Benifits in Skin
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Tripeptide-10 citrulline

Benifits in Skin
Product Name
Tripeptide-10 citrulline
CAS No.
960531-53-7
Chemical Name
Tripeptide-10 citrulline
Synonyms
Trylagen;Decorinyl;Tripeptide-10 citrulline;Tripeptide-10 Citrullinepowder;Decorinyl/Tripeptide-10 citrulline;Tripeptide-10 Citrulline, decorinyl;L-Ornithinamide,L-lysyl-L-α-aspartyl-L-isoleucyl-N5-(aminocarbonyl)-;L-Ornithinamide, L-lysyl-L-α-aspartyl-L-isoleucyl-N5-(aminocarbonyl)-;L-Lysyl-L-alpha-aspartyl-L-isoleucyl-N5-(aminocarbonyl)-L-ornithinamide;(3S)-4-[[(2S,3S)-1-[[(2S)-1-amino-5-(carbamoylamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-[[(2S)-2,6-diaminohexanoyl]amino]-4-oxobutanoic acid
CBNumber
CB73052003
Molecular Formula
C22H42N8O7
Formula Weight
530.62
MOL File
960531-53-7.mol
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Tripeptide-10 citrulline Property

Boiling point:
965.2±65.0 °C(Predicted)
Density 
1.252±0.06 g/cm3(Predicted)
pka
4.15±0.10(Predicted)
InChIKey
UKVZHOYDLCJTIU-VPRSOUQONA-N
SMILES
C(NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)N)(=O)[C@H](CCCNC(N)=O)N |&1:4,5,12,20,28,r|
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Hazard and Precautionary Statements (GHS)

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Tripeptide-10 citrulline Chemical Properties,Usage,Production

Benifits in Skin

Tripeptide-10 Citrulline, or Decorinyl, is a tetrapeptide engineered in 2008 from decorin, whose peptide chain follows the +, –, 0, + charge pattern shown to be necessary for the binding of decorin to collagen. Not only does Tripeptide-10 Citrulline help regulate fibrillogenesis, it also regulates collagen fiber dimensions and uniformity, making this oligopeptide a good candidate for maintaining elasticity of skin and reducing wrinkles. A single-blinded parallel group controlled trial compared cream containing Tripeptide-10 Citrulline to placebo.

Description

Tripeptide-10 Citrulline (also known under the trade name Decorinyl?) is a brilliant new collagen organizing tetrapeptide that mimics decorin, improving collagen structures and restoring the skin's suppleness and resiliency. Thanks to decorin-like action, it regulates the fibrillogenesis process and collagen fibril dimensions.

Definition

Tripeptide-10 Citrulline is a new cosmetic active, designed as a substitute of decorin, that specifically targets collagen fibre organization to regulate collagen fibrillogenesis.

Biological Functions

Tripeptide-10 Citrulline ensures uniformity in fibril diameter and increases skin suppleness. Due to its good cohesion of collagen fibres, Tripeptide-10 Citrulline is widely used in anti-aging cosmetic products.

General Description

Citrulline is an organic compound and amino acid that is extracted from the skin of the watermelon, among other things. Like all amino acids it has water-binding properties and is therefore used in skin care cosmetics as moisturizer.

Mechanism of action

The aging process makes notable changes in the skin proteins. Decorin is an essential protein in the skin that controls collagen aggregation, equalizes fibril diameters, and maintains a normal packing. Unfortunately, the changes also affect decorin that becomes truncated and loses its effectiveness over time. This modified form (non-functional) of decorin, missing in young skin, lacks parts that can interact with collagen. As a result, it leaves a considerable negative effect on the skin's firmness and elasticity, resulting in morphologic changes in collagen organization in the mature skin.

Tripeptide-10 citrulline Preparation Products And Raw materials

Raw materials

Preparation Products

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Tripeptide-10 citrulline Suppliers

Chengdu Youngshe Chemical Co., Ltd.
Tel
028-62328193 17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
2353
Advantage
58
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Cellmano Biotech Limited
Tel
0551-65326643 18156095617
Fax
0551-65326641
Email
info@cellmano.com
Country
China
ProdList
1011
Advantage
55
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Creative Peptides
Tel
Email
info@creative-peptides.com
Country
United States
ProdList
6084
Advantage
56
Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 15618227136
Fax
21-5161 9052
Email
info@SuperLan-chem.com
Country
China
ProdList
9445
Advantage
58
Wuxi Asia Peptide Biotechnology Limited Company
Tel
0510-83583050 13771062561
Fax
0510-83583039
Email
willsun@peptide-search.com
Country
China
ProdList
6716
Advantage
58
Nanjing Leon Biological Technology Co., Ltd.
Tel
17705183659
Fax
84523390
Email
sales@njleonbiotech.com
Country
China
ProdList
5503
Advantage
55
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805 13082558573
Fax
025-58361106-806
Email
liugang@njpeptide.com
Country
China
ProdList
9961
Advantage
55
Shanghai Mokay Pharmaceutical Technology Co., Ltd.
Tel
021-60257269 18601606476
Fax
+86-21-60253672
Email
yl@mkpharma.cn
Country
China
ProdList
206
Advantage
58
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View Lastest Price from Tripeptide-10 citrulline manufacturers

Wuhan Haorong Biotechnology Co.,Ltd
Product
Tripeptide-10 citrulline 960531-53-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500
Release date
2023-08-18
zhuzhou dingcheng meihei comestic co.,ltd
Product
Tripeptide-10 citrulline 960531-53-7
Price
US $35.00/Box
Min. Order
1Box
Purity
99.99%
Supply Ability
10000000000
Release date
2023-12-19
Nantong Guangyuan Chemicl Co,Ltd
Product
Tripeptide-10 citrulline 960531-53-7
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2023-11-03

960531-53-7, Tripeptide-10 citrullineRelated Search:


  • L-Lysyl-L-alpha-aspartyl-L-isoleucyl-N5-(aminocarbonyl)-L-ornithinamide
  • Tripeptide-10 citrulline
  • Decorinyl/Tripeptide-10 citrulline
  • Trylagen
  • Tripeptide-10 Citrulline, decorinyl
  • Decorinyl
  • (3S)-4-[[(2S,3S)-1-[[(2S)-1-amino-5-(carbamoylamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-[[(2S)-2,6-diaminohexanoyl]amino]-4-oxobutanoic acid
  • L-Ornithinamide, L-lysyl-L-α-aspartyl-L-isoleucyl-N5-(aminocarbonyl)-
  • Tripeptide-10 Citrullinepowder
  • (3S)-4-[[(2S,3S)-1-[[(2SChemicalbook)-1-amino-5-(carbamoylamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-[[(2S)-2,6-diaminohexanoyl]amino]-4-oxobutanoicacid
  • L-Ornithinamide,L-lysyl-L-α-aspartyl-L-isoleucyl-N5-(aminocarbonyl)-
  • 960531-53-7
  • C22H42N8O7
  • APIs