroxymethyl)piperazine tert-butyl (3aR,7aS)-6-oxohexahydropyrano[3,4-c]pyrrole-2(3H)-carboxylate tert-butyl (3aR,5s,6aS)-5-cyanohexahydrocyclopenta[c]-pyrrole-2(1H)-carboxylate

  • (6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE
  • (1R,4S)-tert-butyl 3-oxo-2-aza-bicyclo[2.2.1]hept-5-ene-2-carboxylate
  • 2-Azabicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-oxo-,1,1-diMethylethyl ester, (1R,4S)-
  • tert-butyl (1R,4S)-3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate
  • racemic-(1R,4S)-tert-butyl 3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate*
  • (1R,?4S)?-3-?Oxo-2-?azabicyclo[2.2.1]?hept-?5-?ene-?2-?carboxylic acid 1,?1-?Dimethylethyl Ester
  • (1R,4S)-(-)-2-tert-Butoxycarbonyl-2-azabicyclo[2.2.1]hept-5-en-3-one
  • 2-Methyl-2-Propanyl (1R,4S)-3-Oxo-2-Azabicyclo[2.2.1]Hept-5-Ene-2-Carboxylate
  • (1R,4S)-2-Boc-3-oxo-2-azabicyclo[2.2.1]hept-5-ene
  • 151792-53-9