ChemicalBook > CAS DataBase List > AF12198
AF12198
- Product Name
- AF12198
- CAS No.
- 185413-30-3
- Chemical Name
- AF12198
- Synonyms
- AF12198;AF12198（TFA）;Ac-FEWTPGWYQ（Aze）YALPL-NH2;AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-AZE-TYR-ALA-LEU-PRO-LEU-NH2;AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-L-AZETIDINE-2-CARBONYL-TYR-ALA-LEU-PRO-LEU-NH2;AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-L-AZETIDINE-2-CARBOXYLIC ACID-TYR-ALA-LEU-PRO-LEU-NH2;L-Leucinamide, N-acetyl-L-phenylalanyl-L-α-glutamyl-L-tryptophyl-L-threonyl-L-prolylglycyl-L-tryptophyl-L-tyrosyl-L-glutaminyl-(2S)-2-azetidinecarbonyl-L-tyrosyl-L-alanyl-L-leucyl-L-prolyl-
- CBNumber
- CB5268870
- Molecular Formula
- C96H123N19O22
- Formula Weight
- 1895.12
- MOL File
- 185413-30-3.mol
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AF12198 Property
- Melting point:
- >179°C (dec.)
- Density
- 1.353±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Very Slightly)
- form
- solid
- pka
- 4.44±0.10(Predicted)
- color
- White to Off-White
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Tocris
- Product number
- 1793
- Product name
- AF12198
- Packaging
- 1
- Price
- $352
- Updated
- 2021/12/16
Usbiological
- Product number
- 254553
- Product name
- AF 12198
- Packaging
- 1mg
- Price
- $631
- Updated
- 2021/12/16
TRC
- Product number
- A355020
- Product name
- AF12198
- Packaging
- 25mg
- Price
- $1760
- Updated
- 2021/12/16
Medical Isotopes, Inc.
- Product number
- 67690
- Product name
- AF12198
- Packaging
- 25mg
- Price
- $2320
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FA109195
- Product name
- Ac-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2
- Packaging
- 500ug
- Price
- $775
- Updated
- 2021/12/16
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AF12198 Chemical Properties,Usage,Production
Uses
AF 12198 is a peptide that selectively binds Interleukin-1 (IL-1) receptor and blocks in vivo responses to IL-1 (1). The interleukin-1 receptor can activate the innate immune response by binding to cytokines (2). Dysregulation of cytokine production can lead to aberrant immune cells activation that could result in auto-inflammatory disorders.
storage
Store at -20°C
AF12198 Preparation Products And Raw materials
Raw materials
Preparation Products
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