ChemicalBook > CAS DataBase List > Fmoc-N-amido-PEG1-acid

Fmoc-N-amido-PEG1-acid

Product Name
Fmoc-N-amido-PEG1-acid
CAS No.
1654740-73-4
Chemical Name
Fmoc-N-amido-PEG1-acid
Synonyms
3-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethoxy)propanoic acid;Fmoc-NH-PEG1-COOH;FMoc-NH-PEG1-CH2CH2COOH;Fmoc-6-Amino-4-oxahexanoic acid;Fmoc-AEP;Fmoc-NH-PEG1-C2-acid;Fmoc-PEG1- CH2CH2COOH;Fmoc-N-amido-PEG1-acid;Fmoc-PEG1-propionic acid;Fmoc-NH-PEG1-Propanoic acid
CBNumber
CB92476057
Molecular Formula
C20H21NO5
Formula Weight
355.38
MOL File
1654740-73-4.mol
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Fmoc-N-amido-PEG1-acid Property

Boiling point:
589.9±40.0 °C(Predicted)
Density 
1.261±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
4.29±0.10(Predicted)
form 
Solid
color 
White to off-white
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Safety

HS Code 
2924297099
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemPep
Product number
280106
Product name
Fmoc-NH-PEG1-CH2CH2COOH
Packaging
1g
Price
$150
Updated
2021/12/16
ChemPep
Product number
280106
Product name
Fmoc-NH-PEG1-CH2CH2COOH
Packaging
5g
Price
$450
Updated
2021/12/16
AK Scientific
Product number
6710DN
Product name
3-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethoxy)propanoicacid
Packaging
5g
Price
$505
Updated
2021/12/16
BroadPharm
Product number
BP-21988
Product name
Fmoc-N-amido-PEG1-acid
Purity
98%
Packaging
5G
Price
$680
Updated
2021/12/16
Chemenu
Product number
CM250116
Product name
3-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethoxy)propanoicacid
Purity
95+%
Packaging
5g
Price
$1141
Updated
2021/12/16
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Fmoc-N-amido-PEG1-acid Chemical Properties,Usage,Production

Description

Fmoc-N-amido-PEG1-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Fmoc-NH-PEG1-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Fmoc-N-amido-PEG1-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Fmoc-N-amido-PEG1-acid Suppliers

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View Lastest Price from Fmoc-N-amido-PEG1-acid manufacturers

LAURENT
Product
Fmoc-NH-PEG1-CH2CH2COOH 1654740-73-4
Price
US $56.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2025-11-18
Xian confluore Biological Technology Co., Ltd.
Product
Fmoc-N-amido-PEG1-acid 1654740-73-4
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
25g
Release date
2024-03-25
Career Henan Chemical Co
Product
Fmoc-N-amido-PEG1-acid 1654740-73-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2020-01-09

1654740-73-4, Fmoc-N-amido-PEG1-acidRelated Search:

Fmoc-AEEA-AEEA FMoc-NH-PEG7-CH2CH2COOH Fmoc-PEG4-NHS ester FMOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID 5,8,11,14-Tetraoxa-2-azahexadecanedioic acid FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Fmoc-NH-PEG3-CH2COOH 5-(9-FLUORENYLMETHYLOXYCARBONYL-AMINO)-3-OXAPENTANOIC ACID Fmoc-9-Amino-4,7-Dioxanonanoic acid 2,2-DIMETHYL-4-OXO-3,8,11,14-TETRAOXA-5-AZAHEXADECAN-16-OIC ACID 5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid,1-(9-fluren-9-ylmethyl)ester FMOC-18-AMINO-4,7,10,13,16-PENTAOXAOCTADECANOIC ACID BOC-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA FMoc-NH-PEG9-CH2CH2COOH FMoc-NH-PEG12-CH2CH2COOH Fmoc-NH-PEG6-CH2COOH FMoc-Val-Cit-PAB-PNP FMoc-NH-PEG10-CH2CH2COOH

  • Fmoc-6-Amino-4-oxahexanoic acid
  • FMoc-NH-PEG1-CH2CH2COOH
  • 3-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethoxy)propanoic acid
  • Fmoc-N-amido-PEG1-acid
  • Fmoc-PEG1-propionic acid
  • Fmoc-AEP
  • 3-[2-(Fmoc-amino)ethoxy]propanoic acid
  • 6-(Fmoc-amino)-4-oxahexanoic Acid
  • Fmoc-PEG1- CH2CH2COOH
  • Fmoc-NH-PEG1-C2-acid
  • Propanoic acid, 3-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethoxy]-
  • Fmoc-NH-PEG1-COOH
  • Fmoc-NH-PEG-Propionic Acid [165740-73-4]
  • Fmoc-NH-PEG1-Propanoic acid
  • 1654740-73-4
  • peg