ChemicalBook > CAS DataBase List > 2-Bromo-5-trifluoromethoxypyridine
2-Bromo-5-trifluoromethoxypyridine
- Product Name
- 2-Bromo-5-trifluoromethoxypyridine
- CAS No.
- 888327-36-4
- Chemical Name
- 2-Bromo-5-trifluoromethoxypyridine
- Synonyms
- Lasmiditan Impurity 41;2-Bromo-5-(trifluoromethoxy);2-Bromo-5-trifluoromethoxypyridine;Pyridine,2-bromo-5-(trifluoromethoxy)-
- CBNumber
- CB52470062
- Molecular Formula
- C6H3BrF3NO
- Formula Weight
- 241.99
- MOL File
- 888327-36-4.mol
More
Less
2-Bromo-5-trifluoromethoxypyridine Property
- Boiling point:
- 63-66 °C(Press: 11 Torr)
- Density
- 1.737±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -3.55±0.10(Predicted)
- form
- liquid
- color
- Clear, almost colourless
- InChI
- InChI=1S/C6H3BrF3NO/c7-5-2-1-4(3-11-5)12-6(8,9)10/h1-3H
- InChIKey
- RKXYQQVLVNEAFB-UHFFFAOYSA-N
- SMILES
- C1(Br)=NC=C(OC(F)(F)F)C=C1
More
Less
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H317May cause an allergic skin reaction
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- MNO000171
- Product name
- 2-Bromo-5-(trifluoromethoxy)pyridine
- Packaging
- 1g
- Price
- $356
- Updated
- 2025/07/31
American Custom Chemicals Corporation
- Product number
- HCH0363275
- Product name
- 2-BROMO-5-(TRIFLUOROMETHOXY)PYRIDINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.54
- Updated
- 2021/12/16
Apolloscientific
- Product number
- PC421021
- Product name
- 2-Bromo-5-(trifluoromethoxy)pyridine
- Packaging
- 5g
- Price
- $548
- Updated
- 2021/12/16
SynQuest Laboratories
- Product number
- 4H07-9-41
- Product name
- 2-Bromo-5-(trifluoromethoxy)pyridine
- Packaging
- 5G
- Price
- $877
- Updated
- 2021/12/16
Apolloscientific
- Product number
- PC421021
- Product name
- 2-Bromo-5-(trifluoromethoxy)pyridine
- Packaging
- 500mg
- Price
- $92
- Updated
- 2021/12/16
More
Less
2-Bromo-5-trifluoromethoxypyridine Chemical Properties,Usage,Production
Synthesis
1206972-45-3
888327-36-4
General procedure for the synthesis of 2-bromo-5-trifluoromethoxypyridine: 2-chloro-5-(trifluoromethoxy)pyridine (6, 7.0 g, 35.4 mmol) and bromotrimethylsilane (10.8 g, 9.3 mL, 70.8 mmol, 2 eq.) were dissolved in propionitrile (35 mL) and heated to reflux for 24 hours. The reaction process was monitored by gas chromatography (GC) to confirm 100% conversion. Upon completion of the reaction, the mixture was vacuum distilled to afford pure 2-bromo-5-trifluoromethoxypyridine (31, 7.0 g, 28.7 mmol, 81% yield) as a colorless oil. Boiling point: 63-66°C (14 mbar). NMR data: 1H NMR (CDCl3, 300 MHz): δ= 8.34 (d, J = 2.8 Hz, 1H), 7.56 (d, J = 8.7 Hz, 1H), 7.45 (dd, J = 8.7, 2.8 Hz, 1H). 19F NMR (CDCl3, 282 MHz): δ= -58.8. 13C NMR (CDCl3, 75 MHz): δ= 145.6, 143.1, 139.2, 131.4, 129.0, 120.1 (q, J = 260 Hz). Elemental analysis: C6H3BrF3NO (molecular weight 241) Calculated value (%): C 29.78, H 1.25, N 5.79; measured value: C 29.96, H 1.41, N 5.64.
References
[1] Patent: WO2010/40461, 2010, A1. Location in patent: Page/Page column 38-39
[2] European Journal of Organic Chemistry, 2010, # 31, p. 6043 - 6066
2-Bromo-5-trifluoromethoxypyridine Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
2-Bromo-5-trifluoromethoxypyridine Suppliers
- Tel
- 029-86115547 17791676824
- Fax
- 02151602123
- sales@cochemical.com
- Country
- China
- ProdList
- 3014
- Advantage
- 58
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 0519-81096292 15312577869
- chemscaler@yahoo.com.cn
- Country
- China
- ProdList
- 311
- Advantage
- 60
- Tel
- 0411-62313318 13942603642
- Fax
- 0411-87549748
- info@allychem.com
- Country
- China
- ProdList
- 1028
- Advantage
- 65
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- sales@ahpharmatech.com
- Country
- China
- ProdList
- 5734
- Advantage
- 55
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- 15332490153
- Fax
- QQ 2725398181
- newprochem@126.com
- Country
- China
- ProdList
- 991
- Advantage
- 55
- Tel
- 010-60400365-8001 15910885229
- Fax
- 010-60400361
- service@bellenchem.com
- Country
- China
- ProdList
- 4514
- Advantage
- 60
- Tel
- 18055517827
- sales@agilebiochem.com
- Country
- China
- ProdList
- 1003
- Advantage
- 50
- Tel
- 0519-85528066 13775048983
- Fax
- 0519-85528066
- sales@hopschem.com
- Country
- China
- ProdList
- 31553
- Advantage
- 55
- Tel
- 15902830537
- zhanghao@happysyn.com
- Country
- China
- ProdList
- 3180
- Advantage
- 55
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 15374522761
- Fax
- QQ:2853117752
- 3003392093@yongstandards.com
- Country
- China
- ProdList
- 10000
- Advantage
- 55
- Tel
- 17836913271
- Fax
- 0374-8348899
- 3224305243@qq.com
- Country
- China
- ProdList
- 2952
- Advantage
- 58
- Tel
- 86-0573-85866609 13325730825
- Fax
- 0573-85866609
- 945717149@qq.com
- Country
- China
- ProdList
- 8595
- Advantage
- 58
- Tel
- 025-66113011 13155353615
- Fax
- (7)02557626880
- qzhang@aikonchem.com
- Country
- China
- ProdList
- 15394
- Advantage
- 58
- Tel
- 15088289376
- 248775804@qq.com
- Country
- China
- ProdList
- 4995
- Advantage
- 58
- Tel
- 4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52687
- Advantage
- 58
- Tel
- 18916696128
- service@snowpharm.com
- Country
- China
- ProdList
- 1369
- Advantage
- 58
- Tel
- 028-84641798 18782128315
- 3302391190@qq.com
- Country
- China
- ProdList
- 9800
- Advantage
- 55
- Tel
- +86-0551-65418684 +8618949823763
- Fax
- 0086-551-65418684
- sales@tnjchem.com
- Country
- China
- ProdList
- 25356
- Advantage
- 58
- Tel
- +86-27-50766799 +8618062016861
- contact@labnetwork.com
- Country
- China
- ProdList
- 19987
- Advantage
- 58
- Tel
- +86-0571-88938639 +8617705817739
- Fax
- +86-571-88938652，+86-571- 88492614
- info@dycnchem.com
- Country
- China
- ProdList
- 52846
- Advantage
- 58
- Tel
- +86-0731-85567275 13298656710
- Fax
- QQ:3554193828
- sales05@chemfish.com
- Country
- China
- ProdList
- 7448
- Advantage
- 58
- Tel
- 13981836672
- 2560370848@qq.com
- Country
- China
- ProdList
- 2807
- Advantage
- 58
- Tel
- 021-021-54321516 17717324060
- 2719672468@qq.com
- Country
- China
- ProdList
- 2032
- Advantage
- 58
- Tel
- 15990591583
- Fax
- qq: 1050376806 mailbox : sales@nbpharmabridge.com
- Country
- China
- ProdList
- 6108
- Advantage
- 58
- Tel
- 021-50795510 4000665055
- sales@accelachem.com
- Country
- China
- ProdList
- 10467
- Advantage
- 58
- Tel
- +86-13759708231
- asherw9@hotmail.com
- Country
- China
- ProdList
- 2373
- Advantage
- 58
- Tel
- 021-58461859 15821823057
- service@aiviche.com
- Country
- China
- ProdList
- 49312
- Advantage
- 58
- Tel
- +86-0371-86658258 +8613203830695
- Fax
- 0086-371-86658258
- factory@coreychem.com
- Country
- China
- ProdList
- 29798
- Advantage
- 58
- Tel
- +86-021-021-50872116 +8613122107989
- contact@fuxinpharm.com
- Country
- China
- ProdList
- 10000
- Advantage
- 58
- Tel
- +8613580539051
- joe@yuhengpharm.com
- Country
- CHINA
- ProdList
- 21142
- Advantage
- 58
- Tel
- 029-029-81024372 17792795018
- Fax
- 029-88380327
- 1027@dideu.com
- Country
- China
- ProdList
- 9997
- Advantage
- 58
- Tel
- 0371-0371-55135753 18003832934
- Fax
- QQ：2853979818
- 2853979818@qq.com
- Country
- China
- ProdList
- 9991
- Advantage
- 58
- Tel
- 021-51816796-820 13611835272
- Fax
- 021-5161 3951
- sales2@sunwaypharm.com
- Country
- China
- ProdList
- 44119
- Advantage
- 58
- Tel
- 19938173342 19181793067
- 1486288711@qq.com
- Country
- China
- ProdList
- 197
- Advantage
- 58
- Tel
- 15380789538
- 2885743537@qq.com
- Country
- China
- ProdList
- 8205
- Advantage
- 58
- Tel
- 400-8210725 4008210725
- malulu@leyan.com
- Country
- China
- ProdList
- 40000
- Advantage
- 58
- Tel
- 18992018580 18165105898
- Fax
- QQ:1617857088
- 13608210612@163.com
- Country
- China
- ProdList
- 2984
- Advantage
- 58
- Tel
- 400-6005915
- sales@picasso-e.com
- Country
- China
- ProdList
- 39653
- Advantage
- 58
- Tel
- 15553348166
- m15553348166@163.com
- Country
- China
- ProdList
- 9967
- Advantage
- 58
- Tel
- 15652467323
- sales@inno-chem.com.cn
- Country
- China
- ProdList
- 8293
- Advantage
- 58
- Tel
- 17602663561
- public@dreamchem.cn
- Country
- China
- ProdList
- 993
- Advantage
- 58
- Tel
- 13186333400
- cuichengbio@163.com
- Country
- China
- ProdList
- 4846
- Advantage
- 58
- Tel
- 13611612777
- 3627377363@qq.com
- Country
- China
- ProdList
- 4015
- Advantage
- 58
- Tel
- 17743531240
- kytd20@sina.com
- Country
- China
- ProdList
- 1514
- Advantage
- 58
- Tel
- 17791728244
- 3356623179@qq.com
- Country
- China
- ProdList
- 879
- Advantage
- 58
- Tel
- 021-57520305 13795461237
- zhuruyan@jskchem.com
- Country
- China
- ProdList
- 49234
- Advantage
- 58
More
Less
View Lastest Price from 2-Bromo-5-trifluoromethoxypyridine manufacturers
Career Henan Chemical Co
- Product
- 2-Bromo-5-trifluoromethoxypyridine 888327-36-4
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-14
888327-36-4, 2-Bromo-5-trifluoromethoxypyridineRelated Search:
4-Bromopyridine hydrochloride
Pyridinium tribromide
3-Pyridyl bromide
2-Bromopyridine
2-Chloro-5-trifluoromethylpyridine