Oxamic acid sodium salt

Product Name: Oxamic acid sodium salt
CAS No.: 565-73-1
Chemical Name: Oxamic acid sodium salt
Synonyms: SODIUM OXAMATE;oxamate sodium;Grass sodiuM acid;oxamic acid sodium;Oxamate Sodium Salt;OXAMIC ACID SODIUM SALT;sodium carbamoylformate;sodiuM 2-aMino-2-oxoacetate;Oxamic acid, sodium salt,98%;AMINOOXOACETIC ACID SODIUM SALT
CBNumber: CB5262762
Molecular Formula: C2H2NNaO3
Formula Weight: 111.03
MOL File: 565-73-1.mol

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Oxamic acid sodium salt Property

Melting point:: 300 °C
storage temp.: Inert atmosphere,Room Temperature
solubility: PBS (pH 7.2): 10 mg/ml
form: solid
color: White to off-white
Water Solubility: Soluble in water (10 mg/ml).
BRN: 6538153
InChI: InChI=1S/C2H3NO3.Na/c3-1(4)2(5)6;/h(H2,3,4)(H,5,6);/q;+1/p-1
InChIKey: RQVZIJIQDCGIKI-UHFFFAOYSA-M
SMILES: C(=O)(N)C([O-])=O.[Na+]
CAS DataBase Reference: 565-73-1(CAS DataBase Reference)
EPA Substance Registry System: Sodium oxamate (565-73-1)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 10
TSCA: Yes
HS Code: 29241990

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: O2751
Product name: Sodium oxamate
Purity: ≥98%
Packaging: 5G
Price: $136
Updated: 2024/03/01

Sigma-Aldrich

Product number: O2751
Product name: Sodium oxamate
Purity: ≥98%
Packaging: 25G
Price: $569
Updated: 2024/03/01

Sigma-Aldrich

Product number: O2751
Product name: Sodium oxamate
Purity: ≥98%
Packaging: 100G
Price: $987
Updated: 2024/03/01

Alfa Aesar

Product number: A16532
Product name: Oxamic acid sodium salt, 98%
Packaging: 5g
Price: $42.6
Updated: 2024/03/01

Alfa Aesar

Product number: A16532
Product name: Oxamic acid sodium salt, 98%
Packaging: 25g
Price: $112
Updated: 2024/03/01

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Oxamic acid sodium salt Chemical Properties,Usage,Production

Description

Oxamic acid sodium salt is a lactate dehydrogenase-A (LDH-A) inhibitor. Oxamic acid sodium salt shows anti-tumor activity, and anti-proliferative activity against cancer cells, and can induce apoptosis. Oxamic acid suppresses the proliferation, migration and invasion of both A2780 and SKOV3 cells.

Chemical Properties

white crystalline powder

Uses

Oxamic acid sodium salt is a lactate dehydrogenase (LDH) inhibitor. It is a suitable compound to investigate cancer cells that utilize the glycolytic pathway.This compound is suitable for lactate dehydrogenase (LDH) related research. It can be used as an inhibitor of gluconeogenesis useful for anticancer research.

Application

Sodium oxamate, an inhibitor of LDH-C4, prevented the AR induced by lysophosphatidylcholine (LPC) or NADH. Oxamic acid sodium salt is an lactic acid dehydrogenase. Sperm suspension and cytosol fraction activities were inhibited by sodium oxamate. As cancer cells are often dependent on glycolysis for ATP production, sodium oxamate has implications as an anticancer compound.

Biochem/physiol Actions

Sodium oxamate influences the fatty acid metabolism. It might be useful for the treatment of diabetes.

in vitro

Oxamic acid suppresses the proliferation, migration and invasion of both A2780 and SKOV3 cells. Oxamic acid (10 μM; 24-72 h) inhibits cell proliferation in a dose- and time-dependent manner in both NPC cancer cells. Oxamic acid (0-100 mM; 24 h) induces cell cycle arrest in the G2/M phase in CNE-1 and CNE-2 cells. Oxamic acid (0-100 mM; 48 h) induces apoptosis via caspase-3 activation and the mitochondrial pathway in NPC cells. Oxamic acid (0-100 mM; 24 h) increases ROS levels in NPC cells.

Oxamic acid sodium salt Preparation Products And Raw materials

Raw materials

Ethyl chlorooxoacetate Ethanol Toluene Diethyl oxalate Tetrahydrofuran Ethyl acetate Sodium hydroxide ETHYL OXAMATE Ammonia

Preparation Products

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Oxamic acid sodium salt Suppliers

Austria 1 Belgium 1 Canada 1 China 137 Europe 2 France 1 Germany 6 India 5 Japan 3 Switzerland 2 The Netherlands 1 United Kingdom 4 United States 29 Global 193

Shanghai Hengmao Biotechnology Co. , Ltd.

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New Energy Chemicals

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J & K SCIENTIFIC LTD.

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Alfa Aesar

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Energy Chemical

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Syntechem Co.,Ltd

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Sinopharm Chemical Reagent Co,Ltd.

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View Lastest Price from Oxamic acid sodium salt manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Oxamic acid sodium salt 565-73-1
Price: US $0.00/G
Min. Order: 50G
Purity: 98%min
Supply Ability: 30kg/month
Release date: 2023-02-07

Career Henan Chemical Co

Product: OXAMIC ACID SODIUM SALT 565-73-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98% HPLC
Supply Ability: 10 tons/month
Release date: 2020-01-09

565-73-1, Oxamic acid sodium saltRelated Search:

Sodium phytate ETHYL OXAMATE Ferric ammonium oxalate trihydrate Stannous oxalate POTASSIUM TITANIUM OXALATE DIHYDRATE Ferrous oxalate dihydrate Potassium binoxalate EC 2.7.1.40 Oxalic acid Oxamic acid SODIUM GLYOXYLATE Oxamic acid sodium salt

aminooxo-aceticacimonosodiumsalt

AMINOOXOACETIC ACID SODIUM SALT

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OXAMIC ACID SODIUM SALT

SODIUM OXAMATE

oxamic acid sodium

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Aminooxoacetic acid sodium salt, Oxalic acid monoamide sodium salt, Oxamic acid sodium salt

2-Amino-2-oxoacetic acid sodium salt

Oxamic acid, sodium salt,98%

Sodium oxamate,Aminooxoacetic acid sodium salt, Oxalic acid monoamide sodium salt, Oxamic acid sodium salt

Grass sodiuM acid

sodiuM 2-aMino-2-oxoacetate

Oxamate Sodium Salt

Acetic acid,2-amino-2-oxo-, sodium salt (1:1)

OXAMIC ACID SODIUM SALT USP/EP/BP

oxamate sodium

sodium carbamoylformate

565-73-1

H2NCOCO2Na

NH2COCOONa

C2H2NNaO3

C2H2NO3Na

L to O

Lactic dehydrogenase, L-

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