ChemicalBook > CAS DataBase List > 5-(piperazin-1-yl)benzofuran-2-carboxylic acid

5-(piperazin-1-yl)benzofuran-2-carboxylic acid

Product Name
5-(piperazin-1-yl)benzofuran-2-carboxylic acid
CAS No.
183288-47-3
Chemical Name
5-(piperazin-1-yl)benzofuran-2-carboxylic acid
Synonyms
Vilazodone Impurity 28;1-(2-Carboxybenzofuran-5-yl)piperazine;5-(1-Piperazinyl)benzofuran-2-carboxylic acid;5-(1-piperazinyl)-2-Benzofurancarboxylic acid;5-(piperazin-1-yl)benzofuran-2-carboxylic acid;5-(Piperazine-1-yl)benzofuran-2-carboxylic acid;2-Benzofurancarboxylic acid, 5-(1-piperazinyl)-;4-[5-(Piperazine-1-yl) benzofuran-2-carboxylic acid
CBNumber
CB52533909
Molecular Formula
C13H14N2O3
Formula Weight
246.26
MOL File
183288-47-3.mol
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5-(piperazin-1-yl)benzofuran-2-carboxylic acid Property

Melting point:
>209° C (dec.)
Density 
1.315
storage temp. 
2-8°C
solubility 
Acidic DMSO (Slightly)
form 
Solid
color 
Pale Brown to Light Brown
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H290May be corrosive to metals

H314Causes severe skin burns and eye damage

Precautionary statements

P234Keep only in original container.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P390Absorb spillage to prevent material damage.

P405Store locked up.

P406Store in corrosive resistant/… container with a resistant inner liner.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
P480625
Product name
5-(1-Piperazinyl)benzofuran-2-carboxylicAcid
Packaging
250mg
Price
$105
Updated
2021/12/16
TRC
Product number
P480625
Product name
5-(1-Piperazinyl)benzofuran-2-carboxylicAcid
Packaging
1g
Price
$375
Updated
2021/12/16
TRC
Product number
P480625
Product name
5-(1-Piperazinyl)benzofuran-2-carboxylicAcid
Packaging
2.5g
Price
$790
Updated
2021/12/16
TRC
Product number
P480625
Product name
5-(1-Piperazinyl)benzofuran-2-carboxylicAcid
Packaging
5g
Price
$1410
Updated
2021/12/16
ChemScene
Product number
CS-M1855
Product name
2-Benzofurancarboxylicacid,5-(1-piperazinyl)-
Purity
98.75%
Packaging
250mg
Price
$65
Updated
2021/12/16
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5-(piperazin-1-yl)benzofuran-2-carboxylic acid Chemical Properties,Usage,Production

Uses

5-(1-Piperazinyl)benzofuran-2-carboxylic Acid is an intermediate in the synthesis of Vilazodone (V265000), a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression.

5-(piperazin-1-yl)benzofuran-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(piperazin-1-yl)benzofuran-2-carboxylic acid Suppliers

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183288-47-3, 5-(piperazin-1-yl)benzofuran-2-carboxylic acidRelated Search:

1-BENZOFURAN-5-AMINE 1H-Indole-5-carbonitrile, 3-(4-hydroxybutyl)- VILAZODONE Vilazodone-d8 5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-Benzofurancarboxylic acid 2-Benzofurancarboxylic acid, 5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-, ethyl ester Vilazodone Impurity 24 ISO-PROPYLCHLOROBUTYRATE 3-(4-Chloro-1-hydroxybutyl)-1H-indole-5-carbonitrile

  • Vilazodone Impurity 28
  • 2-Benzofurancarboxylic acid, 5-(1-piperazinyl)-
  • 5-(1-piperazinyl)-2-Benzofurancarboxylic acid
  • 5-(Piperazine-1-yl)benzofuran-2-carboxylic acid
  • 5-(piperazin-1-yl)benzofuran-2-carboxylic acid
  • 4-[5-(Piperazine-1-yl) benzofuran-2-carboxylic acid
  • 5-(1-Piperazinyl)benzofuran-2-carboxylic acid
  • 1-(2-Carboxybenzofuran-5-yl)piperazine
  • 183288-47-3
  • Intermediates