Fmoc-NH-PEG6-CH2COOH
- Product Name
- Fmoc-NH-PEG6-CH2COOH
- CAS No.
- 437655-96-4
- Chemical Name
- Fmoc-NH-PEG6-CH2COOH
- Synonyms
- Fmoc-NH-PEG6-CH2COOH;Fmoc-PEG6-acetic acid;Fmoc-NH-PEG6-acetic Acid;5,8,11,14,17,20-Hexaoxa-2-azadocosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester;1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azatetracosan-24-oic acid;FmocNH-PEG6-CH2COOH/5,8,11,14,17,20-Hexaoxa-2-azadocosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
- CBNumber
- CB83340590
- Molecular Formula
- C29H39NO10
- Formula Weight
- 561.62
- MOL File
- 437655-96-4.mol
Fmoc-NH-PEG6-CH2COOH Property
- storage temp.
- 2-8°C
- form
- Viscous Liquid
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- BP-23534
- Product name
- Fmoc-NH-PEG6-CH2COOH
- Purity
- 95%
- Packaging
- 500mg
- Price
- $260
- Updated
- 2021/12/16
- Product number
- AS104018
- Product name
- FmocNH-PEG6-CH2COOH
- Purity
- 95+%
- Packaging
- 1g
- Price
- $532
- Updated
- 2021/12/16
- Product number
- A761108
- Product name
- FMoc-nh-peg6-ch2cooh
- Purity
- 95%
- Packaging
- 100mg
- Price
- $77
- Updated
- 2021/12/16
- Product number
- A761108
- Product name
- FMoc-nh-peg6-ch2cooh
- Purity
- 95%
- Packaging
- 250mg
- Price
- $145
- Updated
- 2021/12/16
- Product number
- B-0884
- Product name
- FmocNH-PEG6-CH2COOH
- Purity
- 97%
- Packaging
- 0.25g
- Price
- $168.66
- Updated
- 2021/12/16
Fmoc-NH-PEG6-CH2COOH Chemical Properties,Usage,Production
Description
Fmoc-NH-PEG6-CH2COOH is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG6-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
Cleavable Linker; Alkyl/ether; PEGs
References
[1] Michael A, et al. Synthesis of Bifunctional Integrin‐Binding Peptides Containing PEG Spacers of Defined Length for Non‐Viral Gene Delivery. Volume2008, Issue17.
Fmoc-NH-PEG6-CH2COOH Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Fmoc-NH-PEG6-CH2COOH manufacturers
- Product
- Fmoc-NH-PEG6-CH2COOH 437655-96-4
- Price
- US $925.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 300kg
- Release date
- 2025-11-24
- Product
- 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azatetracosan-24-oic acid 437655-96-4
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-12