Biotinyl tyramide

Product Name: Biotinyl tyramide
CAS No.: 41994-02-9
Chemical Name: Biotinyl tyramide
Synonyms: Biotinyl TSA;Biotin Tyramide;D-(+)-Biotin-tyramine amide;Biotinyl tyramide, 10 mM in DMSO;N-(4-hydroxyphenethyl)biotinamide;Biotin-Phenol, BP, Biotinyl-Tyramine;TSA,Biotinyl tyramide,inhibit,Inhibitor;(3aS,4S,6aR)-hexahydro-N-[2-(4-hydroxyphenyl)ethyl]-2-oxo-1H...;N-(4-Hydroxyphenethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide;(3aS,4S,6aR)-Hexahydro-N-[2-(4-hydroxyphenyl)ethyl]-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide
CBNumber: CB52638943
Molecular Formula: C18H25N3O3S
Formula Weight: 363.47
MOL File: 41994-02-9.mol

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Biotinyl tyramide Property

Boiling point:: 735.8±60.0 °C(Predicted)
Density: 1.227±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 20 mg/ml)
pka: 10.01±0.15(Predicted)
form: solid
color: White
Appearance: white solid
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChI: InChI=1S/C18H25N3O3S/c22-13-7-5-12(6-8-13)9-10-19-16(23)4-2-1-3-15-17-14(11-25-15)20-18(24)21-17/h5-8,14-15,17,22H,1-4,9-11H2,(H,19,23)(H2,20,21,24)/t14-,15-,17-/m0/s1
InChIKey: VZWXNOBHWODXCW-ZOBUZTSGSA-N
SMILES: C1(=O)N[C@]2([H])[C@H](CCCCC(NCCC3=CC=C(O)C=C3)=O)SC[C@]2([H])N1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2135
Product name: Biotinyl tyramide
Purity: ≥97% (HPLC)
Packaging: 50MG
Price: $202
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML2135
Product name: Biotinyl tyramide
Purity: ≥97% (HPLC)
Packaging: 250MG
Price: $545
Updated: 2025/07/31

TCI Chemical

Product number: B6573
Product name: Biotinyl Tyramide
Packaging: 50MG
Price: $136
Updated: 2025/07/31

TCI Chemical

Product number: B6573
Product name: Biotinyl Tyramide
Packaging: 200MG
Price: $342
Updated: 2025/07/31

Cayman Chemical

Product number: 27997
Product name: Biotinyl Tyramide
Packaging: 10mg
Price: $32
Updated: 2024/03/01

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Biotinyl tyramide Chemical Properties,Usage,Production

Description

Biotinyl tyramide is a reagent that has been used for tyramide signal amplification (TSA) via catalyzed reporter deposition (CARD). In CARD, a reporter enzyme, such as horseradish peroxidase (HRP) conjugated to a secondary antibody, is bound to the target of interest and catalyzes the covalent deposition of biotinyl tyramide to the sample. The sample is then probed by a detector, such as streptavidin-HRP, allowing detection via chromogenic or fluorescent methods. Biotinyl tyramide has been used in immunohistochemistry, ELISA, Western blot, and in situ hybridization applications.

Uses

Biotinyl Tyramide is a Biotin (B389040) derivative, a growth factor present in minute amounts in every living cell. Plays an indispensable role in numerous naturally occurring carboxylation reactions. Occurs mainly bound to proteins or polypeptides. The richest sources are liver, kidney, pancreas, yeast, and milk. The biotin content of cancerous tumors is higher than that of normal tissue.

Solubility in water

Biotinyl tyramide is supplied as a solid. A stock solution may be made by dissolving the biotin tyramide in the solvent of choice, which should be purged with an inert gas. It is soluble in organic solvents such as DMS0 and dimethyl formamide. The solubility of biotinyl tyramide in these solvents is approximately 30 mg/ml.
This product is sparingly soluble in aqueous buffers. For maximum solubility in aqueous buffers, biotinyl tyramide should first be dissolved in DMSO and then diluted with the aqueous buffer of choice. Biotinyl tyramide has a solubility of approximately 0.16 mg/ml in a 1:5 solution of DMSO: PBS(pH 7.2) using this method.

storage

Store at -20°C

References

[1] MARK N. BOBROW. Catalyzed reporter deposition, a novel method of signal amplification application to immunoassays[J]. Journal of immunological methods, 1989, 125 1: Pages 279-285. DOI:10.1016/0022-1759(89)90104-x
[2] MARK F EVANS Kumarasen C Holly A Aliesky. Optimization of biotinyl-tyramide-based in situ hybridization for sensitive background-free applications on formalin-fixed, paraffin-embedded tissue specimens.[J]. BMC Clinical Pathology, 2003, 3 1: 2. DOI:10.1186/1472-6890-3-2
[3] Quantification of a-tubulin by sandwich ELISA with signal amplification through niotinyl-tyramide or immune-PCR
[4] OWEN J EINARSON Dipankar S. Self-biotinylation of DNA G-quadruplexes via intrinsic peroxidase activity.[J]. Nucleic Acids Research, 2017, 45 17: 9813-9822. DOI:10.1093/nar/gkx765
[5] JIWON HWANG Peter J E. Proximity-dependent biotin labelling in yeast using the engineered ascorbate peroxidase APEX2.[J]. Biochemical Journal, 2016, 473 16: 2463-2469. DOI:10.1042/bcj20160106

Biotinyl tyramide Preparation Products And Raw materials

Raw materials

Preparation Products

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Biotinyl tyramide Suppliers

China 105 Germany 1 United Kingdom 1 United States 6 Global 113

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View Lastest Price from Biotinyl tyramide manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Biotinyl Tyramide 41994-02-9
Price: US $2.00-5.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-07-08

Xian confluore Biological Technology Co., Ltd.

Product: Biotinyl Tyramide 41994-02-9
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-30

41994-02-9, Biotinyl tyramideRelated Search:

Vitamin D3 EPA Astemizole (E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT Zileuton 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-2-oxo-N-2-propynyl-, (3aS,4S,6aR)- BIOTIN HPDP N-(3-Azidopropyl)biotinaMide (+)-BIOTIN-EPSILON-AMINOCAPROIC ACID 3-[2-N-(BIOTINYL)AMINOETHYLDITHIO]PROPANOIC ACID Sodium benzenolate Vitamin E BIOTINAMIDOCAPROYL HYDRAZIDE D-Biotin Phenol 3-Aminophenol Biotin-PEG3-NHS ester 2,5-Dioxo-1-pyrrolidinyl 2-[2-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]ethyl carbonate

1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-N-[2-(4-hydroxyphenyl)ethyl]-2-oxo-, (3aS,4S,6aR)-

(3aS,4S,6aR)-Hexahydro-N-[2-(4-hydroxyphenyl)ethyl]-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide

Biotin Tyramide

D-(+)-Biotin-tyramine amide

N-(4-Hydroxyphenethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide

5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-(4-hydroxyphenyl)ethyl]pentanamide

(3aS,4S,6aR)-hexahydro-N-[2-(4-hydroxyphenyl)ethyl]-2-oxo-1H...

TSA,Biotinyl tyramide,inhibit,Inhibitor

Biotinyl TSA

N-(4-hydroxyphenethyl)biotinamide

Biotinyl tyramide, 10 mM in DMSO

Biotin-Phenol, BP, Biotinyl-Tyramine

41994-02-9

Biotin Derivatives, Pharmaceuticals, Intermediates & Fine Chemicals