Acetyl Hexapeptide-1
- Product Name
- Acetyl Hexapeptide-1
- CAS No.
- 448944-47-6
- Chemical Name
- Acetyl Hexapeptide-1
- Synonyms
- melitane;ACETYL HEXAPEPTIDE-1;melitane/acetylhexapeptide-1;peptides Acetyl Hexapeptide-1;Ac-Nle-Ala-His-D-Phe-Arg-Trp-NH2;Acetyl Hexapeptide-1 (Reference: Melitane);N-Acetyl-L-norleucyl-L-alanyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophanamide;L-Tryptophanamide, N-acetyl-L-norleucyl-L-alanyl-L-histidyl-D-phenylalanyl-L-arginyl-;N-Acetyl-L-norleucyl-L-alanyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophanamide USP/EP/BP;Glp-Gly-Cys-Cys-Asn-Gly-Pro-Lys-Gly-Cys-Ser-Ser-Lys-Trp-Cys-Arg-Asp-His-Ala-Arg-Cys-Cys-NH2（Cys3&Cya15，Cys4&Cys22，Cys10&Cys23）
- CBNumber
- CB53052034
- Molecular Formula
- C43H59N13O7
- Formula Weight
- 870.01
- MOL File
- 448944-47-6.mol
Acetyl Hexapeptide-1 Property
- Density
- 1.39±0.1 g/cm3(Predicted)
- pka
- 13.36±0.46(Predicted)
- Sequence
- Ac-{Nle}-Ala-His-{d-Phe}-Arg-Trp-NH2
- Cosmetics Ingredients Functions
- SKIN CONDITIONING
- InChIKey
- WPIQUSRULDNCKM-IFSWANACSA-N
- SMILES
- C(N)(=O)[C@H](CC1C2=C(C=CC=C2)NC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)[C@H](CC1N=CNC=1)NC(=O)[C@H](C)NC(=O)[C@H](CCCC)NC(C)=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Acetyl Hexapeptide-1 Chemical Properties,Usage,Production
Description
Acetyl hexapeptide-1 is a synthetic peptide composed of the amino acids alanine, arginine, histidine, leucine, phenylalanine and tryptophan. It helps skin better defend itself from environmental aggressors by virtue of a calming effect. This peptide can also help promote a visibly more even skin tone by playing a role in how melanin moves through skin.
Acetyl Hexapeptide-1 is a bit of a special snowflake among peptides as it's not a wrinkle-smoothing, anti-aging active like most of the other ones but it can stimulate pigmentation and melanin production (by interacting with a skin cell receptor called MC1R).
As melanin not only gives the skin its nice tanned color but also works as a natural protection factor, Acetyl Hexapeptide-1, aka Melitane does the same. It not only boosts a natural or an artificial tan but gives extra protection against UV-induced DNA and free radical damage and protects the skin against UV-caused redness.
Definition
Acetyl Hexapeptide-1 is the reaction product of Alanine, arginine, histidine, leucine, phenylalanine and tryptophane hexapeptide with acetic acid. It activates the regulation of melanin synthesis, relating the protection of natural light and inflammatory regulator.
Application
Acetyl Hexapeptide-1 works as a bio-α-MSH peptide analog. It stimulates hair pigmentation, darkens hair and reverses the gray hair process. It also can help repair DNA damage caused by UV exposure and reduce the skin erythema.
benefits
Acetyl Hexapeptide-1has affinity to MC1-R, which is a biomimeticpeptide simulating a-MSH, promote melaninproduction by combining with MC1-R,lt alsopromotes transfer melanin from melanocytes tokeratinocytes, coloring the hair.Its recommended dosage is 0.1~5%.
Mechanism of action
Acetyl Hexapeptide-1 is a novel acetyl hexapeptide, which mainly acts on a presynaptic membrane and a postsynaptic membrane to reduce the transmission of neurotransmitters and reduce the shrinkage of muscles, thereby achieving the purpose of smoothing expression lines and the addition of acetyl hexapeptide-1 to cosmetics does not cause the instability of the cosmetic properties.
Acetyl Hexapeptide-1 Preparation Products And Raw materials
Raw materials
Preparation Products
Acetyl Hexapeptide-1 Suppliers
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View Lastest Price from Acetyl Hexapeptide-1 manufacturers
- Product
- Acetyl Hexapeptide-1 448944-47-6
- Price
- US $500.00-500.00/kg
- Min. Order
- 1kg
- Purity
- ≥99.00%
- Supply Ability
- 1000000
- Release date
- 2025-10-10
- Product
- Acetyl Hexapeptide-1 448944-47-6
- Price
- US $2.00-5.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-07-08
- Product
- Acetyl Hexapeptide-1 448944-47-6
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 97%min HPLC
- Supply Ability
- 1000G
- Release date
- 2021-07-05