ChemicalBook > CAS DataBase List > METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE

METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE

Product Name
METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE
CAS No.
10068-07-2
Chemical Name
METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE
Synonyms
METHYL 3-HYDROXYISOXAZOLE-5-CARBOXYLATE;3-ketoisoxazole-5-carboxylic acid methyl ester;methyl 3-oxo-2,3-dihydroisoxazole-5-carboxylate;EOS-61983;METHYL 3-OXOOXAZOLE-5-CARBOXYLATE;methyl 3-oxoisoxazole-5-carboxylate;methyl 3-oxo-1,2-oxazole-5-carboxylate;ETHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE;METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE;Methyl 3-hydroxy-isoxazol-5-carboxylate
CBNumber
CB5297302
Molecular Formula
C5H5NO4
Formula Weight
143.1
MOL File
10068-07-2.mol
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METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE Property

Melting point:
160-163 °C(lit.)
Boiling point:
261.15°C (rough estimate)
Density 
1.5918 (rough estimate)
refractive index 
1.5820 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform, Ethanol, Ether, Ethyl Acetate, Methanol
form 
Powder
pka
11.25±0.40(Predicted)
color 
Light Yellow
InChIKey
BBFWUUBQSXVHHZ-UHFFFAOYSA-N
CAS DataBase Reference
10068-07-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
338605
Product name
Methyl 3-hydroxy-5-isoxazolecarboxylate
Purity
98%
Packaging
1g
Price
$29
Updated
2023/01/07
Sigma-Aldrich
Product number
338605
Product name
Methyl 3-hydroxy-5-isoxazolecarboxylate
Purity
98%
Packaging
5g
Price
$88.2
Updated
2023/01/07
TCI Chemical
Product number
M2441
Product name
Methyl 3-Hydroxyisoxazole-5-carboxylate
Purity
>98.0%(GC)
Packaging
1g
Price
$50
Updated
2024/03/01
TCI Chemical
Product number
M2441
Product name
Methyl 3-Hydroxyisoxazole-5-carboxylate
Purity
>98.0%(GC)
Packaging
5g
Price
$165
Updated
2024/03/01
TRC
Product number
M312700
Product name
Methyl 3-Hydroxyisoxazole-5-carboxylate
Packaging
50g
Price
$1360
Updated
2021/12/16
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METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE Chemical Properties,Usage,Production

Chemical Properties

Light Yellow Powder

Uses

An interesting intermediate

Uses

Methyl 3-hydroxy-5-isoxazolecarboxylate was used in the enantioselective synthesis of a key precursor to the tetracycline antibiotics. It was also used in the preparation of formamidinopiperidine analog, an N-amidinopiperidine compound.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 20, p. 965, 1977 DOI: 10.1021/jm00217a023

METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE Suppliers

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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China
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PharmaBlock Sciences (Nanjing),Inc.
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86-025-86918232
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sales@pharmablock.com
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3B Pharmachem (Wuhan) International Co.,Ltd.
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
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Sales-CN@TCIchemicals.com
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BeiJing Hwrk Chemicals Limted
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Wuhan Chemwish Technology Co., Ltd
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Beijing Ouhe Technology Co., Ltd
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+86-10-82967029
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JinYan Chemicals(ShangHai) Co.,Ltd.
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86-021-50426522,50426273
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China
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View Lastest Price from METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE 10068-07-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE 10068-07-2
Price
US $1.00/KG
Min. Order
1KG
Purity
95%-99.99%
Supply Ability
1kg-10MT
Release date
2019-05-24

10068-07-2, METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATERelated Search:


  • 3-HYDROXYISOXAZOLE-5-CARBOXYLIC ACID*MET HYL ESTER
  • METHYL 3-OXOOXAZOLE-5-CARBOXYLATE
  • METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE
  • METHYL 3-HYDROXYISOXAZOLE-5-CARBOXYLATE
  • METHYL 3-HYDROXYL-5-ISOXAZOLECARBOXYLATE
  • Methyl 3-hydroxyisoxazole-5-carboxylate,99%
  • Methyl 3-hydroxy-1,2-oxazole-5-carboxylate
  • 2,3-DIHYDRO-3-OXO-5-ISOXAZOLECARBOXYLIC ACID, METHYL ESTER
  • Methyl 3-hydroxyisoxazole-5-carboxylate, 95+%
  • 3-ketoisoxazole-5-carboxylic acid methyl ester
  • 3-oxo-5-isoxazolecarboxylic acid methyl ester
  • methyl 3-oxo-1,2-oxazole-5-carboxylate
  • methyl 3-oxoisoxazole-5-carboxylate
  • methyl 3-oxo-2,3-dihydroisoxazole-5-carboxylate
  • 5-Isoxazolecarboxylic acid, 2,3-dihydro-3-oxo-, methyl ester
  • EOS-61983
  • ETHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE
  • Methyl 3-Hydroxyisoxazole-5-Carboxylate(WXC00884)
  • Methyl3-Hydroxyisoxazole-5-carboxylate&gt
  • Methyl 3-hydroxy-isoxazol-5-carboxylate
  • 10068-07-2
  • Building Blocks
  • Isoxazoles
  • Heterocyclic Building Blocks
  • Heterocyclic Compounds
  • Aromatics Compounds
  • Aromatics
  • Intermediates
  • Building Blocks
  • Heterocyclic Building Blocks
  • Isoxazoles
  • pharmacetical
  • Heterocycles series