BAY 80-6946 (Copanlisib)

Product Name: BAY 80-6946 (Copanlisib)
CAS No.: 1032568-63-0
Chemical Name: BAY 80-6946 (Copanlisib)
Synonyms: Copanlisib;BAY80-6946;CS-2321;Aliqopa);Copanlisib base;Copanlisib free base;Copanlisib(BAY80-6946);BAY 80-6946 (BAY80-6946;BAY 80-6946 (Copanlisib);BAY 80-6946 (Copanlisib) USP/EP/BP
CBNumber: CB52616024
Molecular Formula: C23H28N8O4
Formula Weight: 480.52
MOL File: 1032568-63-0.mol

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BAY 80-6946 (Copanlisib) Property

Density: 1.51
storage temp.: Store at -20°C
solubility: insoluble in DMSO; insoluble in H2O; insoluble in EtOH
form: solid
pka: 8.42±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 20354
Product name: Copanlisib
Purity: ≥98%
Packaging: 5mg
Price: $61
Updated: 2024/03/01

Cayman Chemical

Product number: 20354
Product name: Copanlisib
Purity: ≥98%
Packaging: 1mg
Price: $72
Updated: 2023/06/20

Cayman Chemical

Product number: 20354
Product name: Copanlisib
Purity: ≥98%
Packaging: 10mg
Price: $91
Updated: 2024/03/01

TRC

Product number: B119060
Product name: BAY80-6946
Packaging: 10mg
Price: $395
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BC164810
Product name: Copanlisib
Packaging: 25mg
Price: $450
Updated: 2021/12/16

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BAY 80-6946 (Copanlisib) Chemical Properties,Usage,Production

Uses

BAY 80-6946 is a highly selective intravenous PI3K inhibitor with potent p110α and p110δ activities in tumor cell lines and xenograft models.

Definition

ChEBI: Copanlisib is an imidazoquinazoline that is 2,3-dihydroimidazo[1,2-c]quinazoline substituted by (2-aminopyrimidine-5-carbonyl)amino, methoxy, and 3-(morpholin-4-yl)propoxy groups at positions 5, 7 and 8, respectively. It is a intravenous pan-class I PI3K inhibitor used for the treatment of relapsed follicular lymphoma in patients who have received at least 2 prior systemic therapies. It has a role as an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor, an antineoplastic agent and an apoptosis inducer. It is a member of morpholines, an aromatic ether, a diether, a tertiary amino compound, a secondary carboxamide, a pyrimidinecarboxamide, an aminopyrimidine and an imidazoquinazoline.

BAY 80-6946 (Copanlisib) Preparation Products And Raw materials

Raw materials

Preparation Products

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BAY 80-6946 (Copanlisib) Suppliers

China 126 India 5 United States 16 Global 147

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2923
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WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.

Tel: 17702719238 17702719238
Email: sales@sun-shinechem.com
Country: China
ProdList: 905
Advantage: 64

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
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Jinan Trio PharmaTech Co., Ltd.

Tel: +86 (531) 88811783
Fax: +86 (531) 55696010 QQ 1762738062
Email: sales@trio-pharmatech.com (International market)
Country: China
ProdList: 1856
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Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4647
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T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
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Artis Chemistry (Shanghai) Co. Ltd.

Tel: 86-21-60936353
Fax: 86-21-60936352
Country: China
ProdList: 336
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Dtchem Laboratories,（Gan Su）Co.,Ltd.

Tel: 18993966060
Fax: 0943-8288977
Email: sales@techbiochem.com
Country: China
ProdList: 944
Advantage: 61

NCE Biomedical Co.,Ltd.

Tel: 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax: +86-27-87599188
Country: China
ProdList: 1494
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
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View Lastest Price from BAY 80-6946 (Copanlisib) manufacturers

Career Henan Chemical Co

Product: BAY 80-6946 (Copanlisib) 1032568-63-0
Price: US $2.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-23

1032568-63-0, BAY 80-6946 (Copanlisib)Related Search:

Salirasib BKM120 (NVP-BKM120, Buparlisib) Alpelisib (BYL719) Pictilisib IPI 145 CAL-101 BEZ235 (NVP-BEZ235, Dactolisib)

BAY 80-6946 (Copanlisib)

7-methoxy-8-(3-morpholinopropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine

BAY80-6946

2-Amino-N-[2,3-dihydro-7-methoxy-8-[3-(4-morpholinyl)propoxy]imidazo[1,2-c]quinazolin-5-yl]-5-pyrimidinecarboxamide

Copanlisib

5-Pyrimidinecarboxamide, 2-amino-N-[2,3-dihydro-7-methoxy-8-[3-(4-morpholinyl)propoxy]imidazo[1,2-c]quinazolin-5-yl]-

Copanlisib(BAY80-6946)

Copanlisib, 98%, an ATP-competitive selective class-I PI3 kinases inhibitor

Copanlisib base

BAY 80-6946 (BAY80-6946

CS-2321

BAY 80-6946; BAY80-6946; BAY-80-6946; BAY806946; BAY-806946; BAY 806946; COPANLISIB FREE BASE

Copanlisib free base

BAY 80-6946 (Copanlisib) USP/EP/BP

Aliqopa)

2-Amino-N-(7-methoxy-8-(3-morpholinopropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)pyrimidine-5-carboxamide

1032568-63-0

C23H28N8O4

Inhibitors

Akt

mTOR

PI3K

PI3K/Akt/mTOR