Boc-NH-PEG4-CH2COOH

Product Name: Boc-NH-PEG4-CH2COOH
CAS No.: 876345-13-0
Chemical Name: Boc-NH-PEG4-CH2COOH
Synonyms: NHBoc-PEG4-CH2COOH;Boc-NH-PEG(3)-COOH;Boc-NH-PEG4-CH2CO0H;Boc-NH-(PEG)4-CH2COOH;t-Boc-N-amido-PEG4-CH2CO2H;Boc-NH-PEG(3)-COOH(16atoMs);t-boc-N-amido-PEG4-acetic acid;14-(Boc-amino)-3,6,9,12-tetraoxatetradecan-1-oic Acid;2,2-Dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azanonadecan-19-oic acid;14-{[(tert-butoxy)carbonyl]amino}-3,6,9,12-tetraoxatetradecanoic acid
CBNumber: CB52648724
Molecular Formula: C15H29NO8
Formula Weight: 351.39
MOL File: 876345-13-0.mol

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Boc-NH-PEG4-CH2COOH Property

Boiling point:: 493.6±40.0 °C(Predicted)
Density: 1.138±0.06 g/cm3(Predicted)
refractive index: n/D 1.4641
storage temp.: -20°C
pka: 3.39±0.10(Predicted)
form: Viscous Liquid
color: Colorless to light yellow
InChI: InChI=1S/C15H29NO8/c1-15(2,3)24-14(19)16-4-5-20-6-7-21-8-9-22-10-11-23-12-13(17)18/h4-12H2,1-3H3,(H,16,19)(H,17,18)
InChIKey: SHMYENBXRNPSOG-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)NCCOCCOCCOCCOCC(O)=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 902551
Product name: BocNH-PEG4-acid
Packaging: 250MG
Price: $264.04
Updated: 2025/07/31

Sigma-Aldrich

Product number: 902551
Product name: BocNH-PEG4-acid
Packaging: 1G
Price: $801
Updated: 2025/07/31

ChemScene

Product number: CS-0025223
Product name: Boc-NH-PEG4-CH2COOH
Purity: ≥97.0%
Packaging: 250mg
Price: $160
Updated: 2021/12/16

BroadPharm

Product number: BP-23531
Product name: t-Boc-N-amido-PEG4-CH2CO2H
Purity: 98%
Packaging: 500mg
Price: $280
Updated: 2021/12/16

AK Scientific

Product number: 9715CS
Product name: 2,2-Dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azanonadecan-19-oicacid
Packaging: 1g
Price: $390
Updated: 2021/12/16

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Boc-NH-PEG4-CH2COOH Chemical Properties,Usage,Production

Description

t-Boc-N-amido-PEG4-CH2CO2H is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Uses

This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and Boc-protected amino group at the other, which can be deprotected with mildly acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. BocNH-PEG4-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC^? molecules) for targeted protein degradation

reaction suitability

reaction type: Pegylations
reagent type: cross-linking reagent

IC 50

Cleavable Linker; Alkyl/ether; PEGs

Boc-NH-PEG4-CH2COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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Boc-NH-PEG4-CH2COOH Suppliers

China 102 United States 8 Global 110

Xi‘an Deeptech Biotechnology Co.,LTD

Tel: +86-15114901355
Email: 15114901355@163.com
Country: China
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Yaopu(Shanghai) Pharmaceutical Technology Co., Ltd

Tel: 021-50929289 18616309303
Fax: -
Email: sales@ypptech.com.cn
Country: China
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Energy Chemical

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Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
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Chengdu Pukang Biotechnology Co., Ltd

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Fax: 086-28-82550468
Email: sales@pu-kang.com
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Bide Pharmatech Ltd.

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Email: product02@bidepharm.com
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
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Borenpharm Co., Ltd

Tel: 027-65563561
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Email: sales@borenpharm.com
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Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
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View Lastest Price from Boc-NH-PEG4-CH2COOH manufacturers

LAURENT

Product: BocNH-PEG4-CH2COOH 876345-13-0
Price: US $133.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 500kg
Release date: 2025-11-20

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: 2,2-dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azanonadecan-19-oic acid 876345-13-0
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2025-09-12

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Boc-NH-PEG4-CH2COOH 876345-13-0
Price: US $2.00-6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-08-06

876345-13-0, Boc-NH-PEG4-CH2COOHRelated Search:

Fmoc-amino-(PEG)n-acid Polyethylene Glycol Fmoc-NH-PEG6-CH2COOH O-[2-(Boc-amino)ethyl]-Oμ-(2-carboxyethyl)polyethylene glycol 3,000 Fmoc-NH-PEG12-CH2COOH Boc-NH-PEG4-CH2COOH

Boc-NH-PEG(3)-COOH

Boc-NH-PEG(3)-COOH(16atoMs)

Boc-NH-(PEG)4-CH2COOH

t-Boc-N-amido-PEG4-CH2CO2H

2,2-Dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azanonadecan-19-oic acid

5,8,11,14-Tetraoxa-2-azahexadecanedioic acid, 1-(1,1-dimethylethyl) ester

14-(Boc-amino)-3,6,9,12-tetraoxatetradecan-1-oic Acid

t-boc-N-amido-PEG4-acetic acid

NHBoc-PEG4-CH2COOH

BocNH-PEG4-CH2COOH/5,8,11,14-Tetraoxa-2-azahexadecanedioic acid, 1-(1,1-dimethylethyl) ester

Boc-NH-PEG-4-CH2COOH,PROTAC Linkers,BocNHPEG4CH2COOH,Inhibitor,inhibit,Antibody-drug conjugates linkers,ADC Linkers,Boc NH PEG4 CH2COOH

Boc-NH-PEG4-CH2CO0H

14-{[(tert-butoxy)carbonyl]amino}-3,6,9,12-tetraoxatetradecanoic acid

2-[2-[2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid

876345-13-0

C15H29NO8