ChemicalBook > CAS DataBase List > Fmoc-NH-PEG6-CH2COOH

Fmoc-NH-PEG6-CH2COOH

Product Name
Fmoc-NH-PEG6-CH2COOH
CAS No.
437655-96-4
Chemical Name
Fmoc-NH-PEG6-CH2COOH
Synonyms
Fmoc-NH-PEG6-CH2COOH;Fmoc-PEG6-acetic acid;Fmoc-NH-PEG6-acetic Acid;5,8,11,14,17,20-Hexaoxa-2-azadocosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester;1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azatetracosan-24-oic acid;FmocNH-PEG6-CH2COOH/5,8,11,14,17,20-Hexaoxa-2-azadocosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
CBNumber
CB83340590
Molecular Formula
C29H39NO10
Formula Weight
561.62
MOL File
437655-96-4.mol
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Fmoc-NH-PEG6-CH2COOH Property

storage temp. 
2-8°C
form 
Viscous Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23534
Product name
Fmoc-NH-PEG6-CH2COOH
Purity
95%
Packaging
500mg
Price
$260
Updated
2021/12/16
Activate Scientific
Product number
AS104018
Product name
FmocNH-PEG6-CH2COOH
Purity
95+%
Packaging
1g
Price
$532
Updated
2021/12/16
Ambeed
Product number
A761108
Product name
FMoc-nh-peg6-ch2cooh
Purity
95%
Packaging
100mg
Price
$77
Updated
2021/12/16
Ambeed
Product number
A761108
Product name
FMoc-nh-peg6-ch2cooh
Purity
95%
Packaging
250mg
Price
$145
Updated
2021/12/16
Acrotein
Product number
B-0884
Product name
FmocNH-PEG6-CH2COOH
Purity
97%
Packaging
0.25g
Price
$168.66
Updated
2021/12/16
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Fmoc-NH-PEG6-CH2COOH Chemical Properties,Usage,Production

Description

Fmoc-NH-PEG6-CH2COOH is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG6-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

Cleavable Linker; Alkyl/ether; PEGs

References

[1] Michael A, et al. Synthesis of Bifunctional Integrin‐Binding Peptides Containing PEG Spacers of Defined Length for Non‐Viral Gene Delivery. Volume2008, Issue17.

Fmoc-NH-PEG6-CH2COOH Preparation Products And Raw materials

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Preparation Products

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View Lastest Price from Fmoc-NH-PEG6-CH2COOH manufacturers

LAURENT
Product
Fmoc-NH-PEG6-CH2COOH 437655-96-4
Price
US $925.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2025-11-24
XIAMEN SINOPEG BIOTECH CO., LTD.
Product
1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azatetracosan-24-oic acid 437655-96-4
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2025-09-12

437655-96-4, Fmoc-NH-PEG6-CH2COOHRelated Search:

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  • Fmoc-NH-PEG6-CH2COOH
  • 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azatetracosan-24-oic acid
  • 5,8,11,14,17,20-Hexaoxa-2-azadocosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
  • Fmoc-PEG6-acetic acid
  • FmocNH-PEG6-CH2COOH/5,8,11,14,17,20-Hexaoxa-2-azadocosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
  • Fmoc-NH-PEG6-acetic Acid
  • 437655-96-4
  • C29H39NO10