ChemicalBook > CAS DataBase List > (S)-4-HydroxyMethyl AMbrisentan

(S)-4-HydroxyMethyl AMbrisentan

Product Name
(S)-4-HydroxyMethyl AMbrisentan
CAS No.
1106685-66-8
Chemical Name
(S)-4-HydroxyMethyl AMbrisentan
Synonyms
PDUAYPFMBRYSNN-LJQANCHMSA-N;(S)-4-Hydroxymethyl Ambrisentan;Ambrisentan 4-Hydroxymethyl Analog;4-Hydroxy Methyl Ambrisentan（Ambrisentan Impurity 15）;(S)-2-((4-(Hydroxymethyl)-6-methylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid;Benzenepropanoic acid, α-[[4-(hydroxymethyl)-6-methyl-2-pyrimidinyl]oxy]-β-methoxy-β-phenyl-, (αS)-
CBNumber
CB52709894
Molecular Formula
C22H22N2O5
Formula Weight
394.43
MOL File
1106685-66-8.mol
More
Less

(S)-4-HydroxyMethyl AMbrisentan Property

Melting point:
>130oC (dec.)
Boiling point:
600.0±60.0 °C(Predicted)
Density 
1.291±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
1.74±0.10(Predicted)
form 
Solid
color 
White
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
H947760
Product name
(S)-4-HydroxymethylAmbrisentan
Packaging
1mg
Price
$150
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
51749
Product name
(S)-4-HydroxymethylAmbrisentan
Packaging
10mg
Price
$2200
Updated
2021/12/16
More
Less

(S)-4-HydroxyMethyl AMbrisentan Chemical Properties,Usage,Production

Uses

(S)-4-Hydroxymethyl Ambrisentan is a metabolite of Ambrisentan (A575860), a nonpeptide endothelin ETA receptor antagonist. Antihypertensive.

(S)-4-HydroxyMethyl AMbrisentan Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(S)-4-HydroxyMethyl AMbrisentan Suppliers

China 20 India 4 United States 1 Global 25
Pharma Affiliates
Tel
--
Fax
--
Email
@pharmaffiliates.com
Country
India
ProdList
6754
Advantage
58
SynZeal Research Pvt Ltd
Tel
--
Fax
--
Email
standards@synzeal.com
Country
India
ProdList
6514
Advantage
58
Pharmaffiliates Analytics and Synthetics P. Ltd
Tel
--
Fax
--
Email
mktg@pharmaffiliates.com
Country
India
ProdList
6739
Advantage
58

1106685-66-8, (S)-4-HydroxyMethyl AMbrisentanRelated Search:

rac AMbrisentan Methyl Ester (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester Benzenepropanoic acid,a-hydroxy-b-methoxy-b-phenyl-,(aS)- AMBRISENTAN rac-Ambrisentan-d5 rac 4-Hydroxymethyl Ambrisentan Ambrisentan (R)-AMbrisentan 4,6-Dimethyl-2-hydroxypyrimidine MATFPFPXUXCLHI-UHFFFAOYSA-N 2-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-3,3-diphenyl-2-propenoic Acid Ambrisentan Acyl Glucuronide (Mixture of Diastereomers) Ambrisentan N-Oxide Ambrisentan pyrimidine Ester Impurity Ambrisentan Hydroxy Acid Impurity (R-isomer) 4-Hydroxymethyl ambrisentan acyl beta-glucuronide 4-Hydroxy Methyl Ambrisentan-D3

  • PDUAYPFMBRYSNN-LJQANCHMSA-N
  • Ambrisentan 4-Hydroxymethyl Analog
  • Benzenepropanoic acid, α-[[4-(hydroxymethyl)-6-methyl-2-pyrimidinyl]oxy]-β-methoxy-β-phenyl-, (αS)-
  • (S)-2-((4-(Hydroxymethyl)-6-methylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid
  • 4-Hydroxy Methyl Ambrisentan（Ambrisentan Impurity 15）
  • (S)-4-Hydroxymethyl Ambrisentan
  • 1106685-66-8