ChemicalBook > CAS DataBase List > 1,3,5-Trihydroxy-4-prenylxanthone

1,3,5-Trihydroxy-4-prenylxanthone

Product Name
1,3,5-Trihydroxy-4-prenylxanthone
CAS No.
53377-61-0
Chemical Name
1,3,5-Trihydroxy-4-prenylxanthone
Synonyms
5-Trihydroxy-4-prenylxanthone;1,3,5-Trihydroxy-4-prenylxanthone;1,3,5-Trihydroxy-4-(3-Methylbut-2-en-1-yl)-9H-xanthen-9-one;1,3,5-Trihydroxy-4-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one;9H-Xanthen-9-one, 1,3,5-trihydroxy-4-(3-methyl-2-buten-1-yl)-;1,3,5Trihydroxy4prenylxanthone,1,3,5 Trihydroxy 4 prenylxanthone
CBNumber
CB52519192
Molecular Formula
C18H16O5
Formula Weight
312.32
MOL File
53377-61-0.mol
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1,3,5-Trihydroxy-4-prenylxanthone Property

solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
powder
color 
Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom
Product number
CFN98891
Product name
1,3,5-Trihydroxy-4-prenylxanthone
Packaging
5mg
Price
$536
Updated
2021/12/16
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1,3,5-Trihydroxy-4-prenylxanthone Chemical Properties,Usage,Production

Description

1,3,5-Trihydroxy-4-prenylxanthone is a relatively potent inhibitor of phosphodiesterase type 5 (PDE5), with an IC50 value of 3.0 μM. 1,3,5-Trihydroxy-4-prenylxanthone inhibits LPS-induced NF-κB and AP-1 activations by interfering with the posttranslational modification (phosphorylation and/or ubiquitinylation) of IRAK-1 in the cell membrane to impede TAK1-mediated activation of IKK and MAPKs signal transduction. 3. 1,3,5-Trihydroxy-4-prenylxanthone shows in vitro inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 values of 56.3plusmn;0.4 and 46.0plusmn;0.3 M, respectively.

target

NF-kB | IkB | AP-1 | JNK | ERK | TGF-β/Smad | AChR | IKK

1,3,5-Trihydroxy-4-prenylxanthone Preparation Products And Raw materials

Raw materials

Preparation Products

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1,3,5-Trihydroxy-4-prenylxanthone Suppliers

China 28 United States 4 Global 32
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View Lastest Price from 1,3,5-Trihydroxy-4-prenylxanthone manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
1,3,5-Trihydroxy-4-prenylxanthone 53377-61-0
Price
US $0.00-0.00/KG
Min. Order
5mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-06

53377-61-0, 1,3,5-Trihydroxy-4-prenylxanthoneRelated Search:

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  • 1,3,5-Trihydroxy-4-prenylxanthone
  • 1,3,5-Trihydroxy-4-(3-Methylbut-2-en-1-yl)-9H-xanthen-9-one
  • 9H-Xanthen-9-one, 1,3,5-trihydroxy-4-(3-methyl-2-buten-1-yl)-
  • 1,3,5-Trihydroxy-4-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
  • 5-Trihydroxy-4-prenylxanthone
  • 1,3,5Trihydroxy4prenylxanthone,1,3,5 Trihydroxy 4 prenylxanthone
  • 53377-61-0