ChemicalBook > CAS DataBase List > RSV604
RSV604
- Product Name
- RSV604
- CAS No.
- 676128-63-5
- Chemical Name
- RSV604
- Synonyms
- RSV604;CS-2092;RSV604;RSV 604;Urea, N-[(3S)-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-N'-(2-fluorophenyl)-;(S)-1-(2-fluoro-phenyl)-3-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-urea;virus,Respiratory syncytial virus,A 60444,respiratory,protein,inhibit,RSV,syncytial,A-60444,Inhibitor,A60444,RSV604,RSV 604,nucleocapsid,RSV-604
- CBNumber
- CB53041458
- Molecular Formula
- C22H17FN4O2
- Formula Weight
- 388.39
- MOL File
- 676128-63-5.mol
More
Less
RSV604 Property
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:20): 0.04 mg/ml; DMSO: 20 mg/ml; Ethanol: 5 mg/ml
- form
- A solid
More
Less
N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 29041
- Product name
- RSV-604
- Packaging
- 5mg
- Price
- $100
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 29041
- Product name
- RSV-604
- Packaging
- 25mg
- Price
- $381
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 29041
- Product name
- RSV-604
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 29041
- Product name
- RSV-604
- Packaging
- 10mg
- Price
- $184
- Updated
- 2024/03/01
AK Scientific
- Product number
- 8549CN
- Product name
- 1-(2-Fluorophenyl)-3-[(3S)-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepin-3-yl]urea
- Packaging
- 5mg
- Price
- $209
- Updated
- 2021/12/16
More
Less
RSV604 Chemical Properties,Usage,Production
Biological Activity
RSV604 (A-60444), a novel benzodiazepine, is an inhibitor of respiratory syncytial virus (RSV) with EC50 of 0.86 μM. It has the potential to treat RSV-related diseases. Phase 2.
in vitro
RSV604 (5 days) inhibits the growth of four laboratory strains of RSV (RSS, Long, A2 and B), with EC 50 s ranging from 0.5 to 0.9 μM in plaque reduction assay.
It (6 days) inhibits RSV-induced HEp-2 cell death, with an EC 50 of 0.86 μM.
Also RSV604 (3 days) reduces viral antigen synthesis in RSV-infected HEp-2 cells, with an EC 50 of 1.7 μM.
RSV604 (1-20 μM; 7 days) dose-dependently inhibits RSV infection in human airway epithelial (HAE) cells, with no gross cytotoxicity, leakage of basolateral fluid to the apical surface, or alteration of cilium beat frequency.
target
| Target | Value |
| RSV (Cell-free assay) | 0.86 μM(EC50) |
RSV604 Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
RSV604 Suppliers
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 14059
- Advantage
- 65
- Tel
- 021-58950125
- Fax
- (86) 21-58955996
- info@chemexpress.com
- Country
- China
- ProdList
- 7553
- Advantage
- 61
- Tel
- 021-52996696，15000506266 15000506266
- Fax
- +86-21-52996696
- Country
- China
- ProdList
- 4153
- Advantage
- 55
- Tel
- 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 9926
- Advantage
- 65
- Tel
- 020-61288194 61288195
- Fax
- 020-61288700
- 505721671@qq.com
- Country
- China
- ProdList
- 3868
- Advantage
- 58
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 27322
- Advantage
- 60
- Tel
- 17754423994 17754423994
- Fax
- QQ:2853530913
- 2853530910@QQ.com
- Country
- China
- ProdList
- 8011
- Advantage
- 62
- Tel
- 21-31433387 15618786686
- Fax
- QQ:1369748377
- sales@rechemscience.com
- Country
- China
- ProdList
- 2992
- Advantage
- 58
- Tel
- QQ:65489617 15618227136
- Fax
- 21-5161 9052
- info@SuperLan-chem.com
- Country
- China
- ProdList
- 9756
- Advantage
- 58
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131981
- Advantage
- 58