ChemicalBook > CAS DataBase List > 1,3,5-Trimethoxybenzene

1,3,5-Trimethoxybenzene

Product Name
1,3,5-Trimethoxybenzene
CAS No.
621-23-8
Chemical Name
1,3,5-Trimethoxybenzene
Synonyms
Benzene, 1,3,5-trimethoxy-;1,3,5-Trimethyoxybenzene;PHLOROGLUCINOL TRIMETHYL ETHER;1,3,5-Methoxybenzene;2,4,6-Trimethoxybenzene;1,3,5-Trimethoxybenzene Vetec(TM) reagent grade, 98%;Phloroglucinol trimethyl ether, 3,5-Dimethoxyanisole;1,3,5-TriMetho;TRISMETHOXYBENZENE;5-TriMethoxybenzene
CBNumber
CB0371005
Molecular Formula
C9H12O3
Formula Weight
168.19
MOL File
621-23-8.mol
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1,3,5-Trimethoxybenzene Property

Melting point:
50-53 °C (lit.)
Boiling point:
255 °C (lit.)
Density 
1,126g/cm
refractive index 
1,533
Flash point:
186 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
methanol: 0.1 g/mL, clear, colorless
form 
Crystalline Powder
color 
White to cream
Water Solubility 
insoluble
BRN 
1307993
InChIKey
LKUDPHPHKOZXCD-UHFFFAOYSA-N
LogP
1.605 (est)
CAS DataBase Reference
621-23-8(CAS DataBase Reference)
NIST Chemistry Reference
1,3,5-Trimethoxybenzene(621-23-8)
EPA Substance Registry System
1,3,5-Trimethoxybenzene (621-23-8)
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Safety

Hazard Codes 
Xn,F
Risk Statements 
22-20/21/22
Safety Statements 
24/25-36-26
RIDADR 
1325
WGK Germany 
3
RTECS 
DC2810000
Hazard Note 
Flammable Solid/Harmful
TSCA 
Yes
HazardClass 
4.1
PackingGroup 
III
HS Code 
29093090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
138827
Product name
1,3,5-Trimethoxybenzene
Purity
ReagentPlus , ≥99%
Packaging
10g
Price
$36
Updated
2024/03/01
Sigma-Aldrich
Product number
138827
Product name
1,3,5-Trimethoxybenzene
Purity
ReagentPlus , ≥99%
Packaging
50g
Price
$110
Updated
2024/03/01
TCI Chemical
Product number
P0250
Product name
1,3,5-Trimethoxybenzene
Purity
>98.0%(GC)
Packaging
25g
Price
$37
Updated
2024/03/01
TCI Chemical
Product number
P0250
Product name
1,3,5-Trimethoxybenzene
Purity
>98.0%(GC)
Packaging
100g
Price
$111
Updated
2024/03/01
Alfa Aesar
Product number
A13981
Product name
1,3,5-Trimethoxybenzene, 99%
Packaging
10g
Price
$32.4
Updated
2024/03/01
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1,3,5-Trimethoxybenzene Chemical Properties,Usage,Production

Chemical Properties

white to cream crystalline powder. Insoluble in water.

Uses

1,3,5-Trimethoxybenzene is a major scent component of the Chinese rose odour. 1,3,5-Trimethoxybenzene is also a useful synthetic intermediate and is used to synthesize triaryl- and triheteroarylmethanes.

Definition

ChEBI: 1,3,5-trimethoxybenzene is a methoxybenzene carrying methoxy groups at positions 1, 3 and 5. It has been found to be a biomarker of flavonoid consumption in humans. It has a role as a biomarker and a human xenobiotic metabolite.

General Description

1,3,5-Trimethoxybenzene effectively cleaves p-methoxybenzyl protecting group on various alcohols and acids. It is the major scent compound present in Chinese rose species.

Synthesis

A solution of anhydrous phloroglucinol (6.3 g,0.05 mole) in dryacetone (100 ml) is refluxed for 6 hr under anhydrous conditions withdimethyl sulphate (15. 6 ml,20.8 g, 0.165 mole) in presence of ignitedpotassium carbonate (40 g).The mixture is filtered, and the inorganic saltswashed with hot acetone (2 × 20 ml). The combined acetone solution isdistilled and the residue macerated with crushed ice. It is extracted withether, the ether extracts washed with sodium hydroxide solution (5%),water,dried (sodium sulphate) and distilled. Yield 1,3,5-Trimethoxybenzene 6 g (71.4 %).M.p 52-3° (lit. m.p.52-53°).

Solubility in organics

Soluble in Methanol, Ether, Ethanol, Benzene.

Solubility in water

Insoluble

Purification Methods

Sublime it under vacuum. [Beilstein 6 III 635, 6 IV 7362.]

1,3,5-Trimethoxybenzene Preparation Products And Raw materials

Raw materials

Preparation Products

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1,3,5-Trimethoxybenzene Suppliers

Kaifeng Mingren Pharmaceutical Co.,LTD
Tel
0371-65741762
Fax
QQ:2860768577
Email
sales@hasunny.com
Country
China
ProdList
2380
Advantage
58
Zheda Panaco (Shandong) Chemical Enginering Co., Ltd.
Tel
0530-8865559 13805730994;
Fax
0530-8850005
Email
panaco@zhedachem.com
Country
China
ProdList
172
Advantage
58
Zheda Panaco Chemical Engineering Co., Ltd
Tel
0571-86770761 13805730994;
Fax
+0571-87984136
Email
zhedapanaco02@zhedachem.com
Country
China
ProdList
100
Advantage
60
Zhejiang zetian fine chemical co. LTD
Tel
0571-87322520 18957127338
Fax
QQ:800182836
Email
sales@zetchem.com
Country
China
ProdList
451
Advantage
58
Zhejiang Karry Pharmachem Co., Ltd.
Tel
19157666807
Email
info@karrypharma.com
Country
China
ProdList
37
Advantage
58
HANGZHOU KINSOCHEM PHARMA CO.,LTD
Tel
0571-56950601,56950602 15957107654
Fax
0571-56950610
Email
951594434@qq.com
Country
China
ProdList
46
Advantage
55
Beijing Wisdom Chemicals Co., Ltd.
Tel
010-59777827 13701052487
Email
sales1@wisdomchem.com
Country
China
ProdList
244
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
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View Lastest Price from 1,3,5-Trimethoxybenzene manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
1,3,5-Trimethoxybenzene 621-23-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-04
Hebei Weibang Biotechnology Co., Ltd
Product
1,3,5-Trimethoxybenzene 621-23-8
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 TON
Release date
2024-11-01
Hebei Yanxi Chemical Co., Ltd.
Product
1,3,5-Trimethoxybenzene 621-23-8
Price
US $20.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20mt/mon
Release date
2023-09-04

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