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L-Malic acid

Product Name
L-Malic acid
CAS No.
97-67-6
Chemical Name
L-Malic acid
Synonyms
L-MALIC ACID;L-Malic;(2S)-2-hydroxybutanedioic acid;L-Mailcacid;HYDROXYBUTANEDIOIC ACID;L-Gydroxybutanedioicacid;pinguosuan;apple acid;(S)-(-)-MALIC ACID;-(-)-MaL
CBNumber
CB0493594
Molecular Formula
C4H6O5
Formula Weight
134.09
MOL File
97-67-6.mol
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L-Malic acid Property

Melting point:
101-103 °C (lit.)
alpha 
-2 º (c=8.5, H2O)
Boiling point:
167.16°C (rough estimate)
Density 
1.60
vapor pressure 
0Pa at 25℃
FEMA 
2655 | L-MALIC ACID
refractive index 
-6.5 ° (C=10, Acetone)
Flash point:
220 °C
storage temp. 
Store below +30°C.
solubility 
H2O: 0.5 M at 20 °C, clear, colorless
form 
Powder
color 
White
Specific Gravity
1.595 (20/4℃)
Odor
odorless
PH
2.2 (10g/l, H2O, 20℃)
pka
(1) 3.46, (2) 5.10(at 25℃)
Odor Type
odorless
optical activity
[α]20/D 30±2°, c = 5.5% in pyridine
Water Solubility 
soluble
Merck 
14,5707
JECFA Number
619
BRN 
1723541
InChIKey
BJEPYKJPYRNKOW-REOHCLBHSA-N
LogP
-1.68
CAS DataBase Reference
97-67-6(CAS DataBase Reference)
NIST Chemistry Reference
Butanedioic acid, hydroxy-, (s)-(97-67-6)
EPA Substance Registry System
Butanedioic acid, 2-hydroxy-, (2S)- (97-67-6)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
ON7175000
TSCA 
Yes
HS Code 
29181980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.00384
Product name
L-(-)-Malic acid
Purity
for resolution of racemates for synthesis
Packaging
5G
Price
$27.2
Updated
2024/03/01
Sigma-Aldrich
Product number
8.00384
Product name
L-(-)-Malic acid
Purity
for resolution of racemates for synthesis
Packaging
10g
Price
$39.7
Updated
2024/03/01
Sigma-Aldrich
Product number
8.00384
Product name
L-(-)-Malic acid
Purity
for resolution of racemates for synthesis
Packaging
50g
Price
$99.8
Updated
2024/03/01
Sigma-Aldrich
Product number
8.00384
Product name
L-(-)-Malic acid
Purity
for resolution of racemates for synthesis
Packaging
500g
Price
$411
Updated
2024/03/01
Sigma-Aldrich
Product number
8.00384
Product name
L-(-)-Malic acid
Purity
for resolution of racemates for synthesis
Packaging
1kg
Price
$801
Updated
2024/03/01
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L-Malic acid Chemical Properties,Usage,Production

Description

L-Malic acid is nearly odorless (sometimes a faint, acrid odor) with a tart, acidic taste. It is nonpungent. May be prepared by hydration of maleic acid; by fermentation from sugars.

Chemical Properties

L-Malic acid is nearly odorless (sometimes a faint, acrid odor). This compound has a tart, acidic, nonpungent taste.

Chemical Properties

clear colourless solution

Occurrence

Occurs in maple sap, apple, melon, papaya, beer, grape wine, cocoa, sake, kiwifruit and chicory root.

Uses

L-Malic acid is used as a food additive, Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B.

Uses

The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid rece

Uses

Intermediate in chemical synthesis. Chelating and buffering agent. Flavoring agent, flavor enhancer and acidulant in foods.

Preparation

L-Malic acid can be prepared by hydration of maleic acid; by fermentation from sugar.

Definition

ChEBI: An optically active form of malic acid having (S)-configuration.

General Description

L-Malic acid is an organic acid that is commonly found in wine. It plays an important role in wine microbiological stability.

Biochem/physiol Actions

L-Malic acid is a part of cellular metabolism. Its application is recognized in pharmaceutics. It is useful in the treatment of hepatic malfunctioning, effective against hyper-ammonemia. It is used as a part of amino acid infusion. L-Malic acid also serves as a nanomedicine in the treatment of brain neurological disorders. A TCA (Krebs cycle) intermediate and partner in the malic acid aspartate shuttle.

Purification Methods

Crystallise S-malic acid (charcoal) from ethyl acetate/pet ether (b 55-56o), keeping the temperature below 65o. Or dissolve it by refluxing in fifteen parts of anhydrous diethyl ether, decant, concentrate to one-third volume and crystallise it at 0o, repeatedly to constant melting point. [Beilstein 3 IV 1123.]

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L-Malic acid Suppliers

CHANGMAO BIOCHEMICAL ENGINEERING CO., LTD
Tel
86(519) 86850125
Email
15961234040@139.com
Country
CHINA
ProdList
1
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Jinan Daen Pharmaceutical Technology Co., Ltd
Tel
0531-68657833 15553112864
Fax
-
Email
2098511197@qq.com
Country
China
ProdList
219
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Changzhou Success Chemical Co., Ltd.
Tel
18961148122
Email
278954761@qq.com
Country
China
ProdList
24
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58
Shaanxi Fujuyuan Biotechnology Co., Ltd.
Tel
17319979867
Email
969147291@qq.com
Country
China
ProdList
65
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58
Shandong Yatu Biotechnology Co. LTD
Tel
0531-55555418 15301096991
Email
811301959@qq.com
Country
China
ProdList
565
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Shanghai Maclean Biochemical Technology Co., LTD
Tel
021-50706066 15221275939
Email
shenlinxing@macklin.cn
Country
China
ProdList
29803
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58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
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future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1998
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65
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View Lastest Price from L-Malic acid manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
L-Malic acid 97-67-6
Price
US $200.00-85.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-04-23
Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
L-Malic Acid 97-67-6
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000kg
Release date
2024-04-22
Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
L-Malic acid 97-67-6
Price
US $50.00/kg
Min. Order
1kg
Purity
99.10%
Supply Ability
5000kg
Release date
2024-04-18

97-67-6, L-Malic acidRelated Search:


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