2,4,8-TRICHLOROQUINAZOLINE
- Product Name
- 2,4,8-TRICHLOROQUINAZOLINE
- CAS No.
- 62484-29-1
- Chemical Name
- 2,4,8-TRICHLOROQUINAZOLINE
- Synonyms
- 2,4,8-TRICHLOROQUINAZOLINE;Quinazoline, 2,4,8-trichloro-
- CBNumber
- CB52464517
- Molecular Formula
- C8H3Cl3N2
- Formula Weight
- 233.48
- MOL File
- 62484-29-1.mol
2,4,8-TRICHLOROQUINAZOLINE Property
- Boiling point:
- 309.1±24.0 °C(Predicted)
- Density
- 1.60
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -1.68±0.30(Predicted)
- Appearance
- White to yellow Solid
Safety
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 3H32-5-WJ
- Product name
- 2,4,8-Trichloroquinazoline
- Purity
- 97%
- Packaging
- 250mg
- Price
- $116
- Updated
- 2021/12/16
- Product number
- Z4958
- Product name
- 2,4,8-Trichloroquinazoline
- Packaging
- 250mg
- Price
- $131
- Updated
- 2021/12/16
- Product number
- OR926964
- Product name
- 2,4,8-Trichloroquinazoline
- Purity
- 97%
- Packaging
- 1g
- Price
- $171
- Updated
- 2021/12/16
- Product number
- Z4958
- Product name
- 2,4,8-Trichloroquinazoline
- Packaging
- 1g
- Price
- $253
- Updated
- 2021/12/16
- Product number
- 3H32-5-WJ
- Product name
- 2,4,8-Trichloroquinazoline
- Purity
- 97%
- Packaging
- 1g
- Price
- $274
- Updated
- 2021/12/16
2,4,8-TRICHLOROQUINAZOLINE Chemical Properties,Usage,Production
Synthesis
62484-22-4
62484-29-1
General procedure for the synthesis of 2,4,8-trichloroquinazoline from 8-chloroquinazoline-2,4(1H,3H)-dione: (1041) To 8-chloroquinazoline-2,4(1H,3H)-dione (3.8 g, 19.33 mmol) was added 60 mL of phosphorus oxychloride (POCl3). The reaction mixture was heated to reflux for 16 hours. Upon completion of the reaction, the excess phosphorous trichloride was evaporated under reduced pressure and the residue was purified by column chromatography to afford 2,4,8-trichloroquinazoline (3.11 g, 76% yield). Mass spectrum (ESI+): m/z = 233 [M + 1].
References
[1] Patent: US2016/168140, 2016, A1. Location in patent: Paragraph 1041
[2] Journal of Medicinal Chemistry, 2007, vol. 50, # 10, p. 2297 - 2300
[3] Patent: US5688803, 1997, A
[4] Patent: EP2226315, 2010, A1. Location in patent: Page/Page column 33
[5] Journal of Medicinal Chemistry, 2014, vol. 57, # 12, p. 5141 - 5156
2,4,8-TRICHLOROQUINAZOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
2,4,8-TRICHLOROQUINAZOLINE Suppliers
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- 8485655694
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View Lastest Price from 2,4,8-TRICHLOROQUINAZOLINE manufacturers
- Product
- 2,4,8-TRICHLOROQUINAZOLINE 62484-29-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-01-12