BenzaMide, 3-[[4-[(5-hydroxy-2-Methylphenyl)aMino]-2-pyriMidinyl]aMino]-

Product Name: BenzaMide, 3-[[4-[(5-hydroxy-2-Methylphenyl)aMino]-2-pyriMidinyl]aMino]-
CAS No.: 944795-06-6
Chemical Name: BenzaMide, 3-[[4-[(5-hydroxy-2-Methylphenyl)aMino]-2-pyriMidinyl]aMino]-
Synonyms: Lck inhibitor 2;Lck inhibitor 2/944795-06-6;3-[[4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl]amino]-;3-[[4-(5-hydroxy-2-methylanilino)pyrimidin-2-yl]amino]benzamide;3-[[4-[(5-Hydroxy-2-methylphenyl)amino]-2-pyrimidinyl]amino]benzamide;BenzaMide, 3-[[4-[(5-hydroxy-2-Methylphenyl)aMino]-2-pyriMidinyl]aMino]-
CBNumber: CB52627387
Molecular Formula: C18H17N5O2
Formula Weight: 335.36
MOL File: 944795-06-6.mol

More

Less

BenzaMide, 3-[[4-[(5-hydroxy-2-Methylphenyl)aMino]-2-pyriMidinyl]aMino]- Property

Boiling point:: 615.3±65.0 °C(Predicted)
Density: 1.389±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: DMSO : 20 mg/mL (59.64 mM; Need ultrasonic)
form: Powder
pka: 9.92±0.18(Predicted)
color: Light yellow to yellow

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-1491
Product name: Lckinhibitor2
Purity: 99.73%
Packaging: 5mg
Price: $150
Updated: 2021/12/16

ChemScene

Product number: CS-1491
Product name: Lckinhibitor2
Purity: 99.73%
Packaging: 10mg
Price: $240
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611762
Product name: Lck inhibitor 2
Packaging: 10mg
Price: $584.8
Updated: 2021/12/16

ChemScene

Product number: CS-1491
Product name: Lckinhibitor2
Purity: 99.73%
Packaging: 50mg
Price: $680
Updated: 2021/12/16

ChemScene

Product number: CS-1491
Product name: Lckinhibitor2
Purity: 99.73%
Packaging: 100mg
Price: $950
Updated: 2021/12/16

More

Less

BenzaMide, 3-[[4-[(5-hydroxy-2-Methylphenyl)aMino]-2-pyriMidinyl]aMino]- Chemical Properties,Usage,Production

Uses

Lck inhibitor 2 is a multi-target tyrosine kinase inhibitor with IC50s of 13nM, 9nM, 3nM, 26nM and 2nM for Lck, Btk, Lyn, Btk and Txk respectively.

References

[1] Bamborough, et al. Assessment of Chemical Coverage of Kinome Space and Its Implications for Kinase Drug Discovery. Journal of Medicinal Chemistry (2008), 51(24), 7898-7914. DOI:10.1021/jm8011036
[2] Bamborough, Paul, et al. N-4-Pyrimidinyl-1H-indazol-4-amine inhibitors of Lck: Indazoles as phenol isosteres with improved pharmacokinetics. Bioorganic & Medicinal Chemistry Letters (2007), 17(15), 4363-4368. DOI:10.1016/j.bmcl.2007.04.029
[3] Awale, Mahendra, et al. Molecular docking guided 3D-QSAR CoMFA analysis of N-4-Pyrimidinyl-1H-indazol-4-amine inhibitors of leukocyte-specific protein tyrosine kinase. Journal of Molecular Modeling (2008), 14(10), 937-947. DOI:10.1007/s00894-008-0334-8

BenzaMide, 3-[[4-[(5-hydroxy-2-Methylphenyl)aMino]-2-pyriMidinyl]aMino]- Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

BenzaMide, 3-[[4-[(5-hydroxy-2-Methylphenyl)aMino]-2-pyriMidinyl]aMino]- Suppliers

China 39 United States 8 Global 47

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 40000
Advantage: 60

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3866
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 86249
Advantage: 60

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9505
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32467
Advantage: 58

944795-06-6, BenzaMide, 3-[[4-[(5-hydroxy-2-Methylphenyl)aMino]-2-pyriMidinyl]aMino]-Related Search:

Chlorotrimethylsilane 3'-Hydroxyacetophenone 2-HYDROXYACETOPHENONE Dihydroxybenzoic acid Acetaminophen 2'-Hydroxyacetophenone

BenzaMide, 3-[[4-[(5-hydroxy-2-Methylphenyl)aMino]-2-pyriMidinyl]aMino]-

Lck inhibitor 2

3-[[4-[(5-Hydroxy-2-methylphenyl)amino]-2-pyrimidinyl]amino]benzamide

3-[[4-(5-hydroxy-2-methylanilino)pyrimidin-2-yl]amino]benzamide

3-[[4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl]amino]-

Lck inhibitor 2/944795-06-6

944795-06-6