L-Malic acid
- Product Name
- L-Malic acid
- CAS No.
- 97-67-6
- Chemical Name
- L-Malic acid
- Synonyms
- L-MALIC ACID;L-Malic;(2S)-2-hydroxybutanedioic acid;L-Mailcacid;HYDROXYBUTANEDIOIC ACID;L-Gydroxybutanedioicacid;pinguosuan;apple acid;(S)-(-)-MALIC ACID;-(-)-MaL
- CBNumber
- CB0493594
- Molecular Formula
- C4H6O5
- Formula Weight
- 134.09
- MOL File
- 97-67-6.mol
L-Malic acid Property
- Melting point:
- 101-103 °C (lit.)
- alpha
- -2 º (c=8.5, H2O)
- Boiling point:
- 167.16°C (rough estimate)
- Density
- 1.60
- vapor pressure
- 0Pa at 25℃
- FEMA
- 2655 | L-MALIC ACID
- refractive index
- -6.5 ° (C=10, Acetone)
- Flash point:
- 220 °C
- storage temp.
- Store below +30°C.
- solubility
- H2O: 0.5 M at 20 °C, clear, colorless
- form
- Powder
- color
- White
- Specific Gravity
- 1.595 (20/4℃)
- Odor
- odorless
- PH
- 2.2 (10g/l, H2O, 20℃)
- pka
- (1) 3.46, (2) 5.10(at 25℃)
- Odor Type
- odorless
- optical activity
- [α]20/D 30±2°, c = 5.5% in pyridine
- Water Solubility
- soluble
- Merck
- 14,5707
- JECFA Number
- 619
- BRN
- 1723541
- InChIKey
- BJEPYKJPYRNKOW-REOHCLBHSA-N
- LogP
- -1.68
- CAS DataBase Reference
- 97-67-6(CAS DataBase Reference)
- NIST Chemistry Reference
- Butanedioic acid, hydroxy-, (s)-(97-67-6)
- EPA Substance Registry System
- Butanedioic acid, 2-hydroxy-, (2S)- (97-67-6)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- RTECS
- ON7175000
- TSCA
- Yes
- HS Code
- 29181980
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 8.00384
- Product name
- L-(-)-Malic acid
- Purity
- for resolution of racemates for synthesis
- Packaging
- 5G
- Price
- $27.2
- Updated
- 2024/03/01
- Product number
- 8.00384
- Product name
- L-(-)-Malic acid
- Purity
- for resolution of racemates for synthesis
- Packaging
- 10g
- Price
- $39.7
- Updated
- 2024/03/01
- Product number
- 8.00384
- Product name
- L-(-)-Malic acid
- Purity
- for resolution of racemates for synthesis
- Packaging
- 50g
- Price
- $99.8
- Updated
- 2024/03/01
- Product number
- 8.00384
- Product name
- L-(-)-Malic acid
- Purity
- for resolution of racemates for synthesis
- Packaging
- 500g
- Price
- $411
- Updated
- 2024/03/01
- Product number
- 8.00384
- Product name
- L-(-)-Malic acid
- Purity
- for resolution of racemates for synthesis
- Packaging
- 1kg
- Price
- $801
- Updated
- 2024/03/01
L-Malic acid Chemical Properties,Usage,Production
Description
L-Malic acid is nearly odorless (sometimes a faint, acrid odor) with a tart, acidic taste. It is nonpungent. May be prepared by hydration of maleic acid; by fermentation from sugars.
Chemical Properties
L-Malic acid is nearly odorless (sometimes a faint, acrid odor). This compound has a tart, acidic, nonpungent taste.
Chemical Properties
clear colourless solution
Occurrence
Occurs in maple sap, apple, melon, papaya, beer, grape wine, cocoa, sake, kiwifruit and chicory root.
Uses
L-Malic acid is used as a food additive, Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B.
Uses
The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid rece
Uses
Intermediate in chemical synthesis. Chelating and buffering agent. Flavoring agent, flavor enhancer and acidulant in foods.
Preparation
L-Malic acid can be prepared by hydration of maleic acid; by fermentation from sugar.
Definition
ChEBI: An optically active form of malic acid having (S)-configuration.
General Description
L-Malic acid is an organic acid that is commonly found in wine. It plays an important role in wine microbiological stability.
Biochem/physiol Actions
L-Malic acid is a part of cellular metabolism. Its application is recognized in pharmaceutics. It is useful in the treatment of hepatic malfunctioning, effective against hyper-ammonemia. It is used as a part of amino acid infusion. L-Malic acid also serves as a nanomedicine in the treatment of brain neurological disorders. A TCA (Krebs cycle) intermediate and partner in the malic acid aspartate shuttle.
Purification Methods
Crystallise S-malic acid (charcoal) from ethyl acetate/pet ether (b 55-56o), keeping the temperature below 65o. Or dissolve it by refluxing in fifteen parts of anhydrous diethyl ether, decant, concentrate to one-third volume and crystallise it at 0o, repeatedly to constant melting point. [Beilstein 3 IV 1123.]
L-Malic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from L-Malic acid manufacturers
- Product
- L(-)-Malic acid 97-67-6
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-08-01
- Product
- L-Malic acid 97-67-6
- Price
- US $200.00-85.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-04-23
- Product
- L-(-)-Malic acid 97-67-6
- Price
- US $60.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-05-11