ChemicalBook > CAS DataBase List > Miriplatin

Miriplatin

Product Name
Miriplatin
CAS No.
141977-79-9
Chemical Name
Miriplatin
Synonyms
Mibo;Miripla;Miplatin;SM 11355;[(1R,2R)-1,2-Cyclohexanediamine]bis(myristato)platinum;(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis...;Miriplatin,SM11355,inhibit,Inhibitor,SM 11355,DNA Alkylator/Crosslinker;(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN1,κN2]bis(tetradecanoato-κO)platinum;(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis(myristato-kappaO)platinum;(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis(myristato-kappaO)platinum(II)
CBNumber
CB52612602
Molecular Formula
C34H66N2O4Pt
Formula Weight
762
MOL File
141977-79-9.mol
More
Less

Miriplatin Property

storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
DMF : < 1 mg/mL (insoluble)
form 
Solid
color 
White to off-white
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2720
Product name
Miriplatin
Purity
>97.5% (Pt analysis)
Packaging
10MG
Price
$75.4
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2720
Product name
Miriplatin
Purity
>97.5% (Pt analysis)
Packaging
50MG
Price
$306
Updated
2024/03/01
ChemScene
Product number
CS-3921
Product name
Miriplatin
Purity
>98.0%
Packaging
100mg
Price
$220
Updated
2021/12/16
AK Scientific
Product number
3854AH
Product name
Miriplatin
Packaging
50mg
Price
$236
Updated
2021/12/16
ChemScene
Product number
CS-3921
Product name
Miriplatin
Purity
>98.0%
Packaging
10mg
Price
$70
Updated
2021/12/16
More
Less

Miriplatin Chemical Properties,Usage,Production

Uses

Miplatin is a platinum-based anticancer drug developed by Japan's Sumitomo Pharmaceutical Co., Ltd. It is used in the treatment of liver cancer, malignant lymphoma, non-small cell lung cancer, small cell lung cancer and superficial bladder cancer.

Biological Activity

Miriplatin (SM-11355) is a derivative of cisplatin containing myristate as a carrier ligand. It is a novel lipophilic platinum complex for the treatment of hepatocellular carcinoma.

in vitro

Miriplatin (SM-11355) suspended in LPD (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis.

< b>

in vivo

Miriplatin (SM-11355) (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells. Miriplatin/LPD (400 μg/head) significantly reduces tumor growth rates the growth of tumor in rats bearing AH109A cells.

Miriplatin Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Miriplatin Suppliers

MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
More
Less

View Lastest Price from Miriplatin manufacturers

Hangzhou ICH Biofarm Co., Ltd
Product
Miriplatin 141977-79-9
Price
US $0.00-0.00/g
Min. Order
1g
Purity
90.0% min
Supply Ability
100kgs/month
Release date
2023-06-12
Zhuozhou Wenxi import and Export Co., Ltd
Product
Miriplatin 141977-79-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Miriplatin 141977-79-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

141977-79-9, MiriplatinRelated Search:


  • [(1R,2R)-1,2-Cyclohexanediamine]bis(myristato)platinum
  • Miripla
  • SM 11355
  • (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis(myristato-kappaO)platinum
  • (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis(myristato-kappaO)platinum(II)
  • (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis...
  • (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN1,κN2]bis(tetradecanoato-κO)platinum
  • Mibo
  • Miriplatin,SM11355,inhibit,Inhibitor,SM 11355,DNA Alkylator/Crosslinker
  • Miplatin
  • 141977-79-9
  • C34H68N2O4Pt