4-(4-FLUORO-PHENYL)-PIPERIDINE

Product Name: 4-(4-FLUORO-PHENYL)-PIPERIDINE
CAS No.: 37656-48-7
Chemical Name: 4-(4-FLUORO-PHENYL)-PIPERIDINE
Synonyms: Albb-005757;4-(4-FLUORO-PHENYL)-PIPERIDINE;Piperidine, 4-(4-fluorophenyl)-;4-(Fluoro-phenyl)-piperidine hydrochloride
CBNumber: CB5306004
Molecular Formula: C11H14FN
Formula Weight: 179.23
MOL File: 37656-48-7.mol

More

Less

4-(4-FLUORO-PHENYL)-PIPERIDINE Property

Boiling point:: 258.6±40.0 °C(Predicted)
Density: 1.048±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 10.18±0.10(Predicted)
Appearance: Colorless to light yellow Liquid
InChI: InChI=1S/C11H14FN/c12-11-3-1-9(2-4-11)10-5-7-13-8-6-10/h1-4,10,13H,5-8H2
InChIKey: AFYALJSDFPSAAZ-UHFFFAOYSA-N
SMILES: N1CCC(C2=CC=C(F)C=C2)CC1
CAS DataBase Reference: 37656-48-7(CAS DataBase Reference)

More

Less

Safety

Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
HS Code: 2933599590

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: F1333
Product name: 4-(4-Fluorophenyl)piperidine
Purity: min. 98.0 %
Packaging: 250MG
Price: $120
Updated: 2025/07/31

TRC

Product number: B435120
Product name: 4-(4-Fluorophenyl)piperidine
Packaging: 100mg
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: W5851
Product name: 4-(4-Fluorophenyl)piperidine
Packaging: 250mg
Price: $89
Updated: 2021/12/16

Oakwood

Product number: 011727
Product name: 4-(4-Fluoro-phenyl)-piperidinehydrochloride
Packaging: 250mg
Price: $23
Updated: 2021/12/16

Oakwood

Product number: 011727
Product name: 4-(4-Fluoro-phenyl)-piperidinehydrochloride
Packaging: 1g
Price: $46
Updated: 2021/12/16

More

Less

4-(4-FLUORO-PHENYL)-PIPERIDINE Chemical Properties,Usage,Production

Synthesis

163630-89-5

37656-48-7

4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1-(phenylmethyl)pyridine (60 g, 225 mmol) was used as a raw material and dissolved in methanol (500 mL). To this solution, palladium/carbon hydroxide (20%, 5 g) was added and the reaction was shaken under hydrogen atmosphere (50 psi) for 48 hours. Upon completion of the reaction, the mixture was filtered through a glass fiber mat and washed with methanol. The filtrate was concentrated under reduced pressure to remove the solvent. The residue was dissolved in ethyl acetate and a 1 M solution of ether hydrogen chloride (300 mL) was added. The resulting solid was collected and recrystallized from 2-propanol to give 4-(4-fluorophenyl)piperidine hydrochloride as a colorless solid (30.5 g, 63% yield). Mass spectral data: m/z (ES+) 180 (M+1). The resulting 4-(4-fluorophenyl)piperidine hydrochloride sample (1 g, 4.64 mmol) was suspended in ethyl acetate and washed with saturated aqueous sodium carbonate. The organic layer was dried with anhydrous magnesium sulfate and the solvent was evaporated under reduced pressure to give the title compound 4-(4-fluorophenyl)piperidine as a colorless oil (825 mg, 99% yield). Mass spectral data: m/z (ES+) 180 (M+1).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2001, vol. 11, # 4, p. 495 - 500
[2] Patent: US6218390, 2001, B1
[3] European Journal of Medicinal Chemistry, 2005, vol. 40, # 12, p. 1197 - 1205
[4] Patent: US2003/236250, 2003, A1. Location in patent: Page 19

4-(4-FLUORO-PHENYL)-PIPERIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-(4-FLUORO-PHENYL)-PIPERIDINE Suppliers

China 73 Germany 1 India 2 Ukraine 1 United Kingdom 4 United States 20 Global 101

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 52923
Advantage: 58

Aceschem Inc.

Tel: +1-817863-6948 +1-（817）863-6948
Email: sales@aceschem.com
Country: United States
ProdList: 19632
Advantage: 58

Synthonix Inc

Tel: --
Fax: --
Email: info@synthonix.com
Country: United States
ProdList: 6872
Advantage: 58

CacheSyn Inc.

Tel: --
Fax: --
Email: info@cachesyn.com
Country: United States
ProdList: 695
Advantage: 50

HDH Pharma, Inc.

Tel: --
Fax: --
Email: catalog@hdhpharma.com
Country: United States
ProdList: 6248
Advantage: 62

AlliChem, LLC

Tel: --
Fax: --
Email: sales@allichemllc.com
Country: United States
ProdList: 6516
Advantage: 60

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

American Custom Chemicals Corporation

Tel: --
Fax: --
Email: sales@acccorporation.com
Country: United States
ProdList: 6820
Advantage: 51

Gainbiotech, LLC

Tel: --
Fax: --
Email: sales@gainbiotech.com
Country: United States
ProdList: 616
Advantage: 0

Oakwood Products, Inc.

Tel: --
Fax: --
Email: sales@oakwoodchemical.com
Country: United States
ProdList: 6193
Advantage: 74

AstaTech, Inc

Tel: --
Fax: --
Email: sales@astatechinc.com
Country: United States
ProdList: 6371
Advantage: 58

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

APAC Pharmaceutical, LLC

Tel: --
Fax: --
Email: sales@apacpharma.com
Country: United States
ProdList: 6322
Advantage: 38

ChemPacific Corporation

Tel: --
Fax: --
Email: sales@chempacific.com
Country: United States
ProdList: 6891
Advantage: 51

Rintech, Inc.

Tel: --
Fax: --
Email: info@rintechinc.com
Country: United States
ProdList: 3416
Advantage: 60

Allweys LLC

Tel: --
Fax: --
Email: sales@allweysllc.com
Country: United States
ProdList: 690
Advantage: 30

ASDI Incorporated

Tel: --
Fax: --
Email: customerservice@asdi.net
Country: United States
ProdList: 6922
Advantage: 67

More

Less

View Lastest Price from 4-(4-FLUORO-PHENYL)-PIPERIDINE manufacturers

Henan Fengda Chemical Co., Ltd

Product: 4-(4-FLUORO-PHENYL)-PIPERIDINE 37656-48-7
Price: US $101.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-28

Career Henan Chemical Co

Product: 4-(4-FLUORO-PHENYL)-PIPERIDINE 37656-48-7
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-08

37656-48-7, 4-(4-FLUORO-PHENYL)-PIPERIDINERelated Search:

Paroxetine maleate N-Methylparoxetine 4-(4-Fluorophenyl)-3-hydroxymethyl-1-methyl-piperidine Paroxetine 3-(Benzo[1,3]dioxol-5-yloxymethyl)-4-(4-fluoro-phenyl)-piperidine 4-(4-FLUORO-PHENYL)-PIPERIDINE 4-(4-FLUORO-PHENYL)-PIPERIDINE HYDROCHLORIDE Paroxetine hydrochloride TRANS-4-(4-FLUOROPHENYL)-3-PIPERIDINEME& 4-(4-FLUORO-PHENYL)-PIPERIDIN-4-OL HYDROCHLORIDE (-)-2-BETA-CARBOMETHOXY-3-BETA-(4-FLUOROPHENYL)TROPANE 4-(4-FLUORO-PHENYL)-PIPERIDINE HCL SALT 4-Aminomethyl-4-(4-fluoro-phenyl)-piperidine-1-carboxylic acid tert-butyl ester 4-(3-FLUORO-PHENYL)-PIPERIDINE Flazalone 4-(4-FLUOROPHENYL)-3-METHYL-2,6-DIPHENYLPIPERIDIN-4-OL HYDROCHLORIDE 4-(4-FLUOROPHENYL)-2,6-DIPHENYL-3-PROPYLPIPERIDIN-4-OL (3S,4R,5R)-1-BENZYL-5-CHLORO-4-(4-FLUORO-PHENYL)-PIPERIDINE-3-CARBOXYLIC ACID TERT-BUTYL ESTER

4-(4-FLUORO-PHENYL)-PIPERIDINE

4-(Fluoro-phenyl)-piperidine hydrochloride

Albb-005757

Piperidine, 4-(4-fluorophenyl)-

37656-48-7

C11H14FNHCl

C11H15FNCl