AF12198

ChemicalBook > CAS DataBase List > AF12198

Product Name: AF12198
CAS No.: 185413-30-3
Chemical Name: AF12198
Synonyms: AF12198;AF12198（TFA）;Ac-FEWTPGWYQ（Aze）YALPL-NH2;AF12198, human type I interleukin receptor antagonist;AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-AZE-TYR-ALA-LEU-PRO-LEU-NH2;AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-L-AZETIDINE-2-CARBONYL-TYR-ALA-LEU-PRO-LEU-NH2;AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-L-AZETIDINE-2-CARBOXYLIC ACID-TYR-ALA-LEU-PRO-LEU-NH2;L-Leucinamide, N-acetyl-L-phenylalanyl-L-α-glutamyl-L-tryptophyl-L-threonyl-L-prolylglycyl-L-tryptophyl-L-tyrosyl-L-glutaminyl-(2S)-2-azetidinecarbonyl-L-tyrosyl-L-alanyl-L-leucyl-L-prolyl-
CBNumber: CB5268870
Molecular Formula: C96H123N19O22
Formula Weight: 1895.12
MOL File: 185413-30-3.mol

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AF12198 Property

Melting point:: >179°C (dec.)
Density: 1.353±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMSO (Slightly), Methanol (Slightly), Water (Very Slightly)
form: solid
pka: 4.44±0.10(Predicted)
color: White to Off-White

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 1793
Product name: AF12198
Packaging: 1
Price: $352
Updated: 2021/12/16

Usbiological

Product number: 254553
Product name: AF 12198
Packaging: 1mg
Price: $631
Updated: 2021/12/16

TRC

Product number: A355020
Product name: AF12198
Packaging: 25mg
Price: $1760
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 67690
Product name: AF12198
Packaging: 25mg
Price: $2320
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA109195
Product name: Ac-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2
Packaging: 500ug
Price: $775
Updated: 2021/12/16

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AF12198 Chemical Properties,Usage,Production

Uses

AF 12198 is a peptide that selectively binds Interleukin-1 (IL-1) receptor and blocks in vivo responses to IL-1 (1). The interleukin-1 receptor can activate the innate immune response by binding to cytokines (2). Dysregulation of cytokine production can lead to aberrant immune cells activation that could result in auto-inflammatory disorders.

storage

Store at -20°C

AF12198 Preparation Products And Raw materials

Raw materials

Preparation Products

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185413-30-3, AF12198Related Search:

AF12198 2-Azetidinemethanamine AZETIDINE-2-CARBOXAMIDE

AF12198

AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-AZE-TYR-ALA-LEU-PRO-LEU-NH2

AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-L-AZETIDINE-2-CARBONYL-TYR-ALA-LEU-PRO-LEU-NH2

AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-L-AZETIDINE-2-CARBOXYLIC ACID-TYR-ALA-LEU-PRO-LEU-NH2

L-Leucinamide, N-acetyl-L-phenylalanyl-L-α-glutamyl-L-tryptophyl-L-threonyl-L-prolylglycyl-L-tryptophyl-L-tyrosyl-L-glutaminyl-(2S)-2-azetidinecarbonyl-L-tyrosyl-L-alanyl-L-leucyl-L-prolyl-

Ac-FEWTPGWYQ（Aze）YALPL-NH2

AF12198（TFA）

AF12198, human type I interleukin receptor antagonist

185413-30-3

C96H123N19O22