ChemicalBook > CAS DataBase List > MAl-PEG6-t-butyl ester

MAl-PEG6-t-butyl ester

Product Name
MAl-PEG6-t-butyl ester
CAS No.
518044-37-6
Chemical Name
MAl-PEG6-t-butyl ester
Synonyms
Mal-PEG6-Boc;Mal-PEG6-OtBu;Mal-PEG6-COOtBu;MAL-PEG6-CH2CH2COOTBU;MAl-PEG6-t-butyl ester;tert-butyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oate;4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester;Mal-PEG6-CH2CH2COOtBu/4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester
CBNumber
CB53062547
Molecular Formula
C23H39NO10
Formula Weight
489.56
MOL File
518044-37-6.mol
More
Less

MAl-PEG6-t-butyl ester Property

Boiling point:
565.2±50.0 °C(Predicted)
Density 
1.149±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
solubility 
Soluble in DMSO, DCM, DMF
pka
-2.34±0.20(Predicted)
form 
Viscous Liquid
color 
Light yellow to yellow
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

BroadPharm
Product number
BP-21523
Product name
Mal-PEG6-t-butylester
Purity
98%
Packaging
250mg
Price
$360
Updated
2021/12/16
Apolloscientific
Product number
BIPG1518
Product name
MAl-PEG6-t-butyl ester
Packaging
250mg
Price
$701
Updated
2021/12/16
Acrotein
Product number
B-1565
Product name
Mal-PEG6-CH2CH2COOtBu
Purity
97%
Packaging
1g
Price
$495
Updated
2021/12/16
More
Less

MAl-PEG6-t-butyl ester Chemical Properties,Usage,Production

Description

Mal-PEG6-t-butyl ester is a PEG linker containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

MAl-PEG6-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

MAl-PEG6-t-butyl ester Suppliers

Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5873
Advantage
58
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
Advantage
58
Zhengzhou Huiju Chemical Co., Ltd.
Tel
0371-55900031 18137872243
Email
3927209986@qq.com
Country
China
ProdList
10000
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28772
Advantage
58
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 13482353728
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
9964
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
Alpha Biopharmaceuticals Co., Ltd
Tel
0411-39042497
Fax
0411-39042693
Email
sales@alphabiopharm.com
Country
China
ProdList
1951
Advantage
58
Jiangsu aikang biomedical research and development co., LTD
Tel
025-58859352 17714375163
Email
qzhang@aikonchem.com
Country
China
ProdList
15525
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
Advantage
58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19908
Advantage
58
More
Less

View Lastest Price from MAl-PEG6-t-butyl ester manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
MAL-PEG6-COOtBu 518044-37-6
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2026-02-06
Xian confluore Biological Technology Co., Ltd.
Product
Mal-PEG6-COOtBu 518044-37-6
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-27

518044-37-6, MAl-PEG6-t-butyl esterRelated Search:


  • MAl-PEG6-t-butyl ester
  • MAL-PEG6-CH2CH2COOTBU
  • Mal-PEG6-OtBu
  • Mal-PEG6-COOtBu
  • Mal-PEG6-Boc
  • 4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester
  • Mal-PEG6-CH2CH2COOtBu/4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester
  • tert-butyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oate
  • 518044-37-6
  • C23H39NO10
  • peg