ChemicalBook > CAS DataBase List > ZLN-024 hydrochloride

ZLN-024 hydrochloride

Product Name
ZLN-024 hydrochloride
CAS No.
1883548-91-1
Chemical Name
ZLN-024 hydrochloride
Synonyms
ZLN024 hydrochloride;ZLN-024 hydrochloride;ZLN 024 hydrochloride, 10 mM in DMSO;Inhibitor,AMP-activated protein kinase,ZLN-024,ZLN 024 hydrochloride,inhibit,ZLN024,ZLN 024,AMPK
CBNumber
CB52729380
Molecular Formula
C13H14BrClN2OS
Formula Weight
361.68
MOL File
1883548-91-1.mol
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ZLN-024 hydrochloride Property

solubility 
Soluble to 100 mM in DMSO
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
257174
Product name
ZLN 024 hydrochloride
Packaging
10mg
Price
$403
Updated
2021/12/16
TRC
Product number
Z485970
Product name
ZLN024Hydrochloride
Packaging
250mg
Price
$1385
Updated
2021/12/16
ChemScene
Product number
CS-3463
Product name
ZLN024hydrochloride
Purity
98.54%
Packaging
50mg
Price
$540
Updated
2021/12/16
ChemScene
Product number
CS-3463
Product name
ZLN024hydrochloride
Purity
98.54%
Packaging
5mg
Price
$78
Updated
2021/12/16
ChemScene
Product number
CS-3463
Product name
ZLN024hydrochloride
Purity
98.54%
Packaging
10mg
Price
$132
Updated
2021/12/16
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ZLN-024 hydrochloride Chemical Properties,Usage,Production

Uses

ZLN 024 Hydrochloride acts as an allosteric AMP-activated protein kinase activator, stimulating glucose uptake and fatty acid oxidation. Improved glucose tolerance and cholesterol content.

in vivo

C57BKS db/db mice are administered a 15 mg/kg/day dose of ZLN024 by daily gavage for 5 weeks; 250 mg/kg/day Metformin (Met) is used as a positive control. During the treatment period, there is no significant alteration in food intake and body weight compared with the vehicle group. After 4 weeks of treatment, ZLN024 improves glucose tolerance. ZLN024 reduces the fasting blood glucose by 15%. Liver tissue weight, triacylglycerol and the total cholesterol content are decreased[1].

IC 50

AMPK α2β2γ1: 0.13 μM (EC50); AMPK α1β1γ1: 0.42 μM (EC50); AMPK α2β1γ1: 0.95 μM (EC50)

storage

Store at +4°C

ZLN-024 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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ZLN-024 hydrochloride Suppliers

MedChemexpress LLC
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021-58955995
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609-228-5909
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sales@medchemexpress.cn
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United States
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TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
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32435
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TargetMol Chemicals Inc.
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+1-781-999-5354;
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support@targetmol.com
Country
United States
ProdList
39035
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United States Biological
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sales@advtechind.com
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United States
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United States Biological
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chemicals@usbio.net
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United States
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MedChemExpress
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Email
sales@medchemexpress.com
Country
United States
ProdList
6398
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1883548-91-1, ZLN-024 hydrochlorideRelated Search:


  • ZLN024 hydrochloride
  • ZLN-024 hydrochloride
  • Inhibitor,AMP-activated protein kinase,ZLN-024,ZLN 024 hydrochloride,inhibit,ZLN024,ZLN 024,AMPK
  • ZLN 024 hydrochloride, 10 mM in DMSO
  • 1883548-91-1
  • CHBrClNOS