ChemicalBook > CAS DataBase List > GW 627368X

GW 627368X

Product Name
GW 627368X
CAS No.
439288-66-1
Chemical Name
GW 627368X
Synonyms
CS-1654;GW 627368;GW 627368X;GW627368(GW627368X);GW 627368;GW-627368;GW627368;GW-627368X;GW627368X;GW 627368X;inhibit,Inhibitor,Prostaglandin Receptor,GW627368,GW 627368,GW-627368;N-(benzenesulfonyl)-2-[4-(4,9-diethoxy-3-oxo-1H-benzo[f]isoindol-2-yl)phenyl]acetamide;2-(4-(4,9-Diethoxy-1-oxo-1H-benzo[f]isoindol-2(3H)-yl)phenyl)-N-(phenylsulfonyl)acetamide;N-(benzenesulfonyl)-2-(4-{4,9-diethoxy-1-oxo-1H,2H,3H-benzo[f]isoindol-2-yl}phenyl)acetamide;4-(4,9-Diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)benzeneacetamide
CBNumber
CB52591190
Molecular Formula
C30H28N2O6S
Formula Weight
544.62
MOL File
439288-66-1.mol
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GW 627368X Property

Density 
1.327±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMSO : 100 mg/mL (183.61 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form 
Powder
pka
5.25±0.10(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10009162
Product name
GW 627368X
Purity
≥96%
Packaging
1mg
Price
$59
Updated
2024/03/01
Cayman Chemical
Product number
10009162
Product name
GW 627368X
Purity
≥96%
Packaging
5mg
Price
$253
Updated
2024/03/01
Cayman Chemical
Product number
10009162
Product name
GW 627368X
Purity
≥96%
Packaging
10mg
Price
$448
Updated
2024/03/01
Cayman Chemical
Product number
10009162
Product name
GW 627368X
Purity
≥96%
Packaging
25mg
Price
$979
Updated
2024/03/01
Tocris
Product number
4668
Product name
GW627368
Purity
≥98%(HPLC)
Packaging
50
Price
$1122
Updated
2021/12/16
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GW 627368X Chemical Properties,Usage,Production

Description

The effects of prostaglandin E2 (PGE2) are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4. GW 627368X is a potent and selective competitive antagonist of the EP4 receptor with additional human TP receptor affinity. In competition radioligand bioassays, GW 627368X had affinity for human EP4 and TP receptors with Ki values of 100 nM and 158 nM, respectively. Affinity for all other human prostanoid receptors is >5.0 μM. In human washed platelets, GW 627368X produced 100% inhibition of U-46619 (EC100)-induced aggregation at a concentration of 10 μM.

Uses

GW 627368 is a selective EP4 receptor competitive antagonist.

GW 627368X Preparation Products And Raw materials

Raw materials

Preparation Products

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GW 627368X Suppliers

China 50 United Kingdom 1 United States 14 Global 65
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4566
Advantage
55
D&C Chemicals
Tel
+86-21-58447131
Fax
+86-21-61642470
Email
1724405207@qq.com
Country
China
ProdList
472
Advantage
55
Zhengzhou Saifun Biotechnology Co., Ltd.
Tel
022-60688926
Country
China
ProdList
60
Advantage
55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Twochem Co.Ltd
Tel
021-021-58111628 15800915896
Fax
QQ 3285589261
Email
sales@twochem.com
Country
China
ProdList
304
Advantage
55
ATK CHEMICAL COMPANY LIMITED
Tel
021-51619050 13301662590
Fax
+86-21-51619052
Email
mandy@atkchemical.com
Country
China
ProdList
10200
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
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View Lastest Price from GW 627368X manufacturers

Career Henan Chemical Co
Product
GW 627368X 439288-66-1
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kg
Release date
2020-01-13

439288-66-1, GW 627368XRelated Search:

GW 4064 GW843682, 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide GW-6604 Carbamic acid, N-[(5S)-5-[[(2R,3S)-3-(formylhydroxyamino)-2-(2-methylpropyl)-1-oxohexyl]amino]-6-oxo-6-(2-thiazolylamino)hexyl]-, phenylmethyl ester GW 6471 GW806742X ONO-AE3-208 CJ 033466 CJ-21058 CJ-42794 L-161,982 Grapiprant

  • GW 627368X
  • GW 627368
  • 4-(4,9-Diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)benzeneacetamide
  • 2-[4-(4,9-Diethoxy-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl)phenyl]-N-(phenylsulfonyl)acetamide
  • GW 627368;GW-627368;GW627368;GW-627368X;GW627368X;GW 627368X
  • CS-1654
  • GW627368(GW627368X)
  • N-(benzenesulfonyl)-2-[4-(4,9-diethoxy-3-oxo-1H-benzo[f]isoindol-2-yl)phenyl]acetamide
  • 2-(4-(4,9-Diethoxy-1-oxo-1H-benzo[f]isoindol-2(3H)-yl)phenyl)-N-(phenylsulfonyl)acetamide
  • Benzeneacetamide, 4-(4,9-diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)-
  • inhibit,Inhibitor,Prostaglandin Receptor,GW627368,GW 627368,GW-627368
  • N-(benzenesulfonyl)-2-(4-{4,9-diethoxy-1-oxo-1H,2H,3H-benzo[f]isoindol-2-yl}phenyl)acetamide
  • 439288-66-1
  • Inhibitors