4-PIPERIDIN-1-YL-BENZALDEHYDE
- Product Name
- 4-PIPERIDIN-1-YL-BENZALDEHYDE
- CAS No.
- 10338-57-5
- Chemical Name
- 4-PIPERIDIN-1-YL-BENZALDEHYDE
- Synonyms
- AKOS BC-2977;TIMTEC-BB SBB010803;IFLAB-BB F1274-0230;4-PIPERIDINOBENZALDEHYDE;4-(1-Piperidyl)benzaldehyde;1-(4-Formylphenyl)piperidine;4-PIPERIDIN-1-YL-BENZALDEHYDE;4-(1-Piperidinyl)benzaldehyde;4-PIPERIDINOBENZENECARBALDEHYDE;4-Piperidin-1-ylbenzaldehyde 95%
- CBNumber
- CB5267787
- Molecular Formula
- C12H15NO
- Formula Weight
- 189.25
- MOL File
- 10338-57-5.mol
4-PIPERIDIN-1-YL-BENZALDEHYDE Property
- Melting point:
- 61-64 °C
- Boiling point:
- 344.3±25.0 °C(Predicted)
- Density
- 1.091±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 3.88±0.20(Predicted)
- form
- solid
- color
- Yellow
- InChIKey
- ILJVPSVCFVQUAD-UHFFFAOYSA-N
- CAS DataBase Reference
- 10338-57-5(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 678953
- Product name
- 4-(1-Piperidinyl)benzaldehyde
- Purity
- 97%
- Packaging
- 5g
- Price
- $95
- Updated
- 2025/07/31
- Product number
- P3209
- Product name
- 4-(Piperidin-1-yl)benzaldehyde
- Purity
- min. 98.0 %
- Packaging
- 1G
- Price
- $49
- Updated
- 2025/07/31
- Product number
- P3209
- Product name
- 4-(Piperidin-1-yl)benzaldehyde
- Purity
- min. 98.0 %
- Packaging
- 5G
- Price
- $147
- Updated
- 2025/07/31
- Product number
- P991673
- Product name
- 4-(Piperidin-1-yl)benzaldehyde
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- OR1646
- Product name
- 4-(Piperidin-1-yl)benzaldehyde
- Purity
- 95%
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
4-PIPERIDIN-1-YL-BENZALDEHYDE Chemical Properties,Usage,Production
Uses
Reactant for synthesis of:
- Anti-inflammatory agents
- Piperidine incorporated α-aminophosphonates for antibacterial agents
- 5-Hydroxyaurone derivatives as growth inhibitors against HUVEC and some cancer cell lines
- NR2B selective NMDA receptor antagonists
- Fulleropyrrolidines
- Fluorophores for monitoring polymerization processes
Synthesis
110-89-4
459-57-4
10338-57-5
General procedure for the synthesis of 4-piperidin-1-yl-benzaldehyde from hexahydropyridine and p-fluorobenzaldehyde: A mixture of p-fluorobenzaldehyde (25.0 g, 0.200 mol), hexahydropyridine (0.300 mol), and anhydrous potassium carbonate (40.0 g) was mixed in DMF (300 mL) and a catalytic amount of Aliquat 336 reagent was added. The reaction mixture was refluxed at 100 °C for 24 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure and cooled to room temperature. Subsequently, the mixture was poured into ice water and allowed to stand overnight. The solid product formed was filtered, washed with water and recrystallized with methanol to afford the target compound 4-(piperidin-1-yl)benzaldehyde. The compound was obtained in 98% yield as yellow crystals with a melting point of 64°C, which is in agreement with literature reports [47,48].
References
[1] Bioorganic Chemistry, 2014, vol. 57, p. 65 - 82
[2] Russian Journal of General Chemistry, 2013, vol. 83, # 10, p. 1864 - 1868
[3] Zh. Obshch. Khim., 2013, vol. 83, # 10, p. 1654 - 1659,6
[4] Oriental Journal of Chemistry, 2013, vol. 29, # 4, p. 1531 - 1534
[5] European Journal of Organic Chemistry, 2017, vol. 2017, # 35, p. 5219 - 5224
4-PIPERIDIN-1-YL-BENZALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-PIPERIDIN-1-YL-BENZALDEHYDE manufacturers
- Product
- 4-PIPERIDIN-1-YL-BENZALDEHYDE 10338-57-5
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 97%-99%
- Supply Ability
- as request
- Release date
- 2018-12-23