4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline
- Product Name
- 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline
- CAS No.
- 190728-25-7
- Chemical Name
- 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline
- Synonyms
- Benzenam;4-(6,7-Dimethoxy-quinoL;Cabozantinib Amine Analog;Intermediate 1 of Cabozantinib;Cabozantinib Genotoxic Impurity I;4-[(6,7-dimethoxy-4-quinolinyl)oxy]-;4-(6,7-dimethoxy quinolinoxy) aniline;4-[(6,7-Dimethoxy-4-quinolyl)oxy]aniline;6,7-Dimethoxy-4-(4-aminophenoxy)quinoline;4-(4-Aminophenoxy)-6,7-dimethoxyquinoline
- CBNumber
- CB52652846
- Molecular Formula
- C17H16N2O3
- Formula Weight
- 296.32
- MOL File
- 190728-25-7.mol
4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Property
- Melting point:
- 211.0 to 215.0 °C
- Boiling point:
- 481.8±45.0 °C(Predicted)
- Density
- 1.246±0.06 g/cm3 (20 ºC 760 Torr)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly, Sonicated), Methanol (Slightly)
- form
- powder to crystal
- pka
- 6.79±0.30(Predicted)
- color
- Light yellow to Brown
- InChI
- InChI=1S/C17H16N2O3/c1-20-16-9-13-14(10-17(16)21-2)19-8-7-15(13)22-12-5-3-11(18)4-6-12/h3-10H,18H2,1-2H3
- InChIKey
- VXEQRXJATQUJSN-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=C(OC2C3C(N=CC=2)=CC(OC)=C(OC)C=3)C=C1
Safety
- HS Code
- 2933.49.7000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- D5070
- Product name
- 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline
- Packaging
- 200mg
- Price
- $155
- Updated
- 2024/03/01
- Product number
- D5070
- Product name
- 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline
- Packaging
- 1g
- Price
- $460
- Updated
- 2024/03/01
- Product number
- 43936
- Product name
- 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline,≥98%(HPLC)
- Purity
- ≥98%(HPLC)
- Packaging
- 1G
- Price
- $540.8
- Updated
- 2021/12/16
- Product number
- J90694
- Product name
- 4-(6,7-Dimethoxy-quinolin-4-yloxy)-phenylamine
- Packaging
- 1g
- Price
- $20
- Updated
- 2021/12/16
- Product number
- A138452
- Product name
- 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline
- Purity
- 97%
- Packaging
- 5g
- Price
- $54
- Updated
- 2021/12/16
4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Chemical Properties,Usage,Production
Uses
4-(6,7-Dimethoxy-Quinolin-4-Yloxy)-Phenylamine is used in preparation of Cabozantinib Defluorination impurity.
Chemical Reactivity
4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline is a primary alcohol that has been shown to catalyze the reaction of potassium carbonate with an alkali metal hydroxide to produce potassium. It has also been shown to be a base catalyst for the reaction of cyclopropanecarboxylic acid with an alcohol ester to produce high yield.
4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Preparation Products And Raw materials
Raw materials
Preparation Products
4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
View Lastest Price from 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline manufacturers
- Product
- 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline 190728-25-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1 ton
- Release date
- 2023-12-26
- Product
- 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline 190728-25-7
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30
- Product
- BenzenaMine, 4-[(6,7-diMethoxy-4-quinolinyl)oxy]- 190728-25-7
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98.0%min
- Supply Ability
- 100kg
- Release date
- 2023-03-11