Fmoc-N-amido-PEG1-acid
- Product Name
- Fmoc-N-amido-PEG1-acid
- CAS No.
- 1654740-73-4
- Chemical Name
- Fmoc-N-amido-PEG1-acid
- Synonyms
- 3-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethoxy)propanoic acid;Fmoc-NH-PEG1-COOH;FMoc-NH-PEG1-CH2CH2COOH;Fmoc-6-Amino-4-oxahexanoic acid;Fmoc-AEP;Fmoc-NH-PEG1-C2-acid;Fmoc-PEG1- CH2CH2COOH;Fmoc-N-amido-PEG1-acid;Fmoc-PEG1-propionic acid;Fmoc-NH-PEG1-Propanoic acid
- CBNumber
- CB92476057
- Molecular Formula
- C20H21NO5
- Formula Weight
- 355.38
- MOL File
- 1654740-73-4.mol
Fmoc-N-amido-PEG1-acid Property
- Boiling point:
- 589.9±40.0 °C(Predicted)
- Density
- 1.261±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 4.29±0.10(Predicted)
- form
- Solid
- color
- White to off-white
Safety
- HS Code
- 2924297099
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 280106
- Product name
- Fmoc-NH-PEG1-CH2CH2COOH
- Packaging
- 1g
- Price
- $150
- Updated
- 2021/12/16
- Product number
- 280106
- Product name
- Fmoc-NH-PEG1-CH2CH2COOH
- Packaging
- 5g
- Price
- $450
- Updated
- 2021/12/16
- Product number
- 6710DN
- Product name
- 3-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethoxy)propanoicacid
- Packaging
- 5g
- Price
- $505
- Updated
- 2021/12/16
- Product number
- BP-21988
- Product name
- Fmoc-N-amido-PEG1-acid
- Purity
- 98%
- Packaging
- 5G
- Price
- $680
- Updated
- 2021/12/16
- Product number
- CM250116
- Product name
- 3-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethoxy)propanoicacid
- Purity
- 95+%
- Packaging
- 5g
- Price
- $1141
- Updated
- 2021/12/16
Fmoc-N-amido-PEG1-acid Chemical Properties,Usage,Production
Description
Fmoc-N-amido-PEG1-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Fmoc-NH-PEG1-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Fmoc-N-amido-PEG1-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Fmoc-N-amido-PEG1-acid Suppliers
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View Lastest Price from Fmoc-N-amido-PEG1-acid manufacturers
- Product
- Fmoc-NH-PEG1-CH2CH2COOH 1654740-73-4
- Price
- US $56.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 300kg
- Release date
- 2025-11-18
- Product
- Fmoc-N-amido-PEG1-acid 1654740-73-4
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 25g
- Release date
- 2024-03-25
- Product
- Fmoc-N-amido-PEG1-acid 1654740-73-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-09