Miriplatin
- Product Name
- Miriplatin
- CAS No.
- 141977-79-9
- Chemical Name
- Miriplatin
- Synonyms
- Mibo;Miripla;Miplatin;SM 11355;[(1R,2R)-1,2-Cyclohexanediamine]bis(myristato)platinum;(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis...;Miriplatin,SM11355,inhibit,Inhibitor,SM 11355,DNA Alkylator/Crosslinker;(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN1,κN2]bis(tetradecanoato-κO)platinum;(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis(myristato-kappaO)platinum;(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis(myristato-kappaO)platinum(II)
- CBNumber
- CB52612602
- Molecular Formula
- C34H66N2O4Pt
- Formula Weight
- 762
- MOL File
- 141977-79-9.mol
Miriplatin Property
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- solubility
- DMF : < 1 mg/mL (insoluble)
- form
- Solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SML2720
- Product name
- Miriplatin
- Purity
- >97.5% (Pt analysis)
- Packaging
- 10MG
- Price
- $75.4
- Updated
- 2024/03/01
- Product number
- SML2720
- Product name
- Miriplatin
- Purity
- >97.5% (Pt analysis)
- Packaging
- 50MG
- Price
- $306
- Updated
- 2024/03/01
- Product number
- CS-3921
- Product name
- Miriplatin
- Purity
- >98.0%
- Packaging
- 100mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- 3854AH
- Product name
- Miriplatin
- Packaging
- 50mg
- Price
- $236
- Updated
- 2021/12/16
- Product number
- CS-3921
- Product name
- Miriplatin
- Purity
- >98.0%
- Packaging
- 10mg
- Price
- $70
- Updated
- 2021/12/16
Miriplatin Chemical Properties,Usage,Production
Uses
Miplatin is a platinum-based anticancer drug developed by Japan's Sumitomo Pharmaceutical Co., Ltd. It is used in the treatment of liver cancer, malignant lymphoma, non-small cell lung cancer, small cell lung cancer and superficial bladder cancer.
Biological Activity
Miriplatin (SM-11355) is a derivative of cisplatin containing myristate as a carrier ligand. It is a novel lipophilic platinum complex for the treatment of hepatocellular carcinoma.
in vitro
Miriplatin (SM-11355) suspended in LPD (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis.
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in vivo
Miriplatin (SM-11355) (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells. Miriplatin/LPD (400 μg/head) significantly reduces tumor growth rates the growth of tumor in rats bearing AH109A cells.
Miriplatin Preparation Products And Raw materials
Raw materials
Preparation Products
Miriplatin Suppliers
- Tel
- 44-20819178-90 02081917890
- Fax
- (0)2080432064
- info@novachemistry.com
- Country
- United Kingdom
- ProdList
- 4381
- Advantage
- 58
View Lastest Price from Miriplatin manufacturers
- Product
- Miriplatin 141977-79-9
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 90.0% min
- Supply Ability
- 100kgs/month
- Release date
- 2023-06-12
- Product
- Miriplatin 141977-79-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- Miriplatin 141977-79-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08