ChemicalBook > CAS DataBase List > 1,3,5-Trihydroxy-4-prenylxanthone
1,3,5-Trihydroxy-4-prenylxanthone
- Product Name
- 1,3,5-Trihydroxy-4-prenylxanthone
- CAS No.
- 53377-61-0
- Chemical Name
- 1,3,5-Trihydroxy-4-prenylxanthone
- Synonyms
- 5-Trihydroxy-4-prenylxanthone;1,3,5-Trihydroxy-4-prenylxanthone;1,3,5-Trihydroxy-4-(3-Methylbut-2-en-1-yl)-9H-xanthen-9-one;1,3,5-Trihydroxy-4-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one;9H-Xanthen-9-one, 1,3,5-trihydroxy-4-(3-methyl-2-buten-1-yl)-;1,3,5Trihydroxy4prenylxanthone,1,3,5 Trihydroxy 4 prenylxanthone
- CBNumber
- CB52519192
- Molecular Formula
- C18H16O5
- Formula Weight
- 312.32
- MOL File
- 53377-61-0.mol
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1,3,5-Trihydroxy-4-prenylxanthone Property
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- powder
- color
- Yellow
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N-Bromosuccinimide Price
Arctom
- Product number
- CFN98891
- Product name
- 1,3,5-Trihydroxy-4-prenylxanthone
- Packaging
- 5mg
- Price
- $536
- Updated
- 2021/12/16
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1,3,5-Trihydroxy-4-prenylxanthone Chemical Properties,Usage,Production
Description
1,3,5-Trihydroxy-4-prenylxanthone is a relatively potent inhibitor of phosphodiesterase type 5 (PDE5), with an IC50 value of 3.0 μM. 1,3,5-Trihydroxy-4-prenylxanthone inhibits LPS-induced NF-κB and AP-1 activations by interfering with the posttranslational modification (phosphorylation and/or ubiquitinylation) of IRAK-1 in the cell membrane to impede TAK1-mediated activation of IKK and MAPKs signal transduction. 3. 1,3,5-Trihydroxy-4-prenylxanthone shows in vitro inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 values of 56.3plusmn;0.4 and 46.0plusmn;0.3 M, respectively.
target
NF-kB | IkB | AP-1 | JNK | ERK | TGF-β/Smad | AChR | IKK
1,3,5-Trihydroxy-4-prenylxanthone Preparation Products And Raw materials
Raw materials
Preparation Products
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1,3,5-Trihydroxy-4-prenylxanthone Suppliers
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View Lastest Price from 1,3,5-Trihydroxy-4-prenylxanthone manufacturers
Shaanxi Dideu Medichem Co. Ltd
- Product
- 1,3,5-Trihydroxy-4-prenylxanthone 53377-61-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 5mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-06
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