ChemicalBook > CAS DataBase List > 4-PIPERIDIN-1-YL-BENZALDEHYDE

4-PIPERIDIN-1-YL-BENZALDEHYDE

Product Name
4-PIPERIDIN-1-YL-BENZALDEHYDE
CAS No.
10338-57-5
Chemical Name
4-PIPERIDIN-1-YL-BENZALDEHYDE
Synonyms
AKOS BC-2977;TIMTEC-BB SBB010803;IFLAB-BB F1274-0230;4-PIPERIDINOBENZALDEHYDE;4-(1-Piperidyl)benzaldehyde;1-(4-Formylphenyl)piperidine;4-PIPERIDIN-1-YL-BENZALDEHYDE;4-(1-Piperidinyl)benzaldehyde;4-PIPERIDINOBENZENECARBALDEHYDE;4-Piperidin-1-ylbenzaldehyde 95%
CBNumber
CB5267787
Molecular Formula
C12H15NO
Formula Weight
189.25
MOL File
10338-57-5.mol
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4-PIPERIDIN-1-YL-BENZALDEHYDE Property

Melting point:
61-64 °C
Boiling point:
344.3±25.0 °C(Predicted)
Density 
1.091±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
3.88±0.20(Predicted)
form 
solid
color 
Yellow
InChIKey
ILJVPSVCFVQUAD-UHFFFAOYSA-N
CAS DataBase Reference
10338-57-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
678953
Product name
4-(1-Piperidinyl)benzaldehyde
Purity
97%
Packaging
5g
Price
$95
Updated
2025/07/31
TCI Chemical
Product number
P3209
Product name
4-(Piperidin-1-yl)benzaldehyde
Purity
min. 98.0 %
Packaging
1G
Price
$49
Updated
2025/07/31
TCI Chemical
Product number
P3209
Product name
4-(Piperidin-1-yl)benzaldehyde
Purity
min. 98.0 %
Packaging
5G
Price
$147
Updated
2025/07/31
TRC
Product number
P991673
Product name
4-(Piperidin-1-yl)benzaldehyde
Packaging
50mg
Price
$60
Updated
2021/12/16
Apolloscientific
Product number
OR1646
Product name
4-(Piperidin-1-yl)benzaldehyde
Purity
95%
Packaging
1g
Price
$15
Updated
2021/12/16
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4-PIPERIDIN-1-YL-BENZALDEHYDE Chemical Properties,Usage,Production

Uses

Reactant for synthesis of:

  • Anti-inflammatory agents
  • Piperidine incorporated α-aminophosphonates for antibacterial agents
  • 5-Hydroxyaurone derivatives as growth inhibitors against HUVEC and some cancer cell lines
  • NR2B selective NMDA receptor antagonists
  • Fulleropyrrolidines
  • Fluorophores for monitoring polymerization processes

Synthesis

110-89-4

459-57-4

10338-57-5

General procedure for the synthesis of 4-piperidin-1-yl-benzaldehyde from hexahydropyridine and p-fluorobenzaldehyde: A mixture of p-fluorobenzaldehyde (25.0 g, 0.200 mol), hexahydropyridine (0.300 mol), and anhydrous potassium carbonate (40.0 g) was mixed in DMF (300 mL) and a catalytic amount of Aliquat 336 reagent was added. The reaction mixture was refluxed at 100 °C for 24 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure and cooled to room temperature. Subsequently, the mixture was poured into ice water and allowed to stand overnight. The solid product formed was filtered, washed with water and recrystallized with methanol to afford the target compound 4-(piperidin-1-yl)benzaldehyde. The compound was obtained in 98% yield as yellow crystals with a melting point of 64°C, which is in agreement with literature reports [47,48].

References

[1] Bioorganic Chemistry, 2014, vol. 57, p. 65 - 82
[2] Russian Journal of General Chemistry, 2013, vol. 83, # 10, p. 1864 - 1868
[3] Zh. Obshch. Khim., 2013, vol. 83, # 10, p. 1654 - 1659,6
[4] Oriental Journal of Chemistry, 2013, vol. 29, # 4, p. 1531 - 1534
[5] European Journal of Organic Chemistry, 2017, vol. 2017, # 35, p. 5219 - 5224

4-PIPERIDIN-1-YL-BENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-PIPERIDIN-1-YL-BENZALDEHYDE Suppliers

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View Lastest Price from 4-PIPERIDIN-1-YL-BENZALDEHYDE manufacturers

Career Henan Chemical Co
Product
4-PIPERIDIN-1-YL-BENZALDEHYDE 10338-57-5
Price
US $1.00/kg
Min. Order
1kg
Purity
97%-99%
Supply Ability
as request
Release date
2018-12-23

10338-57-5, 4-PIPERIDIN-1-YL-BENZALDEHYDERelated Search:

Ipodate Sodium 4-PIPERIDIN-1-YL-BENZOIC ACID 4'-PIPERIDINOACETOPHENONE 4-PIPERIDIN-1-YL-BENZALDEHYDE 3-NITRO-4-PIPERIDINOBENZALDEHYDE 2-PIPERIDIN-1-YL-BENZALDEHYDE, 95+%,2-PIPERIDIN-1-YL-BENZALDEHYDE 1-(3-AMINO-4-PIPERIDINOPHENYL)-1-ETHANONE 1-(3-NITRO-4-PIPERIDINOPHENYL)-1-ETHANONE 3-NITRO-4-PIPERIDIN-1-YLBENZOIC ACID ETHYL 1-(4-ACETYL-2-NITROPHENYL)-4-PIPERIDINECARBOXYLATE 1-(4-ACETYLPHENYL)-4-PIPERIDINECARBOXYLIC ACID 2-CHLORO-4-PIPERIDIN-1-YL-BENZALDEHYDE 2-ETHOXY-4-PIPERIDIN-1-YL-BENZALDEHYDE 2-METHYL-4-PIPERIDIN-1-YL-BENZALDEHYDE 4-(3-METHYL-PIPERIDIN-1-YL)-BENZALDEHYDE 4-[4-(Hydroxymethyl)piperidin-1-yl]benzaldehyde 2-METHOXY-4-PIPERIDIN-1-YL-BENZALDEHYDE 1-[4-(4-([4-(4-METHOXYPHENYL)PIPERAZINO]CARBONYL)PIPERIDINO)PHENYL]-1-ETHANONE

  • TIMTEC-BB SBB010803
  • AKOS BC-2977
  • 4-PIPERIDINOBENZALDEHYDE
  • 4-PIPERIDINOBENZENECARBALDEHYDE
  • 4-PIPERIDIN-1-YL-BENZALDEHYDE
  • IFLAB-BB F1274-0230
  • 4-(1-PIPERIDINYL)BENZALDEHYDE, 97%
  • 4-Piperidin-1-ylbenzaldehyde 95%
  • 4-PIPERIDIN-1-YL-BENZALDEHYDE, 95+%
  • 1-(4-Formylphenyl)piperidine
  • 4-(1-Piperidinyl)benzaldehyde 97%
  • JR-8866, 4-(Piperidin-1-yl)benzaldehyde, 97%
  • Benzaldehyde, 4-(1-piperidinyl)-
  • 4-(1-Piperidyl)benzaldehyde
  • 4-(1-Piperidinyl)benzaldehyde
  • 10338-57-5
  • Heterocyclic Building Blocks
  • Building Blocks
  • Piperidines
  • API intermediates