RS-102895 hydrochloride

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RS-102895 hydrochloride

Product Name: RS-102895 hydrochloride
CAS No.: 1173022-16-6
Chemical Name: RS-102895 hydrochloride
Synonyms: 3-trihydroxybenzene;RS-102895;RS 102895;RS102895;1'-(4-(Trifluoromethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride;Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-, hydrochloride;Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-, hydrochloride (1:1)
CBNumber: CB52729375
Molecular Formula: C21H22ClF3N2O2
Formula Weight: 426.86
MOL File: 1173022-16-6.mol

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RS-102895 hydrochloride Property

storage temp.: Inert atmosphere,Room Temperature
solubility: DMF: 25 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH 7.2) (1:2): 0.3 mg/ml; Ethanol: 2 mg/ml
form: Powder
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 18207
Product name: RS 102895 (hydrochloride)
Purity: ≥98%
Packaging: 1mg
Price: $34
Updated: 2024/03/01

Cayman Chemical

Product number: 18207
Product name: RS 102895 (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $85
Updated: 2024/03/01

Cayman Chemical

Product number: 18207
Product name: RS 102895 (hydrochloride)
Purity: ≥98%
Packaging: 10mg
Price: $133
Updated: 2024/03/01

Cayman Chemical

Product number: 18207
Product name: RS 102895 (hydrochloride)
Purity: ≥98%
Packaging: 25mg
Price: $288
Updated: 2024/03/01

TRC

Product number: R701005
Product name: RS 102895 hydrochloride
Packaging: 10mg
Price: $145
Updated: 2021/12/16

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RS-102895 hydrochloride Chemical Properties,Usage,Production

Description

The chemokine CCL2, also known as monocyte chemotactic protein-1 (MCP-1), stimulates leukocyte chemotaxis to sites of inflammation via signaling through the MCP-1 receptor, CCR2. RS 102895 is a spiropiperidine compound that acts as a CCR2 antagonist (IC₅₀ = 0.36 μM). It inhibits the related CCR1 receptor with an IC₅₀ value of 17.8 μM and inhibits adrenergic α_1a, α_1d, and 5HT_1A receptors with IC₅₀ values of 0.13, 0.32, and 47 μM, respectively. RS 102895 prevents chemotaxis of THP-1 cells (IC₅₀ = 1.7 μM) when MCP-1 is presented as a chemoattractant.

Uses

RS 102895 Hydrochloride is used as a leukocyte infiltrate marker for rosacea diagnosis.

storage

Desiccate at RT

RS-102895 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from RS-102895 hydrochloride manufacturers

Career Henan Chemical Co

Product: RS-102895 hydrochloride 1173022-16-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kgs
Release date: 2020-02-18

1173022-16-6, RS-102895 hydrochlorideRelated Search:

Pyridine hydrochloride Aniline hydrochloride Trimethylamine hydrochloride Methylamine hydrochloride

Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-, hydrochloride

RS-102895;RS 102895;RS102895

Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-, hydrochloride (1:1)

3-trihydroxybenzene

1'-(4-(Trifluoromethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride

1173022-16-6